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| 001 | EBC3018914 | ||
| 003 | MiAaPQ | ||
| 005 | 20240729124108.0 | ||
| 006 | m o d | | ||
| 007 | cr cnu|||||||| | ||
| 008 | 240724s2009 xx o ||||0 eng d | ||
| 020 |
_a9781611220162 _q(electronic bk.) |
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| 020 | _z9781607410676 | ||
| 035 | _a(MiAaPQ)EBC3018914 | ||
| 035 | _a(Au-PeEL)EBL3018914 | ||
| 035 | _a(CaPaEBR)ebr10661853 | ||
| 035 | _a(OCoLC)923659647 | ||
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_aMiAaPQ _beng _erda _epn _cMiAaPQ _dMiAaPQ |
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| 050 | 4 | _aQR456 -- .V558 2009eb | |
| 082 | 0 | _a572.8/6292 | |
| 100 | 1 | _aFeng, Zhi. | |
| 245 | 1 | 0 |
_aViral Genomes : _bDiversity, Properties and Parameters. |
| 250 | _a1st ed. | ||
| 264 | 1 |
_aNew York : _bNova Science Publishers, Incorporated, _c2009. |
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| 264 | 4 | _c©2009. | |
| 300 | _a1 online resource (281 pages) | ||
| 336 |
_atext _btxt _2rdacontent |
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| 337 |
_acomputer _bc _2rdamedia |
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| 338 |
_aonline resource _bcr _2rdacarrier |
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| 505 | 0 | _aIntro -- VIRAL GENOMES: DIVERSITY,PROPERTIES AND PARAMETERS -- Contents -- Preface -- Correlations of Phylogenetic Relationwith Host Range, Length of ORF orGenes, Organization of ConservedSequences in the 3' Noncoding Region,and Viral Classification among theMembers of the Genus Flavivirus -- Abstract -- Introduction -- Viruses, Genomic Sequencing,and Phylogenetic Methods -- Viruses and Genomic Sequencing -- Phylogenetic Methods -- Recent Advancements in Phylogenetic Studies -- Correlation of Phylogeny withORF/Gene Length Range -- ORF and Gene Lengths -- Genome-Wide Linked Genetic Change -- Relationship between Length of ORF or Geneand Subgrouping of Members withinan RNA Virus Family -- Organization of Conserved Sequences in 3' NCR -- Host Range Specificity, Molecular Determinants,and Evolution of Multi-Phylum Pathogens -- Host Range Specificity -- Molecular Determinants -- Evolution of Multi-Phylum Pathogens -- Flaviviral Taxonomy -- Conclusion -- References -- Endogenous Retroviral SequencesControl the Transcription of ManyHost Genes in Eukaryotes -- Abbreviations -- Introduction -- Cis-Regulation of Gene Activity byLTR Retrotransposons in Mammals -- LTRs as Promoters for Transcriptionof the Host Genes -- LTRs as Transcriptional Enhancersfor the Cellular Genes -- LTRs as Transcriptional Silencers -- LTRs as Providers of New Splice Sitesfor the Host Genes -- LTRs as Sources of New Polyadenylation Signals -- LTRs as Antisense Regulators of theHost Gene Transcription -- Regulation of Gene Activity by the LTRRetrotransposons in Drosophila -- Conclusion -- Acknowledgments -- References -- A Secondary Structure Modelfor the 3'-Untranslated Regionof Ilarvirus RNAs -- Abstract -- Introduction -- Methods -- Results -- AMV-Type (Subgroups 3, 4 and 5) -- EMoV-Type (Subgroups 2 and 6) -- TSV-Type (Subgroup 1) -- Core Promoter Hairpin E. | |
| 505 | 8 | _aTRNA-Like Structures -- Conclusion -- Acknowledgments -- References -- Human T-Cell Leukemia VirusType 1 (HTLV-1) and AntiviralEnzyme APOBEC3 -- Abstract -- 1. Introduction -- 2. Human T cell Leukemia Virus Type 1 (Htlv-1) -- 2.1. Virology of HTLV-1 -- Genome Structure of HTLV-1 -- Tax Protein -- Do Defective Virus Genes Produce Viral Particles? -- 2.2. Virus Transmission -- 2.3. Infectious Molecular Clone -- Construction of Infectious Molecular Clone by PCR-Based Technology -- Full-Length Clone and 3′-LTR Deficient Clone -- Activation of Cryptic Splice Site in the Tax Gene by a Single NucleotideChange -- 3. Apobec3 -- 3.1. Antiviral Activity of APOBEC3 -- 3.2. APOBEC3 Targets a Variety of Retroviruses -- 3.3. Retrotransposon Restriction by APOBEC3 -- 3.4. Many APOBEC Protein-Subfamilies are Antiretroviral -- 4. HTLV-1 and APOBEC3 -- Conclusion -- References -- Is