Rabies : Symptoms, Treatment and Prevention.

Intro -- RABIES: SYMPTOMS, TREATMENT AND PREVENTION -- RABIES: SYMPTOMS, TREATMENT AND PREVENTION -- CONTENTS -- PREFACE -- Chapter 1 RABIES PREVENTION: CURRENT TRENDS IN ANTI-RABIES VACCINES -- ABSTRACT -- INTRODUCTION TO RABIES -- THE RABIES VIRUS, GENERAL STRUCTURE -- RABIES VIRUS GLYCOPROTEIN, RVGP, AND IMPLICATION IN DISEASE -- RABIES SYMPTOMS, DIAGNOSIS AND PREVENTION -- TRENDS IN RABIES VACCINES AND POST-EXPOSURE TREATMENT -- Initial Rabies Vaccines -- HDCC Vaccines -- PCEC Vaccines -- Vero-cell Derived Vaccines -- Towards Better Vaccines -- Current Rabies Situation -- NEW TECHNOLOGIES IN RABIES VACCINE THERAPIES -- DNA-BASED VACCINATION APPROACHES -- Plasmid DNA Vaccines -- Pseudorabies DNA Viral Vaccines -- Poxvirus DNA Vaccines -- Adenovirus DNA Vaccines -- Limitations of DNA Vaccines -- Alternative Vaccine Approaches -- DEVELOPMENT OF ALPHAVIRAL-BASED ANTI-RABIES VACCINATIONS -- Alphaviruses and Clinical Applications -- Alphaviruses in Vaccine Therapies -- Alphaviruses in Rabies Vaccination -- OVERVIEW AND CONCLUSION -- REFERENCES -- Chapter 2 RABIES: EPIDEMIOLOGY, PATHOGENESIS, AND PROPHYLAXIS+ -- ABSTRACT -- INTRODUCTION -- EPIDEMIOLOGY -- VIROLOGY -- PATHOGENESIS -- CLINICAL MANIFESTATIONS -- DIFFERENTIAL DIAGNOSIS -- LABORATORY DIAGNOSIS -- TREATMENT -- PREVENTION -- Control of Rabies -- Preexposure Prophylaxis -- Post-Exposure Prophylaxis -- CONCLUSION -- REFERENCES -- Chapter 3 RABIES VIRUS EVASION OF THE INTERFERON SYSTEM -- ABSTRACT -- INTRODUCTION -- THE TYPE I IFN SYSTEM: KEY PLAYER IN RABIES ANTIVIRAL IMMUNITY -- RECOGNITION OF RABIES VIRUS PAMPS AND IFN INDUCTION BY RECEPTORS OF THE INNATE IMMUNE SYSTEM -- RABIES VIRUS COUNTERMEASURES TO THE IFN SYSTEM -- Rabies Virus Phosphoprotein P Inhibits IFN Induction. -- Rabies Virus Phosphoprotein P Inhibits IFN Signaling and ISG Expression.

REVERSE GENETICS TO GENERATE IFN COMPROMISED RABIES VIRUSES -- CONCLUSION -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 4 ADVANCES IN RABIES LABORATORY DIAGNOSIS IN BRAZIL -- INTRODUCTION -- EPIDEMIOLOGICAL SITUATION OF RABIES -- RABIES DIAGNOSTIC IN BATS -- FLUORESCENT ANTIBODIES FOR RABIES -- MONOCLONAL ANTIBODIES FOR RABIES -- MOLECULAR BIOLOGY OF THE RABIES VIRUS -- IMMUNOHYSTOCHEMISTRY IN THE DIAGNOSTIC OF RABIES -- ANTE-MORTEM LABORATORY DIAGNOSTIC -- REFERENCES -- Chapter 5 ANTIBODY SEROPREVALENCE AGAINST RABIES OF FREE-ROAMING DOGS IN BOLIVIA -- ABSTRACT -- INTRODUCTION -- Rabies in Bolivia -- Rabies Control Measures in Santa Cruz de la Sierra -- Research on canine rabies in Santa Cruz de la Sierra -- MATERIALS AND METHODS -- Study Area -- Study Animals -- Serum Collection and Laboratory Analysis -- Data Analysis and Mathematical Model -- RESULTS -- DISCUSSION -- CONCLUSION -- ACKNOWLEDGMENTS -- REFERENCES -- REVIEWED BY -- Chapter 6 LYSSAVIRUS GENOME -- ABSTRACT -- 1. INTRODUCTION -- 2. METHODS FOR SEQUENCING LYSSAVIRUS FULL GENOME -- 2.1. Direct RT-PCR Method -- 2. 2. Rapid Amplification of Cdna Ends (RACE) -- 2.3. Circularization of Viral Genomic RNA -- 3. LYSSAVIRUS GENOME ORGANIZATION -- 3.1. Non-Coding Regions -- 3.1.1.cis- and Trans-Acting Elements -- 3.1.1.1. Leader region (Le) -- 3.1.1.2. Trailer Region (Tr) -- 3.1.1.3. Gene start, transcription termination-polyadenylation (TTP), and intergenic sequences (IGS) -- 3.1.2. M-3' non-translated region -- 3.1.3. G-L 3' non-translated region (Ψ) -- 3.2. CODING REGIONS -- Nucleoprotein (N) -- Phosphoprotein (P) -- Matrix Protein (M) -- Glycoprotein (G) -- RNA Dependent RNA Polymerase (Rdrp or L) -- 4. GENOTYPES IN LYSSAVIRUS -- 4.1. Update -- 4.2. Ancestor -- 5. STRUCTURAL AND FUNCTIONAL CONSTRAINTS VERSUS EVOLUTIONARY TRENDS ON LYSSAVIRUS GENOME.

5.1. Structural and Functional Constraints by Potential Protein Covariations -- 5.1.1. Covariations of the N Protein -- 5.1.2. Covariations Within and Among Viral Structural Proteins -- 5.1.3. Covariations of the R333 residue in the G protein -- 5.2. Evolutionary Driving Forces on Viral Structural Protein Genes -- CONCLUSION -- ACKNOWLEDGMENTS -- REFERENCES -- DISCLAIMER -- Chapter 7 RABIES AND FREE RADICAL: A RELATIONSHIP -- ABSTRACT -- INTRODUCTION -- FREE RADICAL IN ENCEPHALITIS: WHAT IS ITS ORIGIN? -- PUBLICATION ON RABIES AND FREE RADICAL -- BORNA DISEASE: ANOTHER ENCEPHALITIS VIRUS INFECTION RELATING TO FREE RADICAL -- REFERENCES -- INDEX.

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Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.