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Cardiovascular System : Cold Spring Harbor Symposia on Quantitative Biology.

By: Contributor(s): Material type: TextTextPublisher: Woodbury : Cold Spring Harbor Laboratory Press, 2001Copyright date: ©2002Edition: 1st edDescription: 1 online resource (588 pages)Content type:
  • text
Media type:
  • computer
Carrier type:
  • online resource
ISBN:
  • 9780879696788
Subject(s): Genre/Form: Additional physical formats: Print version:: Cardiovascular SystemLOC classification:
  • QM181 -- .C64 2002eb
Online resources:
Contents:
Intro -- Symposium Participants -- Foreword -- Contents -- Cardiogenesis in the Drosophila Model: Control Mechanisms during Early Induction and Diversification of Cardiac Progenitors -- Regulation of Cardiac Muscle Differentiation in Xenopus laevis Embryos -- Genetic Regulation of Cardiac Patterning in Zebrafish -- Zebrafish Hearts and Minds: Nodal Signaling in Cardiac and Neural Left- Right Asymmetry -- Cardiac Left-Right Development: Are the Early Steps Conserved? -- Erythropoietin and Retinoic Acid Signaling in the Epicardium Is Required for Cardiac Myocyte Proliferation -- Endocardial Cushion Formation in Zebrafish -- Neural Crest Migration and Mouse Models of Congenital Heart Disease -- Hey bHLH Factors in Cardiovascular Development -- Molecular Mechanisms of Chamber-specific Myocardial Gene Expression: Transgenic Analysis of the ANF Promoter -- Pitx Genes during Cardiovascular Development -- Pitx2 and Cardiac Development: A Molecular Link between Left/ Right Signaling and Congenital Heart Disease -- Regulation of Cardiac Growth and Development by SRF and Its Cofactors -- Homeodomain Factor Nkx2-5 in Heart Development and Disease -- Causes of Clinical Diversity in Human TBX5 Mutations -- Molecular Mechanisms of Ventricular Hypoplasia -- Hypoxia, HIFs, and Cardiovascular Development -- Quiescent Hypervascularity Mediated by Gain of HIF- 1a Function -- The Diverse Roles of Integrins and Their Ligands in Angiogenesis -- Arteries, Veins, Notch, and VEGF -- Cell Cycle Signaling and Cardiovascular Disease -- Selective Functions of Angiopoietins and Vascular Endothelial Growth Factor on Blood Vessels: The Concept of Ï Vascular DomainÓ -- Survival Mechanisms of VEGF and PlGF during Microvascular Remodeling -- Molecular Mechanisms of Lymphangiogenesis -- Protease-activated Receptors in the Cardiovascular System.
Migration of Monocytes/Macrophages In Vitro and In Vivo Is Accompanied by MMP12- dependent Tunnel Formation and by Neovascularization -- The Role of EG-VEGF in the Regulation of Angiogenesis in Endocrine Glands -- Profiling the Molecular Diversity of Blood Vessels -- VEGF-A Induces Angiogenesis, Arteriogenesis, Lymphangiogenesis, and Vascular Malformations -- Angiogenesis and Lymphangiogenesis in Tumors: Insights from Intravital Microscopy -- A Genetic Approach to Understanding Tumor Angiogenesis -- Discovery of Type IV Collagen Non-collagenous Domains as Novel Integrin Ligands and Endogenous Inhibitors of Angiogenesis -- Complementary and Coordinated Roles of the VEGFs and Angiopoietins during Normal and Pathologic Vascular Formation -- Involvement of G Proteins in Vascular Permeability Factor/ Vascular Endothelial Growth Factor Signaling -- Targeted Delivery of Mutant Raf Kinase to Neovessels Causes Tumor Regression -- Combining Antiangiogenic Agents with Metronomic Chemotherapy Enhances Efficacy against Late- stage Pancreatic Islet Carcinomas in Mice -- Zebrafish: The Complete Cardiovascular Compendium -- Consomic Rats for the Identification of Genes and Pathways Underlying Cardiovascular Disease -- A Mouse Model of Congenital Heart Disease: Cardiac Arrhythmias and Atrial Septal Defect Caused by Haploinsufficiency of the Cardiac Transcription Factor Csx/ Nkx2.5 -- Genetic Dissection of the DiGeorge Syndrome Phenotype -- A Missense Mutation in a Highly Conserved Region of CASQ2 Is Associated with Autosomal Recessive Catecholamine- induced Polymorphic Ventricular Tachycardia in Bedouin Families from Israel -- Calcium-dependent Gene Regulation in Myocyte Hypertrophy and Remodeling -- A Gradient of Myosin Regulatory Light-chain Phosphorylation across the Ventricular Wall Supports Cardiac Torsion.
