| 000 | 09930nam a22005173i 4500 | ||
|---|---|---|---|
| 001 | EBC4837610 | ||
| 003 | MiAaPQ | ||
| 005 | 20240729131202.0 | ||
| 006 | m o d | | ||
| 007 | cr cnu|||||||| | ||
| 008 | 240724s2017 xx o ||||0 eng d | ||
| 020 |
_a9781681084213 _q(electronic bk.) |
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| 020 | _z9781681084220 | ||
| 035 | _a(MiAaPQ)EBC4837610 | ||
| 035 | _a(Au-PeEL)EBL4837610 | ||
| 035 | _a(CaPaEBR)ebr11371045 | ||
| 035 | _a(OCoLC)983737714 | ||
| 040 |
_aMiAaPQ _beng _erda _epn _cMiAaPQ _dMiAaPQ |
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| 050 | 4 | _aRC388.5.N493 2017 | |
| 082 | 0 | _a616.80999999999995 | |
| 100 | 1 | _aRadaelli, Alberto. | |
| 245 | 1 | 0 | _aNew Concepts in Stroke Diagnosis and Therapy, (Current Developments in Stroke, Volume 1). |
| 250 | _a1st ed. | ||
| 264 | 1 |
_aSharjah : _bBentham Science Publishers, _c2017. |
|
| 264 | 4 | _c©2017. | |
| 300 | _a1 online resource (351 pages) | ||
| 336 |
_atext _btxt _2rdacontent |
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| 337 |
_acomputer _bc _2rdamedia |
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| 338 |
_aonline resource _bcr _2rdacarrier |
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| 490 | 1 |
_aCurrent Developments in Stroke ; _vv.1 |
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| 505 | 0 | _aIntro -- CONTENTS -- Foreword -- Preface 1 -- PREFACE 2 -- Preface 2 -- List of Contributors -- Stroke and Hypertension -- INTRODUCTION -- STROKE EPIDEMIOLOGY -- PATHOPHISIOLOGY OF BRAIN VASCULAR DAMAGE INDUCED BY HIGH BLOOD PRESSURE -- RELATIONSHIP BETWEEN HIGH BLOOD PRESSURE AND RISK OF STROKE -- HYPERTENSION THERAPY AND CEREBROVASCULAR DAMAGE PREVENTION -- Primary Stroke Prevention -- A Special Situation: Primary Stroke Prevention in the Very Elderly -- Secondary Stroke Prevention -- Hypertension Therapy and Early Cerebral Damage -- EVIDENCE OF THE RELATIONSHIP BETWEEN TREATMENT OF OTHER ASSOCIATED RISK FACTORS AND STROKE PREVENTION -- Type 2 Diabetes Mellitus -- Dyslipidemia -- IS THERE A NEUROPROTECTIVE EFFECT OF RENIN-ANGIOTENSIN SYSTEM BLOCKADE? -- CONCLUSION -- TAKE HOME MESSAGES -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENTS -- REFERENCES -- Autonomic Nervous System Dysfunction and Risk of Stroke -- INTRODUCTION -- Stroke Subtypes -- Cerebral Blood Vessels Innervation -- Sympathetic Innervation -- Parasympathetic Innervation -- Cerebral Blood Flow Auto-regulation -- Sympathetic Regulation of CBF -- Parasympathetic Regulation of Cerebral Blood Flow -- Vagal Modulation of Neuro-inflammation -- Baroreflex Modulation of Cerebral Blood Flow -- Autonomic Nervous System and the Risk of Stroke -- Blood Pressure Level, Blood Pressure Variability and Risk of Stroke -- Summary -- Methodological Aspects and Future Perspectives -- CONCLUSION -- TAKE HOME MESSAGES -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENTS -- REFERENCE -- Stroke and the Immune System: Therapeutic Targeting of Toll-Like Receptors -- 1. INTRODUCTION -- 2. INNATE IMMUNE CELLS AND THEIR REGULATION IN THE CNS -- 3. TLRS: STRUCTURE, ROLE AND EXPRESSION IN CNS -- 4. GENERAL CHARACTERISTICS AND IMMUNOLOGICAL ASPECTS OF STROKE -- 5. ROLE OF TLRS IN ISCHEMIC EVENTS. | |
