000			04135nam a22004813i 4500
001			EBC5897807
003			MiAaPQ
005			20240724113940.0
006			m o d |
007			cr cnu||||||||
008			240724s2013 xx o ||||0 eng d
020			_a9781908230768 _q(electronic bk.)
020			_z9781908230072
035			_a(MiAaPQ)EBC5897807
035			_a(Au-PeEL)EBL5897807
035			_a(OCoLC)861536324
040			_aMiAaPQ _beng _erda _epn _cMiAaPQ _dMiAaPQ
050		4	_aQH447 .M35 2013
082	0		_a572.86
100	1		_aCarlton, Jane M.
245	1	0	_aMalaria Parasites : _bComparative Genomics, Evolution and Molecular Biology.
250			_a1st ed.
264		1	_aNorfolk : _bCaister Academic Press, _c2013.
264		4	_c©2013.
300			_a1 online resource (291 pages)
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
505	0		_aIntro -- Contents -- Preface -- Ch 01: The Diversity of Plasmodium and other Haemosporidians: The Intersection of Taxonomy, Phylogenetics and Genomics -- Ch 02: The Apicomplexan Genomic Landscape: The Evolutionary Context of Plasmodium -- Ch 03: Plasmodium Genomics and the Art of Sequencing Malaria Parasite Genomes -- Ch 04: Genome Diversity and Applications in Genetic Studies of the Human Malaria Parasites Plasmodium falciparum and Plasmodium vivax -- Ch 05: Functional Genomics of Plasmodium Parasites -- Ch 06: Plasmodium Experimental Genetic Crosses -- Ch 07: Regulation of Gene Expression -- Ch 08: Invasion of Host Red Blood Cells by Malaria Parasites -- Ch 09: Host Cell Remodelling and Protein Trafficking -- Ch 10: Dissecting Mosquito-Parasite Interactions through Molecular Biology and Biochemistry: Genomic, Proteomic and Glycomic Analyses -- Ch 11: The Malariologist's Molecular Toolbox.
520			_aSince the publication of the first two Plasmodium genome sequences in 2002, numerous other parasite genomes have been sequenced. These include the genomes of several more Plasmodium species as well as those of other apicomplexans, including species of Toxoplasma, Cryptosporidium, Babesia, and Eimeria. This wealth of genome sequence data has provided researchers with a powerful new tool, comparative genomics, which has revolutionised research in this area. In this book, expert authors from around the world comprehensively review the current advances in Plasmodium comparative genomics, highlighting the fascinating new insights into parasite evolution and molecular biology that have ensued. Topics include: Plasmodium taxonomy and phylogeny; the apicomplexan genomic landscape; the 'art' of sequencing Plasmodium genomes; diversity of Plasmodium falciparum and Plasmodium vivax genomes; Plasmodium functional genomics; Plasmodium experimental genetic crosses; P. falciparum epigenetic modification and transcriptional regulation; Plasmodium invasion of host red blood cells; protein export and trafficking by malaria parasites; Plasmodium-mosquito vector interactions; and a practical guide to many of the revolutionary new techniques and molecular tools for Plasmodium research. The book is essential reading for every researcher working with malaria parasites and related organisms, from the PhD student to the experienced scientist, and is a recommended text for all parasitologists.
588			_aDescription based on publisher supplied metadata and other sources.
590			_aElectronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.
650		0	_aComparative genomics.
650		0	_aMalaria.
650		0	_aMolecular parasitology.
650		0	_aParasites-Life cycles.
655		4	_aElectronic books.
700	1		_aPerkins, Susan L.
700	1		_aDeitsch, Kirk W.
776	0	8	_iPrint version: _aCarlton, Jane M. _tMalaria Parasites _dNorfolk : Caister Academic Press,c2013 _z9781908230072
797	2		_aProQuest (Firm)
856	4	0	_uhttps://ebookcentral.proquest.com/lib/orpp/detail.action?docID=5897807 _zClick to View
999			_c13417 _d13417