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001			EBC3020567
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005			20240729124138.0
006			m o d |
007			cr cnu||||||||
008			240724s2008 xx o ||||0 eng d
020			_a9781616681258 _q(electronic bk.)
020			_z9781604563184
035			_a(MiAaPQ)EBC3020567
035			_a(Au-PeEL)EBL3020567
035			_a(CaPaEBR)ebr10677958
035			_a(OCoLC)556078922
040			_aMiAaPQ _beng _erda _epn _cMiAaPQ _dMiAaPQ
050		4	_aQP363 -- .W35 2008eb
082	0		_a612.8/2
100	1		_aWallace, Ron.
245	1	0	_aMembrane Microdomain Regulation of Neuron Signalling.
250			_a1st ed.
264		1	_aNew York : _bNova Science Publishers, Incorporated, _c2008.
264		4	_c©2008.
300			_a1 online resource (105 pages)
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
505	0		_aIntro -- MEMBRANE MICRODOMAINREGULATION OF NEURONSIGNALING -- NOTICE TO THE READER -- Contents -- Preface -- Introduction -- Membrane Studies:The Problem of Order -- 2.1. The Globule Model and the Membrane(1800-1850) -- 2.2. The German Reaction:The Membraneless State Model (1850-1890) -- 2.3. Early Models of the Cell Membrane(1895-1925) -- 2.4. The Davson-Danielli and FluidMosaic Models -- 2.5. The Fluid Mosaic Model Questioned:Chistyakov and Kinnunen -- 2.6. Ole Mouritsen and Myer Bloom:The Hydrophobic Mismatch (HM) Model -- 2.7. Hydrophobic Mismatch andNeural Evolution: Wallace and Price -- 2.8. Limitations of the HydrophobicMismatch (HM) Model -- 2.9. The Ordered Membrane:Fluorescence Studies -- Membrane MicrodomainRegulation of Neuron Signaling -- 3.1. The Resting Membrane is in aLiquid-Ordered State -- 3.2. Neural-Membrane MicrodomainsRespond to an Electric Field -- 3.3. Membrane Ethenes Are Polarized -- 3.3.1. First Computational Study: Rationale -- 3.3.2. First Computational Study: Method -- 3.3.3. First Computational Study: Results -- 3.3.4. Second Computational Study: Rationale -- 3.3.5. Second Computational Study: Method -- 3.3.5. Second Computational Study: Results -- 3.4. Membrane Dipoles InteractElectrostatically with Ion-Channel ChargeCenters -- 3.5. The Reset Mechanism: The Reversal ofField Effects -- Membrane Microdomains andNeural Impulse Propagation: FieldEffects in Cytoskeleton Corrals -- 4.1. Conduction Failure in Neurons:Evidence and Models -- 4.2. Regulated Lipid Diffusion throughCytoskeleton Gates -- 4.3. The KA Potassium Channel andNeural Impulse Regulation -- 4.4. Implications of the Model:Molecular Networks in the Neuron -- Toward Membrane MolecularMachines: Implications for theStudy ofNeural Disease -- 5.1. Artificial Model:Metallized Nanowire in a SupportedMembrane.
505	8		_a5.2. A Role for Artificial Membranes inModeling Neural Disease -- 5.3. Implications of the Proposed Model -- Conclusion -- Appendix: Table and Figures -- References -- Index.
588			_aDescription based on publisher supplied metadata and other sources.
590			_aElectronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.
650		0	_aNeurons.
650		0	_aCell membranes.
655		4	_aElectronic books.
776	0	8	_iPrint version: _aWallace, Ron _tMembrane Microdomain Regulation of Neuron Signalling _dNew York : Nova Science Publishers, Incorporated,c2008 _z9781604563184
797	2		_aProQuest (Firm)
856	4	0	_uhttps://ebookcentral.proquest.com/lib/orpp/detail.action?docID=3020567 _zClick to View
999			_c60906 _d60906