000			04733nam a22004933i 4500
001			EBC2031972
003			MiAaPQ
005			20240729123552.0
006			m o d |
007			cr cnu||||||||
008			240724s2010 xx o ||||0 eng d
020			_a9781469874821 _q(electronic bk.)
020			_z9781605474311
035			_a(MiAaPQ)EBC2031972
035			_a(Au-PeEL)EBL2031972
035			_a(CaPaEBR)ebr10824498
035			_a(OCoLC)686682029
040			_aMiAaPQ _beng _erda _epn _cMiAaPQ _dMiAaPQ
050		4	_aRC271.C5 -- C32219 2011eb
082	0		_a616.99/4061
100	1		_aChabner, Bruce A.
245	1	0	_aCancer Chemotherapy and Biotherapy : _bPrinciples and Practice.
250			_a5th ed.
264		1	_aPhiladelphia : _bWolters Kluwer Health, _c2010.
264		4	_c©2011.
300			_a1 online resource (836 pages)
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
505	0		_aCancer Chemotherapy and Biotherapy: Principles and Practice -- CONTENTS -- PREFACE -- ACKNOWLEDGMENTS -- CONTRIBUTORS -- Section I Basic Principles of Cancer Treatment -- Clinical Strategies for Cancer Treatment: The Role of Drugs -- Target Identifi cation and Drug Discovery -- Clinical Drug Development and Marketing Approval -- Principles of Pharmacokinetics -- Delivering Anticancer Drugs to Brain Tumors -- Pharmacogenetics -- Physical Barriers to Drug Delivery -- Section II Cytotoxic Agents -- Antifolates -- 5-Fluoropyrimidines -- Cytidine Analogues -- Purine Antimetabolites -- Hydroxyurea -- Antimitotic Drugs -- Alkylating Agents -- Platinum Analogues -- Bleomycin and Other Antitumor Antibiotics -- Topoisomerase I-Targeting Drugs -- Topoisomerase II Inhibitors: Anthracyclines -- Topoisomerase II Inhibitors: The Epipodophyllotoxins -- Asparaginase -- Section III Molecularly Targeted Therapies -- Proteasome Inhibitors -- Histone Deacetylase Inhibitors in Oncology -- Differentiating Agents -- Arsenic Trioxide -- Antibodies -- Inhibitors of Tumor Angiogenesis -- Epidermal Growth Factor Receptor Inhibitors -- HER2 Inhibitors -- Molecular Targeted Drugs -- Signaling Inhibitors: IGFR, PI3K Pathway, Embryonic Signaling Inhibitors, and Mitotic Kinase Inhibitors -- Section IV Immunologic Agents -- Cytokine Therapy for Cancer -- Cancer Vaccines -- Adoptive Cellular Therapies -- Thalidomide and Its Analogs in the Treatment of Hematologic Malignancies, Including Multiple Myeloma, and Solid Tumors -- Section V Hormonal Therapy -- Hormonal Therapy of Breast Cancer -- Hormone Therapy for Prostate Cancer -- Section VI Supportive Care -- Drug Therapy of Pain in Cancer Patients -- Hematopoietic Growth Factors -- Antinausea Medications -- Bisphosphonates and Other Bone-Targeted Therapies -- Intravenous Access and Catheter Management -- Section VII Survivorship.
505	8		_aLate Effects of Cancer Chemotherapy -- Infertility After Cancer Chemotherapy -- INDEX.
520			_aUpdated to include the newest drugs and those currently in development, this Fifth Edition is a comprehensive reference on the preclinical and clinical pharmacology of anticancer agents. Organized by drug class, the book provides the latest information on all drugs and biological agents-their mechanisms of action, interactions with other agents, toxicities, side effects, and mechanisms of resistance. The authors explain the rationale for use of drugs in specific schedules and combinations and offer guidelines for dose adjustment in particular situations. This edition's introduction includes timely information on general strategies for drug usage, the science of drug discovery and development, economic and regulatory aspects of cancer drug development, and principles of pharmacokinetics. Eight new chapters have been added and more than twenty have been significantly revised. A companion website includes the fully searchable text and an image bank.
588			_aDescription based on publisher supplied metadata and other sources.
590			_aElectronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.
650		0	_aCancer -- Chemotherapy.
650		0	_aCancer -- Immunotherapy.
650		0	_aAntineoplastic agents.
650		0	_aBiological response modifiers.
655		4	_aElectronic books.
700	1		_aLongo, Dan L.
776	0	8	_iPrint version: _aChabner, Bruce A. _tCancer Chemotherapy and Biotherapy _dPhiladelphia : Wolters Kluwer Health,c2010 _z9781605474311
797	2		_aProQuest (Firm)
856	4	0	_uhttps://ebookcentral.proquest.com/lib/orpp/detail.action?docID=2031972 _zClick to View
999			_c49913 _d49913