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Induction and Analysis of Antigen-Specific T Cell Responses in Melonoma Patients and Animal Models.

By: Material type: TextTextPublisher: Amsterdam : Leiden University Press, 2007Copyright date: ©2008Edition: 1st edDescription: 1 online resource (149 pages)Content type:
  • text
Media type:
  • computer
Carrier type:
  • online resource
ISBN:
  • 9789048505913
Subject(s): Genre/Form: Additional physical formats: Print version:: Induction and Analysis of Antigen-Specific T Cell Responses in Melonoma Patients and Animal ModelsDDC classification:
  • 610
LOC classification:
  • RC280.M37 -- B56 2008eb
Online resources:
Contents:
Intro -- Contents -- Introduction -- 1: On the Role of Melanoma-Specific CD8+ T-Cell Immunity in Disease Progression of Advanced-Stage Melanoma Patients. -- 2: Phase I clinical study with multiple peptide vaccines in combination with tetanus toxoid and GM-CSF in advanced-stage HLA-A*0201- positive melanoma patients. -- 3: A rapid and potent DNA vaccination strategy defined by in vivo monitoring of antigen expression -- 4: Superior immunogenicity of DNA tattooing as compared to intramuscular DNA vaccination in non-human primates. -- 5: In vivo antigen stability affects vaccine efficacy -- 6: Intravital imaging of fluorescent markers and FRET probes by DNA tattooing. -- 7: Design and use of conditional MHC class I ligands -- Discussion -- Dutch Summary -- Acknowledgements and Curriculum Vitae.
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Intro -- Contents -- Introduction -- 1: On the Role of Melanoma-Specific CD8+ T-Cell Immunity in Disease Progression of Advanced-Stage Melanoma Patients. -- 2: Phase I clinical study with multiple peptide vaccines in combination with tetanus toxoid and GM-CSF in advanced-stage HLA-A*0201- positive melanoma patients. -- 3: A rapid and potent DNA vaccination strategy defined by in vivo monitoring of antigen expression -- 4: Superior immunogenicity of DNA tattooing as compared to intramuscular DNA vaccination in non-human primates. -- 5: In vivo antigen stability affects vaccine efficacy -- 6: Intravital imaging of fluorescent markers and FRET probes by DNA tattooing. -- 7: Design and use of conditional MHC class I ligands -- Discussion -- Dutch Summary -- Acknowledgements and Curriculum Vitae.

Description based on publisher supplied metadata and other sources.

Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.

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