Molecular and Functional Maturation of the Murine Cardiac Conduction System -- The Yin/Yang of Innate Stress Responses in the Heart -- Regulatory Networks Controlling Mitochondrial Energy Production in the Developing, Hypertrophied, and Diabetic Heart -- Molecular Epidemiology of Hypertrophic Cardiomyopathy -- The Sarcoglycan Complex in Striated and Vascular Smooth Muscle -- The MLP Family of Cytoskeletal Z Disc Proteins and Dilated Cardiomyopathy: A Stress Pathway Model for Heart Failure Progression -- From Sarcomeric Mutations to Heart Disease: Understanding Familial Hypertrophic Cardiomyopathy -- Vascular Endothelium in Tissue Remodeling: Implications for Heart Failure -- Using a Gene-switch Transgenic Approach to Dissect Distinct Roles of MAP Kinases in Heart Failure -- G-Protein-coupled Receptor Function in Heart Failure -- Salt and Blood Pressure: New Insight from Human Genetic Studies -- Gene-targeting Studies of the Renin-Angiotensin System: Mechanisms of Hypertension and Cardiovascular Disease -- Modulation of Endothelial NO Production by High- density Lipoprotein -- Plaque Angiogenesis: Its Functions and Regulation -- Extracellular Superoxide Dismutase, Uric Acid, and Atherosclerosis -- SREBPs: Transcriptional Mediators of Lipid Homeostasis -- Genetic Defenses against Hypercholesterolemia -- Insulin-like Growth Factor Isoforms in Skeletal Muscle Aging, Regeneration, and Disease -- Cellular Therapies for Myocardial Infarct Repair -- Gene Therapy for Cardiac Arrhythmias -- Myocardial Disease in Failing Hearts: Defective Excitation-Contraction Coupling -- The Coming of Age of Cardiovascular Science -- Author Index -- Subject Index.
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Intro -- Symposium Participants -- Foreword -- Contents -- Cardiogenesis in the Drosophila Model: Control Mechanisms during Early Induction and Diversification of Cardiac Progenitors -- Regulation of Cardiac Muscle Differentiation in Xenopus laevis Embryos -- Genetic Regulation of Cardiac Patterning in Zebrafish -- Zebrafish Hearts and Minds: Nodal Signaling in Cardiac and Neural Left- Right Asymmetry -- Cardiac Left-Right Development: Are the Early Steps Conserved? -- Erythropoietin and Retinoic Acid Signaling in the Epicardium Is Required for Cardiac Myocyte Proliferation -- Endocardial Cushion Formation in Zebrafish -- Neural Crest Migration and Mouse Models of Congenital Heart Disease -- Hey bHLH Factors in Cardiovascular Development -- Molecular Mechanisms of Chamber-specific Myocardial Gene Expression: Transgenic Analysis of the ANF Promoter -- Pitx Genes during Cardiovascular Development -- Pitx2 and Cardiac Development: A Molecular Link between Left/ Right Signaling and Congenital Heart Disease -- Regulation of Cardiac Growth and Development by SRF and Its Cofactors -- Homeodomain Factor Nkx2-5 in Heart Development and Disease -- Causes of Clinical Diversity in Human TBX5 Mutations -- Molecular Mechanisms of Ventricular Hypoplasia -- Hypoxia, HIFs, and Cardiovascular Development -- Quiescent Hypervascularity Mediated by Gain of HIF- 1a Function -- The Diverse Roles of Integrins and Their Ligands in Angiogenesis -- Arteries, Veins, Notch, and VEGF -- Cell Cycle Signaling and Cardiovascular Disease -- Selective Functions of Angiopoietins and Vascular Endothelial Growth Factor on Blood Vessels: The Concept of Ï Vascular DomainÓ -- Survival Mechanisms of VEGF and PlGF during Microvascular Remodeling -- Molecular Mechanisms of Lymphangiogenesis -- Protease-activated Receptors in the Cardiovascular System.