| 505 | 8 | _a6. TLR TARGETING AS A PROMISING THERAPY IN CEREBRAL ISCHEMIA -- CONCLUSION AND FUTURE DIRECTIONS -- TAKE HOME MESSAGE: -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENTS -- REFERENCES -- Intracerebral Bleeding and Oral Anticoagulant Therapies: Clinical Relevance and Management -- 1. VKA-ASSOCIATED CEREBRAL HEMORRHAGES -- 1.1. Warfarin: Mechanism of Action and Main Characteristics -- 1.2. Monitoring Warfarin, and Risk of Intracerebral Bleeding -- 1.3. Reversal of VKA Effect and Management of VKA-Associated ICH -- 1.3.1. Vitamin K -- 1.3.2. FFP (Fresh Frozen Plasma) -- 1.3.3. About PCC (Prothrombin Complex Concentrates) -- 2. NON VITAMIN K ANTICOAGULANTS ASSOCIATED CEREBRAL HEMORRHAGES -- 2.1. DOACs Pharmacology -- 2.1.1. Dabigatran -- 2.1.2. Rivaroxaban -- 2.1.3. Apixaban -- 2.1.4. Edoxaban -- 2.2. DOACs Indications, Main Efficacy and Safety Data -- 2.3. DOACs Monitoring -- 2.3.1. Monitoring of Dabigatran -- 2.3.2. Monitoring of Direct Xa Inhibitors -- 2.4. DOACs Reversal and Management of Life Threatening Bleeding -- 2.4.1. General Principles for Managing Bleeding Related to Anticoagulants -- 2.4.2. Traditional Reversal Agents -- 2.4.3. Novel Reversal Strategies -- CONCLUSION -- TAKE HOME MESSAGES: -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENTS -- REFERENCES -- Cerebral Collateral Circulation in Acute Ischemic Stroke: Translational Evidence for Outcome Prediction and Modulation Strategies -- INTRODUCTION -- Cerebral Collateral Circulation in Humans and Rodents -- Assessment of Cerebral Collateral Flow in Acute Stroke Patients -- Cerebral Collateral Flow as Stratification Factor in Pre-Clinical Neuroprotection Studies -- Acute Therapeutic Modulation of Cerebral Collateral Flow -- CONCLUSION -- TAKE HOME MESSAGE -- CONFLICT OF INTEREST -- DISCLOSURE -- ACKNOWLEDGEMENTS -- REFERENCES -- Life in the Penumbra with the BRODERICK PROBE® -- INTRODUCTION -- METHODS. | |
| 505 | 8 | _aIn vitro Calibration Procedures -- In vivo Surgical Procedures -- Image Scanning Procedures -- Interpretation and Analysis of Data via Electrochemical Methods -- Middle Cerebral Artery Occlusion According to the Method of Zea Longa et al., 1989 -- Preparation of the Monofilament Nylon Suture -- Dual Laser Doppler Flowmetry (DLDF) -- RESULTS AND DISCUSSION -- NMI Data, Quantitative Histopathologic, and DLDF Data -- SUMMARY AND CONCLUSION -- NOTES FOR TABLE 2 -- Appendix: Overview of Nanotechnology Platforms for Stroke Diagnosis and Treatment -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENTS -- REFERENCES -- On the Influence of Normalization Strategies for Perfusion MRI in Acute Stroke -- INTRODUCTION -- SUBJECTS AND METHODS -- RESULTS -- DISCUSSION AND CONCLUSION -- TAKE HOME MESSAGE -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENTS -- REFERENCES -- Genetic Causes of Ischemic Stroke -- INTRODUCTION -- MONOGENIC STROKE DISORDERS -- Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) (OMIM 125310-600276) -- Cerebral Autosomal Recessive Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CARASIL) (OMIM 192315) -- Retinal Vasculopathy with Cerebral Leukodystrophy (RVCL) (OMIM 192315) -- Fabry Disease (OMIM #301500) -- COL4A1/A2 related Arteriopathy (OMIM 605595-120130) -- Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis and Stroke-Like Episodes (MELAS) (OMIM 540000) -- Multifactorial Stroke -- Stroke Subtypes Associations -- Limits of GWAS and Next Generation Studies -- CONCLUSION -- TAKE HOME MESSAGE -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENTS -- REFERENCES -- Diagnostic Challenges: Cryptogenic Ischemic Stroke -- ATRIAL FIBRILLATION: PREVALENCE AND THROMBOEMBOLIC RISK -- MECHANISM OF THROMBOSIS AND THROMBO-EMBOLI IN NON-VALVULAR ATRIAL FIBRILLATION -- CRYPTOGENIC STROKE AND ATRIAL FIBRILLATION. | |
