Muscular and Skeletal Anomalies in Human Trisomy in an Evo-Devo Context : Description of a T18 Cyclopic Fetus and Comparison Between Edwards (T18), Patau (T13) and down (T21) Syndromes Using 3-D Imaging and Anatomical Illustrations.

Front Cover -- Preface -- Acknowledgements -- Contents -- Chapter 1 - Topics and Purpose of this Book -- Chapter 2 - The Musculoskeletal System of a 28-week Human Trisomy 18 Cyclopia Fetus -- Chapter 3 - Comparative Anatomy of Muscular Anomalies in Trisomies 13, 18, and 21 -- Chapter 4 - Cyclopia, Trisomic Anomalies, and Order versus Chaos in Development and Evolution -- Chapter 5 - Digits and Muscles: Topology-Directed Muscle Attachment -- Chapter 6 - Evolutionary Mechanisms and Mouse Models for Down Syndrome -- Illustrations -- References -- Appendix A - Dissection Photographs of Trisomy 18 Human Cyclopia Fetus -- Appendix B - 3-D Renders of Trisomy 18 Human Cyclopia Fetus CT Scan Data -- About the Authors -- Color Plate Section -- Back Cover.

The first of its kind, this groundbreaking book utilizes data previously obtained to research the evolution of primates and applies it to humans. Completely unique in perspective, it analyzes the anatomy of the human body and its variations and defects and explores both their medical implications and their applications in an evolutionary-developmental (evo-devo) context. It specifically addresses both muscular and skeletal birth defects in human trisomy, and contains a detailed discussion of Down syndrome, one of the most studied human syndromes.

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Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.