Migration of Monocytes/Macrophages In Vitro and In Vivo Is Accompanied by MMP12- dependent Tunnel Formation and by Neovascularization -- The Role of EG-VEGF in the Regulation of Angiogenesis in Endocrine Glands -- Profiling the Molecular Diversity of Blood Vessels -- VEGF-A Induces Angiogenesis, Arteriogenesis, Lymphangiogenesis, and Vascular Malformations -- Angiogenesis and Lymphangiogenesis in Tumors: Insights from Intravital Microscopy -- A Genetic Approach to Understanding Tumor Angiogenesis -- Discovery of Type IV Collagen Non-collagenous Domains as Novel Integrin Ligands and Endogenous Inhibitors of Angiogenesis -- Complementary and Coordinated Roles of the VEGFs and Angiopoietins during Normal and Pathologic Vascular Formation -- Involvement of G Proteins in Vascular Permeability Factor/ Vascular Endothelial Growth Factor Signaling -- Targeted Delivery of Mutant Raf Kinase to Neovessels Causes Tumor Regression -- Combining Antiangiogenic Agents with Metronomic Chemotherapy Enhances Efficacy against Late- stage Pancreatic Islet Carcinomas in Mice -- Zebrafish: The Complete Cardiovascular Compendium -- Consomic Rats for the Identification of Genes and Pathways Underlying Cardiovascular Disease -- A Mouse Model of Congenital Heart Disease: Cardiac Arrhythmias and Atrial Septal Defect Caused by Haploinsufficiency of the Cardiac Transcription Factor Csx/ Nkx2.5 -- Genetic Dissection of the DiGeorge Syndrome Phenotype -- A Missense Mutation in a Highly Conserved Region of CASQ2 Is Associated with Autosomal Recessive Catecholamine- induced Polymorphic Ventricular Tachycardia in Bedouin Families from Israel -- Calcium-dependent Gene Regulation in Myocyte Hypertrophy and Remodeling -- A Gradient of Myosin Regulatory Light-chain Phosphorylation across the Ventricular Wall Supports Cardiac Torsion.

Molecular and Functional Maturation of the Murine Cardiac Conduction System -- The Yin/Yang of Innate Stress Responses in the Heart -- Regulatory Networks Controlling Mitochondrial Energy Production in the Developing, Hypertrophied, and Diabetic Heart -- Molecular Epidemiology of Hypertrophic Cardiomyopathy -- The Sarcoglycan Complex in Striated and Vascular Smooth Muscle -- The MLP Family of Cytoskeletal Z Disc Proteins and Dilated Cardiomyopathy: A Stress Pathway Model for Heart Failure Progression -- From Sarcomeric Mutations to Heart Disease: Understanding Familial Hypertrophic Cardiomyopathy -- Vascular Endothelium in Tissue Remodeling: Implications for Heart Failure -- Using a Gene-switch Transgenic Approach to Dissect Distinct Roles of MAP Kinases in Heart Failure -- G-Protein-coupled Receptor Function in Heart Failure -- Salt and Blood Pressure: New Insight from Human Genetic Studies -- Gene-targeting Studies of the Renin-Angiotensin System: Mechanisms of Hypertension and Cardiovascular Disease -- Modulation of Endothelial NO Production by High- density Lipoprotein -- Plaque Angiogenesis: Its Functions and Regulation -- Extracellular Superoxide Dismutase, Uric Acid, and Atherosclerosis -- SREBPs: Transcriptional Mediators of Lipid Homeostasis -- Genetic Defenses against Hypercholesterolemia -- Insulin-like Growth Factor Isoforms in Skeletal Muscle Aging, Regeneration, and Disease -- Cellular Therapies for Myocardial Infarct Repair -- Gene Therapy for Cardiac Arrhythmias -- Myocardial Disease in Failing Hearts: Defective Excitation-Contraction Coupling -- The Coming of Age of Cardiovascular Science -- Author Index -- Subject Index.

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Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.

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