000			11076nam a22004813i 4500
001			EBC4933632
003			MiAaPQ
005			20240729131347.0
006			m o d |
007			cr cnu||||||||
008			240724s2017 xx o ||||0 eng d
020			_a9783662542569 _q(electronic bk.)
020			_z9783662542545
035			_a(MiAaPQ)EBC4933632
035			_a(Au-PeEL)EBL4933632
035			_a(CaPaEBR)ebr11420566
035			_a(OCoLC)999664949
040			_aMiAaPQ _beng _erda _epn _cMiAaPQ _dMiAaPQ
050		4	_aRD137-139
100	1		_aLedbetter, Daniel J.
245	1	0	_aEndocrine Surgery in Children.
250			_a1st ed.
264		1	_aBerlin, Heidelberg : _bSpringer Berlin / Heidelberg, _c2017.
264		4	_c©2018.
300			_a1 online resource (452 pages)
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
505	0		_aIntro -- Foreword -- Preface -- Acknowledgements -- Contents -- Contributors -- Thyroid -- 1 Thyroid Gland Embryology, Anatomy, and Physiology -- Thyroid Gland-Embryology, Anatomy, and Physiology -- Embryology of the Thyroid Gland -- Embryological Anomalies of the Thyroid with Clinical Significance -- Embryology of the Recurrent Laryngeal Nerve -- Anatomy of the Thyroid Gland -- Gross Anatomy -- Histology of the Thyroid Gland -- Thyroid Physiology -- Thyroid Hormone Synthesis -- Circulating Thyroid Hormones -- Cellular Effects of Thyroid Hormones -- Control of Thyroid Function by TSH -- Calcitonin -- References -- 2 Hyperthyroidism -- Pathophysiology -- Aetiology and Incidence -- Evaluation -- History -- Physical Examination -- Laboratory Tests -- Other Investigations -- Management -- Medical Management -- Radioactive Iodine Treatment -- Surgical Management of Hyperthyroidism -- Indications for Operative Management of Hyperthyroidism -- Preoperative Preparation -- Perioperative Anaesthesia Considerations -- Choice of Operation for Hyperthyroidism -- Postoperative Care -- Results of Thyroidectomy for Hyperthyroidism -- References -- 3 Thyroid Nodules in Children -- Incidence and Epidemiology -- Etiology -- Evaluation of Thyroid Nodules -- History and Physical Examination of the Child with a Thyroid Nodule -- Laboratory Tests to Evaluate Thyroid Nodules -- Imaging in the Evaluation of Thyroid Nodules -- Fine Needle Aspiration of Thyroid Nodules -- References -- 4 Thyroid Cancer in Children -- Incidence -- Epidemiology -- Etiology -- Risk of Thyroid Cancer After Radiation Exposure -- Risk of Thyroid Cancer in Syndromes -- Pathology -- Papillary Thyroid Cancer -- Follicular Thyroid Cancer -- Other Thyroid Cancers -- Clinical Presentations of Thyroid Cancer -- Evaluation -- Treatment -- Surgical Treatment -- Postoperative Staging.
505	8		_aPostoperative Radioactive Iodine Treatment -- Outcomes/Complications -- References -- Parathyroid -- 5 Parathyroid Gland Embryology, Anatomy and Physiology -- Parathyroid Embryology -- Parathyroid Anatomy -- Macroscopic Appearance of Parathyroid Glands -- Relationship of Parathyroid Glands to the Recurrent Laryngeal Nerves -- Blood Supply of Parathyroid Glands -- Ectopic Parathyroid Glands -- Histology -- Parathyroid Physiology -- Parathyroid Hormone -- References -- 6 Parathyroid Surgery in Children -- Incidence/Epidemiology -- Etiology -- Pathology -- Clinical Presentation -- History and Symptoms -- Physical Examination -- Blood Tests -- Imaging -- Indications for Operation -- Management -- Preoperative Management -- Hypercalcemic Crisis -- Operative Management -- Postoperative Management -- Complications -- Long-Term Outcomes and Follow-up -- References -- Adrenal -- 7 Adrenal Gland Embryology, Anatomy, and Physiology -- Embryology -- Adrenal Cortex Histology and Physiology -- Adrenal Medulla Histology and Physiology -- Adrenal Anatomy -- Relationship to Retroperitoneal Structures -- Venous Anatomy -- Arterial Anatomy -- Lymphatic Anatomy -- Anatomic Basis of Surgical Approaches to the Adrenal -- References -- 8 Pheochromocytoma -- Epidemiology -- Aetiology and Molecular Genetics -- Von Hippel-Lindau Disease (VHL) -- Multiple Endocrine Neoplasia Type 2A and 2B (MEN 2A and 2B) -- Neurofibromatosis Type 1 (Von Recklinghausen Disease) -- Hereditary Paraganglioma and Pheochromocytoma Syndromes -- Other Genetic Disorders -- Pathology -- Clinical Presentation -- Evaluation -- History -- Physical Examination -- Investigations -- Differential Diagnosis -- Imaging and Localisation -- Computerised Tomography (CT) and Magnetic Resonance Imaging (MRI) -- Other Imaging and Investigations -- Management -- Preoperative Management -- Surgery.