there a Critical Mass that wouldlikely trigger the Emergence of aPandemic Avian Influenza Genotype? -- Abstract -- Genetically Patterned Critical Masses -- Deductions from Past Pandemics andSignificant Outbreaks -- Critical Masses Underlying Virus Transmissibility -- Avian Hosts as Critical Mass Shapers -- Phylogeographically Related Critical Masses -- References -- Giant Viruses and their Genomes -- Abstract -- Introduction -- Blurred Boundary between Virus and Cell? -- Towards a Definition -- Giant Virus Characteristics -- Nucleocytoplasmic Large DNA Viruses (NCLDVs) -- Mimivirus -- Phycodnaviridae -- Other Giant Viruses -- Nimaviridae -- Poxviridae -- Herpesviridae -- Myoviridae -- Polydnaviruses -- Conclusion -- References -- Replication, Transcription, andTranslation of Coronaviruses -- Virology of Coronaviruses -- Viruses Belonging to the Family Coronaviridae -- 1. Feline Coronavirus (Fcov). | |
| 505 | 8 | _a2. Porcine Transmissible Gastroenteritis Virus(TGEV) and Porcine RespiratoryCoronavirus (Prcov) -- 3. Murine Hepatitis Virus (MHV) -- 4. Severe Acute Respiratory SyndromeCoronavirus (SARS-Cov) -- Conclusions -- References -- A Mathematical Model for theSuppressive Effect of SubgenomicHepatitis C Virus Replication inHuh-7 Cells in the Presenceof Potential Individual Drugs -- Abstract -- Introduction -- Materials and Methods -- Method Description -- Description of the Model -- Contribution of Inhibitors to the Model -- Estimation of Parameters -- Results -- Calculation of the Kinetics of HCV RNAConcentration in the Presence of the CompetitiveHCV NS3/NS4A Protease Inhibitors. -- Calculation of the Kinetics of HCV RNAConcentration in the Presence of theNoncompetitive Inhibitors ofHCV NS5B Polymerase -- Calculation of the Kinetics of HCV RNAConcentration in the Presence ofTranslation Initiation Inhibitors -- Discussion -- Acknowledgments -- References -- Comparative Sequence Analysis ofNorth American to South AmericanEastern Equine EncephalitisVirus Genomes -- Abstract -- Introduction -- Methods -- Results -- Conclusion -- Acknowledgments -- Disclaimer -- References -- Lyssavirus Genome -- Abstract -- 1. Introduction -- 2. Methods for Sequencing LyssavirusFull Genome -- 2. 1. Direct RT-PCR Method -- 2. 2. Rapid Amplification of Cdna Ends (RACE) -- 2.3. Circularization of Viral Genomic RNA -- 3. Lyssavirus Genome Organization -- 3.1. Non-Coding Regions -- 3.1.1.cis- and Trans-Acting Elements -- 3.1.1.1. Leader region (Le) -- 3.1.1.2. Trailer Region (Tr) -- 3.1.1.3. Gene Start, Transcription Termination-Polyadenylation (TTP),and Intergenic Sequences (IGS) -- 3.1.2. M-3' Non-Translated Region -- 3.1.3. G-L 3' Non-Translated Region (Ψ) -- 3.2. Coding Regions -- Nucleoprotein (N) -- Phosphoprotein (P) -- Matrix Protein (M) -- Glycoprotein (G). | |
| 505 | 8 | _aRNA Dependent RNA Polymerase (Rdrp Or L) -- 4. Genotypes in Lyssavirus -- 4.1. Update -- 4.2. Ancestor -- 5. Structural and Functional Constraints VersusEvolutionary Trends on Lyssavirus Genome -- 5.1. Structural and Functional Constraints by Potential ProteinCovariations -- 5.1.1. Covariations of the N Protein -- 5.1.2. Covariations Within and Among Viral Structural Proteins -- 5.1.3. Covariations of the R333 Residue in the G Protein -- 5.2. Evolutionary Driving Forces on Viral Structural Protein Genes -- Conclusions -- Acknowledgments -- References -- Disclaimer -- Index. | |
| 588 | _aDescription based on publisher supplied metadata and other sources. | ||
| 590 | _aElectronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries. | ||
| 650 | 0 | _aViral genetics. | |
| 650 | 0 | _aVirus diseases -- Genetic aspects. | |
| 655 | 4 | _aElectronic books. | |
| 700 | 1 | _aLong, Ming. | |
| 776 | 0 | 8 |
_iPrint version: _aFeng, Zhi _tViral Genomes _dNew York : Nova Science Publishers, Incorporated,c2009 _z9781607410676 |
| 797 | 2 | _aProQuest (Firm) | |
| 856 | 4 | 0 |
_uhttps://ebookcentral.proquest.com/lib/orpp/detail.action?docID=3018914 _zClick to View |
| 999 |
_c59940 _d59940 |
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