000			03425nam a22004213i 4500
001			EBC3376453
003			MiAaPQ
005			20240729125245.0
006			m o d |
007			cr cnu||||||||
008			240724s1992 xx o ||||0 eng d
020			_a9780309572606 _q(electronic bk.)
020			_z9780309046886
035			_a(MiAaPQ)EBC3376453
035			_a(Au-PeEL)EBL3376453
035			_a(CaPaEBR)ebr10056726
035			_a(OCoLC)923263926
040			_aMiAaPQ _beng _erda _epn _cMiAaPQ _dMiAaPQ
050		4	_aRC268.4 -- .A35 1992eb
082	0		_a616.99
245	1	0	_aAdvances in Understanding Genetic Changes in Cancer : _bImpact on Diagnosis and Treatment Decisions in The 1990s.
250			_a1st ed.
264		1	_aWashington, D.C. : _bNational Academies Press, _c1992.
264		4	_c©1992.
300			_a1 online resource (96 pages)
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
505	0		_aADVANCES IN UNDERSTANDING GENETIC CHANGES IN CANCER -- Copyright -- Statement of Purpose -- Contents -- ADVANCES IN UNDERSTANDING GENETIC CHANGES IN CANCER -- 1 Introduction -- OUTLINE OF MOLECULAR GENETICS -- BRIEF OVERVIEW OF CANCER GENETICS -- 2 Testing for Tumor-Specific Genetic Markers -- MICROSCOPIC DETECTION OF ALTERATIONS IN DNA STRUCTURE -- In Situ Hybridization -- Ploidy Analysis -- TECHNIQUES FOR DETECTING CHANGES IN DNA STRUCTURE AT THE SUBMICROSCOPIC LEVEL -- Southern Blot Hybridization -- Pulsed-Field Gel Electrophoresis -- Polymerase Chain Reaction -- TECHNIQUES FOR DETECTION OF POINT MUTATIONS IN DNA -- TECHNIQUES DIRECTED AT ANALYSIS OF RNA -- TECHNIQUES FOR ANALYZING CHANGES AT THE PROTEIN LEVEL -- Immunohistochemistry -- 3 Hematologic Cancer -- CHRONIC MYELOGENOUS LEUKEMIA -- CHRONIC LYMPHOCYTIC LEUKEMIA -- ACUTE LYMPHOCYTIC LEUKEMIA -- ACUTE MYELOGENOUS LEUKEMIA -- MYELODYSPLASTIC SYNDROMES -- LYMPHOMA -- 4 Solid Tumors -- CHROMOSOMAL ABERRATIONS OF DIAGNOSTIC IMPORTANCE -- CHROMOSOMAL ABERRATIONS OF PROGNOSTIC IMPORTANCE -- Neuroblastoma -- Breast Cancer -- Lung Cancer -- Other Solid Tumors -- GENETIC MARKERS OF PREDISPOSITION TO CANCER -- Retinoblastoma -- Mapping of Other Cancer Predisposition Loci -- Li-Fraumeni Syndrome -- Loss of Heterozygosity in Sporadic Solid Tumors -- GENETIC CHANGES AND TUMOR PROGRESSION -- Colorectal Neoplasms -- Glial Tumors -- CANCER-ASSOCIATED GENETIC CHANGES AND ENVIRONMENTAL MUTAGENS -- VIRAL MARKERS IN CANCER DIAGNOSIS -- 5 Summary and Specific Recommendations -- PRACTICAL ASPECTS OF GENETIC ANALYSIS: FROM PATIENT TO DIAGNOSTIC LABORATORY -- THE MOLECULAR DIAGNOSTIC LABORATORY -- IMPLICATIONS OF COMMERCIALIZATION -- FUTURE NEEDS -- 6 References.
588			_aDescription based on publisher supplied metadata and other sources.
590			_aElectronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.
650		0	_aCancer -- Genetic aspects.
650		0	_aCancer -- Research -- United States.
655		4	_aElectronic books.
776	0	8	_iPrint version: _a _tAdvances in Understanding Genetic Changes in Cancer _dWashington, D.C. : National Academies Press,c1992 _z9780309046886
797	2		_aProQuest (Firm)
856	4	0	_uhttps://ebookcentral.proquest.com/lib/orpp/detail.action?docID=3376453 _zClick to View
999			_c84012 _d84012