505	8		_aAdrenalectomy for PHEO -- Surgery for Thoracic and Abdominal PGL -- Surgery for Malignant PHEO -- Preoperative Considerations -- Intraoperative Considerations -- Operative Technique -- Right Adrenalectomy -- Left Adrenalectomy -- Bilateral Laparoscopic Adrenalectomy -- Open Adrenalectomy -- Post-operative Care -- Complications -- Intraoperative Complications -- Early Post-operative Complications -- Late Complications -- Follow-Up and Prognosis -- Other Treatment for Malignant Disease -- Radioactive 131I-MIBG -- Radioactive Somatostatin Analogues -- Chemotherapy, Radiotherapy and Novel Treatments -- References -- 9 Neuroblastoma -- History -- Clinical Features -- Investigation -- Treatment History -- Staging -- Pathology -- Molecular Pathology -- Risk-Based Therapy -- Predicting the Risk of Operation -- Predicting the Risk of Disease -- Treatment Strategies -- Localised Disease-No Image Defined Risk Factors (INSS Stage 1 and 2-INRG Stage L1) -- Localised Disease with Risk Factors (INSS Stage 3 INRG Stage L2) -- Metastatic Disease in Patient Over 18 Months of Age (INSS Stage 4 INRG Stage M) -- Metastatic 'Special' in a Patient Under 18 Months of Age (INSS Stage 4S, INRG Stage MS) -- Radiation Therapy -- Screening -- References -- 10 The Evaluation and Management of Adrenal Masses and Adrenocortical Tumors (Act) -- Physiology of Adrenocortical Tumors -- Etiology of Adrenocortical Tumors -- Epidemiology of Adrenocortical Tumors in Children -- Pathology of Adrenocortical Tumors in Children -- Gross Features of Adrenocortical Tumors in Children -- Microscopic Features of Adrenocortical Tumors in Children -- Adrenocortical Adenoma or Carcinoma? -- Evaluation of Adrenal Masses -- Symptoms and Signs of Adrenal Masses -- Laboratory Investigation of Adrenal Masses -- Imaging Evaluation of Adrenal Masses -- Differential Diagnosis of Adrenal Masses.
