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006			m o d |
007			cr cnu||||||||
008			240724s1994 xx o ||||0 eng d
020			_a9780309572224 _q(electronic bk.)
035			_a(MiAaPQ)EBC3377315
035			_a(Au-PeEL)EBL3377315
035			_a(CaPaEBR)ebr10071339
035			_a(OCoLC)923269697
040			_aMiAaPQ _beng _erda _epn _cMiAaPQ _dMiAaPQ
050		4	_aTL1530 -- .N381 1994eb
082	0		_a629.477
100	1		_aConcentrations, Subcommittee on Spacecraft Maximum Allowable.
245	1	0	_aSpacecraft Maximum Allowable Concentrations for Selected Airborne Contaminants.
250			_a1st ed.
264		1	_aWashington : _bNational Academies Press, _c1994.
264		4	_c©1994.
300			_a1 online resource (235 pages)
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
505	0		_aSpacecraft Maximum Allowable Concentrations for Selected Airborne Contaminants -- Copyright -- Preface -- Contents -- Spacecraft Maximum Allowable Concentrations for Selected Airborne Contaminants -- INTRODUCTION -- SUMMARY OF REPORT ON GUIDELINES FOR DEVELOPING SMACS -- REVIEW OF SMAC REPORTS -- REFERENCES -- Appendix A Executive Summary of Guidelines for Developing Spacecraft Maximum Allowable Concentration for Space Station… -- EXECUTIVE SUMMARY: SPACECRAFT MAXIMUM ALLOWABLE CONCENTRATIONS FOR SPACE STATION CONTAMINANTS -- ENVIRONMENTAL CONTROL AND LIFE-SUPPORT SYSTEM -- MODIFICATION OF CONTAMINANT TOXICITY BY ENVIRONMENTAL FACTORS -- SOURCES AND TYPES OF DATA FOR ESTABLISHMENT OF SMACS -- Chemical-Physical Characteristics of Toxicants -- In Vitro Toxicity Studies -- Animal Toxicity Studies -- Clinical and Epidemiological Observations -- Pharmacokinetics and Metabolism -- Biological Markers -- RISK ASSESSMENT (DEVELOPMENT OF EXPOSURE CRITERIA) -- ISSUES IN MAKING RECOMMENDATIONS FOR THE ESTABLISHMENT OF SMACS -- Appendix B Reports on Spacecraft Maximum Allowable Concentrations (SMACs) for Selected Airborne Contaminants -- B1 ACETALDEHYDE -- PHYSICAL AND CHEMICAL PROPERTIES -- OCCURRENCE AND USE -- PHARMACOKINETICS AND METABOLISM -- TOXICITY SUMMARY -- Acute Toxicity -- Mucosal Irritation -- Miscellaneous Mucosal Effects -- Lethality -- Subchronic and Chronic Toxicity -- Nasal Toxicity -- Pulmonary and Renal Toxicity -- Carcinogenicity -- Genotoxicity -- Reproductive and Developmental Toxicity -- Synergistic Effects -- RATIONALE -- Carcinogenicity -- Mucosal Irritation -- The Establishment of SMACs -- REFERENCES -- B2 AMMONIA -- PHYSICAL AND CHEMICAL PROPERTIES -- OCCURRENCE AND USE -- PHARMACOKINETICS AND METABOLISM -- TOXICITY SUMMARY -- Mechanisms of Tissue Injuries -- Mucosal Irritation in Naive Subjects.
505	8		_aMucosal Irritation in Adapted Subjects -- Mucosal Irritation in Subjects Of Unknown Adaptation Status -- Toxic Effects of Massive Exposures -- Animal Models of Ammonia's Respiratory Damage -- Metabolic Acidosis -- RATIONALE -- 1-h SMAC and 24-h SMAC -- 7-d SMAC -- 30-d SMAC and 180-d SMAC -- REFERENCES -- B3 CARBON MONOXIDE -- PHYSICAL AND CHEMICAL PROPERTIES -- OCCURRENCE AND USE -- PHARMACOKINETICS -- TOXICITY SUMMARY -- Acute Toxicity -- Adaptation -- Subchronic and Chronic Toxicity -- Synergistic Effects -- RATIONALE -- 1-h SMAC -- 24-h SMAC -- 7-d SMAC -- 30-d SMAC and 180-d SMAC -- 1-h and 24-h SMACs Immediately Following CO Exposure -- REFERENCES -- B4 FORMALDEHYDE -- PHYSICAL AND CHEMICAL PROPERTIES -- OCCURRENCE AND USE -- PHARMACOKINETICS AND METABOLISM -- TOXICITY SUMMARY -- Acute Toxicity -- Subchronic and Chronic Toxicity -- Subchronic Data -- Chronic Data -- Epidemiological Data -- Genetic Toxicity -- Developmental Toxicity -- Synergistic Effects -- RATIONALE -- Mucosal Irritation -- Carcinogenesis -- Establishment of SMACs -- REFERENCES -- B5 FREON 113 -- PHYSICAL AND CHEMICAL PROPERTIES -- OCCURRENCE AND USE -- PHARMACOKINETICS -- TOXICITY SUMMARY -- Acute Toxicity (&lt -- 24 h Exposure) -- Lethality -- No-Observed-Adverse-Effect Level (NOAEL) -- Cardiac Arrhythmia -- CNS Effects -- Eye and Skin -- Sleepiness -- Subchronic Toxicity (1-13 w Exposure) -- NOAEL -- Biochemical Effects on the CNS -- Hepatotoxicity -- Chronic Toxicity (&gt -- 13 w Exposure) -- NOAEL -- Carcinogenicity and Genotoxicity -- Kidney Effects -- Memory and Psychomotor Effects -- Mechanistic Studies -- Spaceflight Effects -- Synergism -- RATIONALE -- REFERENCES -- B6 HYDROGEN -- PHYSICAL AND CHEMICAL PROPERTIES -- OCCURRENCE AND USE -- PHARMACOKINETICS AND METABOLISM -- TOXICITY SUMMARY -- EXPOSURE LIMITS -- RATIONALE -- REFERENCES -- B7 METHANE.
