000 04733nam a22004933i 4500
001 EBC2031972
003 MiAaPQ
005 20240729123552.0
006 m o d |
007 cr cnu||||||||
008 240724s2010 xx o ||||0 eng d
020 _a9781469874821
_q(electronic bk.)
020 _z9781605474311
035 _a(MiAaPQ)EBC2031972
035 _a(Au-PeEL)EBL2031972
035 _a(CaPaEBR)ebr10824498
035 _a(OCoLC)686682029
040 _aMiAaPQ
_beng
_erda
_epn
_cMiAaPQ
_dMiAaPQ
050 4 _aRC271.C5 -- C32219 2011eb
082 0 _a616.99/4061
100 1 _aChabner, Bruce A.
245 1 0 _aCancer Chemotherapy and Biotherapy :
_bPrinciples and Practice.
250 _a5th ed.
264 1 _aPhiladelphia :
_bWolters Kluwer Health,
_c2010.
264 4 _c©2011.
300 _a1 online resource (836 pages)
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
505 0 _aCancer Chemotherapy and Biotherapy: Principles and Practice -- CONTENTS -- PREFACE -- ACKNOWLEDGMENTS -- CONTRIBUTORS -- Section I Basic Principles of Cancer Treatment -- Clinical Strategies for Cancer Treatment: The Role of Drugs -- Target Identifi cation and Drug Discovery -- Clinical Drug Development and Marketing Approval -- Principles of Pharmacokinetics -- Delivering Anticancer Drugs to Brain Tumors -- Pharmacogenetics -- Physical Barriers to Drug Delivery -- Section II Cytotoxic Agents -- Antifolates -- 5-Fluoropyrimidines -- Cytidine Analogues -- Purine Antimetabolites -- Hydroxyurea -- Antimitotic Drugs -- Alkylating Agents -- Platinum Analogues -- Bleomycin and Other Antitumor Antibiotics -- Topoisomerase I-Targeting Drugs -- Topoisomerase II Inhibitors: Anthracyclines -- Topoisomerase II Inhibitors: The Epipodophyllotoxins -- Asparaginase -- Section III Molecularly Targeted Therapies -- Proteasome Inhibitors -- Histone Deacetylase Inhibitors in Oncology -- Differentiating Agents -- Arsenic Trioxide -- Antibodies -- Inhibitors of Tumor Angiogenesis -- Epidermal Growth Factor Receptor Inhibitors -- HER2 Inhibitors -- Molecular Targeted Drugs -- Signaling Inhibitors: IGFR, PI3K Pathway, Embryonic Signaling Inhibitors, and Mitotic Kinase Inhibitors -- Section IV Immunologic Agents -- Cytokine Therapy for Cancer -- Cancer Vaccines -- Adoptive Cellular Therapies -- Thalidomide and Its Analogs in the Treatment of Hematologic Malignancies, Including Multiple Myeloma, and Solid Tumors -- Section V Hormonal Therapy -- Hormonal Therapy of Breast Cancer -- Hormone Therapy for Prostate Cancer -- Section VI Supportive Care -- Drug Therapy of Pain in Cancer Patients -- Hematopoietic Growth Factors -- Antinausea Medications -- Bisphosphonates and Other Bone-Targeted Therapies -- Intravenous Access and Catheter Management -- Section VII Survivorship.
505 8 _aLate Effects of Cancer Chemotherapy -- Infertility After Cancer Chemotherapy -- INDEX.
520 _aUpdated to include the newest drugs and those currently in development, this Fifth Edition is a comprehensive reference on the preclinical and clinical pharmacology of anticancer agents. Organized by drug class, the book provides the latest information on all drugs and biological agents-their mechanisms of action, interactions with other agents, toxicities, side effects, and mechanisms of resistance. The authors explain the rationale for use of drugs in specific schedules and combinations and offer guidelines for dose adjustment in particular situations. This edition's introduction includes timely information on general strategies for drug usage, the science of drug discovery and development, economic and regulatory aspects of cancer drug development, and principles of pharmacokinetics. Eight new chapters have been added and more than twenty have been significantly revised. A companion website includes the fully searchable text and an image bank.
588 _aDescription based on publisher supplied metadata and other sources.
590 _aElectronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.
650 0 _aCancer -- Chemotherapy.
650 0 _aCancer -- Immunotherapy.
650 0 _aAntineoplastic agents.
650 0 _aBiological response modifiers.
655 4 _aElectronic books.
700 1 _aLongo, Dan L.
776 0 8 _iPrint version:
_aChabner, Bruce A.
_tCancer Chemotherapy and Biotherapy
_dPhiladelphia : Wolters Kluwer Health,c2010
_z9781605474311
797 2 _aProQuest (Firm)
856 4 0 _uhttps://ebookcentral.proquest.com/lib/orpp/detail.action?docID=2031972
_zClick to View
999 _c49913
_d49913