505	8		_aNeuroblastoma -- Pheochromocytoma -- Adrenal Hemorrhage -- Renal Lesions -- ACTH-Independent Macronodular Adrenal Hyperplasia (AIMAH) -- Primary Pigmented Nodular Adrenocortical Disease (PPNAD) -- Surgery for Adrenocortical Tumors -- Retroperitoneal Lymph Node Dissection (RPLND) -- Minimally Invasive Surgery for Adrenocortical Tumors in Children -- Staging of Adrenocortical Tumors -- Adjuvant Therapy -- Mitotane -- Chemotherapy -- Radiotherapy -- Future Therapeutic Options -- Outcomes -- Future Considerations -- References -- Pancreas -- 11 Pancreas Embryology, Anatomy, and Physiology -- Basic Anatomy -- Physiology -- Imaging -- Plain Abdominal Radiographs -- Abdominal Ultrasonography (US) -- Abdominal Computed Tomography (CT) Scans -- Endoscopic Retrograde Cholangiopancreatography (ERCP) -- Magnetic Resonance Cholangiopancreatography (MRCP) -- Other Imaging Modalities for the Endocrine Pancreas -- Basic Pancreatic Embryology -- Dorsal and Ventral Pancreatic Bud Development -- Initiation of the Pancreas with Endodermal Patterning -- Pancreatic Mesenchyme -- Key Signaling Molecules -- TGF-β Signaling -- Notch Signaling -- Hedgehog Signaling -- Wnt's -- Endothelial Cells and Oxygen Tension -- Endothelial Cells -- Extracellular Matrix -- Glucagon -- Transcription Factors -- PTf1a -- Ngn3 -- Rfx6 -- Nkx2.2 -- MafA/B -- Sox9 -- References -- 12 Congenital Hyperinsulinism -- Clinical Presentation and Diagnosis -- Pathophysiology of CHI -- Medical Management -- Histological Subtypes of Phhi -- Differential of Focal and Diffuse -- Surgery for CHI -- Surgery for Diffuse CHI -- Open Near-Total Pancreatectomy -- Laparoscopic Near-Total Pancreatectomy -- Surgery for Focal CHI -- Focal Lesion in Head or Neck of Pancreas -- Focal Lesion in Body or Tail of Pancreas -- Summary -- References -- 13 Pancreatic Neuroendocrine Tumours -- Aetiology.
505	8		_aPathology and Classification -- Clinical Presentation -- Functioning PaNETs -- Gastrinomas -- Insulinomas -- Other Functioning PNETs -- Non-functioning PaNETs -- Diagnosis -- Biochemical Tests -- Imaging -- Management -- Management of Functioning PaNETs -- Surgical Management -- Non-operative Management -- Management of Non-functioning PaNETs -- Outcomes and Prognosis -- Acknowledgements -- References -- 14 Islet Cell Transplantation -- Islet Transplantation: A Historical Perspective -- Donor Selection and Donor Availability -- Human Islet Isolation -- Pancreas Digestion -- Density Gradient Purification -- Islet Culture -- The Islet Transplant Procedure -- Pre-transplant Preparation -- The Transplant Procedure -- Post-transplant Care -- Complications -- Procedure-Related Complications -- Immunosuppression-Related Complications -- Clinical Islet Transplantation Outcomes -- Indications and Patient Selection for Islet Transplantation -- Pediatric Islet Allotransplantation-A Real Possibility? -- Concluding Remarks -- References -- 15 Diabetes in the Pediatric Surgical Patient -- Diagnosis -- Pathophysiology and Classification -- Normal Glucose Homeostasis -- Type 1 Diabetes -- Type 2 Diabetes -- Other Forms of Diabetes -- Treatment of Type 1 Diabetes -- Insulin Preparations and Regimens -- Insulin Pumps -- Blood Glucose Monitoring -- Treatment of Type 2 Diabetes -- Lifestyle Modification -- Metformin -- Sulfonylureas and Meglitinides -- Thiazolidinediones -- Insulin in Type 2 Diabetes -- Complications of Diabetes -- Diabetic Ketoacidosis (DKA) -- Hyperosmolar Hyperglycemic Syndrome (HHS) -- Hypoglycemia -- Risk of Infection -- Microvascular and Macrovascular Complications -- Preoperative Evaluation -- General Principles of Perioperative Management -- Diabetes Management in the Fasting Patient -- Intravenous Insulin Infusions -- Preparation for Surgery.
505	8		_aPerioperative Glycemic Control: Pathophysiology and Goals of Treatment.
588			_aDescription based on publisher supplied metadata and other sources.
590			_aElectronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.
650		0	_aSurgery.
655		4	_aElectronic books.
700	1		_aJohnson, Paul R. V.
776	0	8	_iPrint version: _aLedbetter, Daniel J. _tEndocrine Surgery in Children _dBerlin, Heidelberg : Springer Berlin / Heidelberg,c2017 _z9783662542545
797	2		_aProQuest (Firm)
856	4	0	_uhttps://ebookcentral.proquest.com/lib/orpp/detail.action?docID=4933632 _zClick to View
999			_c128665 _d128665