505	8		_aPHYSICAL AND CHEMICAL PROPERTIES -- OCCURRENCE AND USE -- PHARMACOKINETICS -- TOXICITY SUMMARY -- RATIONALE -- REFERENCES -- B8 METHANOL -- PHYSICAL AND CHEMICAL PROPERTIES -- OCCURENCE AND USE -- PHARMACOKINETICS AND METABOLISM -- TOXICITY SUMMARY -- Acute Toxicity -- Metabolic Acidosis, Headaches, and Ocular Toxicity -- CNS Effects Other Than Headaches -- Subchronic Toxicity -- Headaches and Ocular Toxicity -- Chronic and Genetic Toxicity -- Developmental Toxicity -- RATIONALE -- Headache -- 1-h AC -- 24-h AC -- 7-d, 30-d, and 180-d ACs -- Visual Disturbances -- 1-h AC -- 24-h AC -- 7-d, 30-d, and 180-d ACs -- Establishment of SMACs -- REFERENCES -- B9 OCTAMETHYLTRISILOXANE -- PHYSICAL AND CHEMICAL PROPERTIES -- OCCURRENCE AND USE -- PHARMACOKINETICS AND METABOLISM -- TOXICITY SUMMARY -- EXPOSURE LIMITS -- RATIONALE -- REFERENCES -- B10 TRIMETHYLSILANOL -- PHYSICAL AND CHEMICAL PROPERTIES -- OCCURRENCE AND USE -- PHARMACOKINETICS AND METABOLISM -- TOXICITY SUMMARY -- Acute and Short-Term Studies -- Subchronic and Chronic Studies -- Genotoxicity -- EXPOSURE LIMITS -- RATIONALE -- REFERENCES -- B11 VINYL CHLORIDE -- PHYSICAL AND CHEMICAL PROPERTIES -- OCCURRENCE AND USE -- PHARMACOKINETICS AND METABOLISM -- TOXICITY SUMMARY -- Acute and Short-Term Toxicity -- Mucosal Irritation -- Miscellaneous Symptoms -- Liver Toxicity -- Central Nervous System Toxicity -- Mortality -- Subchronic and Chronic Toxicity -- Liver Toxicity -- Kidney Toxicity -- Neurological Toxicity -- Effects on the Extremities -- Effects on the Respiratory System -- Effects on the Reproductive System -- Carcinogenicity -- Genotoxicity -- Developmental Toxicity -- Synergistic Effects -- RATIONALE -- Mucosal Irritation -- Headache -- CNS Impairment -- Non-neoplastic CNS Injury -- Liver Toxicity -- Kidney Toxicity -- Lung Toxicity -- Testicular Toxicity -- Carcinogenicity.
505	8		_aEstablishment of SMACs -- REFERENCES.
588			_aDescription based on publisher supplied metadata and other sources.
590			_aElectronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.
650		0	_aSpace cabin atmospheres.
650		0	_aSpace vehicles -- Air pollution.
650		0	_aSpace vehicles -- Air quality -- Standards.
650		0	_aSpace vehicles -- Contamination.
650		0	_aSpace vehicles -- Environmental aspects.
650		0	_aToxicology -- Research -- United States.
655		4	_aElectronic books.
700	1		_aToxicology, Committee on.
700	1		_aBoard on Environemental Studies and Toxicology, National Research Council.
776	0	8	_iPrint version: _aConcentrations, Subcommittee on Spacecraft Maximum Allowable _tSpacecraft Maximum Allowable Concentrations for Selected Airborne Contaminants _dWashington : National Academies Press,c1994
797	2		_aProQuest (Firm)
856	4	0	_uhttps://ebookcentral.proquest.com/lib/orpp/detail.action?docID=3377315 _zClick to View
999			_c84819 _d84819