| 505 | 8 | _aCONCLUSION -- TAKE HOME MESSAGE -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENTS -- REFERENCES -- Emerging Concepts for Neuroprotection -- INTRODUTION -- Neuroprotection -- Double Sword Process -- Systemic Variables -- Examples of Potential Neuroprotective Approaches -- Preconditioning and Ischemic Tolerance -- Hypothermia -- Minocycline -- CONCLUSION -- TAKE HOME MESSAGE -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENTS -- REFERENCES -- Pharmacological and Endovascular Recanalization Therapy -- INTRODUCTION -- Systemic Thrombolysis -- Indications for Intravenous Reperfusion Therapy -- Endovascular Treatment of Stroke (Thrombolysis, Thrombectomy, Thrombus Aspiration) -- Indications for Endovascular Therapy -- Post Treatment Phase -- CONCLUSION -- TAKE HOME MESSAGE -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENTS -- REFERENCES -- Neuroregeneration after Stroke -- INTRODUCTION -- Reparative Processes after Stroke -- Inflammation -- Neurogenesis -- Angiogenesis -- Astrogliosis -- Neuronal Plasticity Processes -- Post-Stroke Adaptive Plasticity Processes -- Re-emergence of a Critical Period after Stroke -- Brakes of Plasticity after Stroke -- Alteration of Brain Excitability after Stroke -- Approaches to Modulate Neural Plasticity -- Rehabilitation -- Non-Invasive Transcranial Stimulation -- Pharmacological Modulation of Neural Plasticity -- Modulation of GABA Signalling to Promote Plasticity -- Modulation of Glutamate Homeostasis to Promote Plasticity -- Neural Stem Cell-based Therapies -- CONCLUSION -- TAKE HOME MESSAGE -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENTS -- REFERENCES -- Post-Stroke Rehabilitation -- POST-STROKE REHABILITATION: ACUTE PHASE MANAGEMENT -- Prognosis -- Recovery of Independence in ADL and Social Participation -- Gait -- Upper Limb -- Continuity of Care Management -- POST-STROKE REHABILITATION: SUB-ACUTE PHASE MANAGEMENT. | |
| 505 | 8 | _aMain Sub-acute Phase Issues -- Post-stroke Cognitive Impairment -- Depression -- Spasticity -- Pain -- POST-STROKE REHABILITATION: CHRONIC PHASE MANAGEMENT -- WHAT'S NEW IN STROKE REHABILITATION -- Constraint Induced Movement Therapy (CIMT) -- Body Weight-Supported Treadmill Training (BWSTT) -- Robotic Devices -- Virtual Reality (VR) -- Action Observation (AO) -- Non-Invasive Brain Stimulation (NIBS) -- CONCLUSION -- TAKE HOME MESSAGE -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENTS -- REFERENCES -- SUBJECT INDEX. | |
| 588 | _aDescription based on publisher supplied metadata and other sources. | ||
| 590 | _aElectronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries. | ||
| 650 | 0 | _aCerebrovascular disease--Diagnosis. | |
| 655 | 4 | _aElectronic books. | |
| 700 | 1 | _aMancia, Giuseppe. | |
| 700 | 1 | _aFerrarese, Carlo. | |
| 776 | 0 | 8 |
_iPrint version: _aRadaelli, Alberto _tNew Concepts in Stroke Diagnosis and Therapy, (Current Developments in Stroke, Volume 1) _dSharjah : Bentham Science Publishers,c2017 _z9781681084220 |
| 797 | 2 | _aProQuest (Firm) | |
| 830 | 0 | _aCurrent Developments in Stroke | |
| 856 | 4 | 0 |
_uhttps://ebookcentral.proquest.com/lib/orpp/detail.action?docID=4837610 _zClick to View |
| 999 |
_c125112 _d125112 |
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