Anesthesia and Perioperative Care for Organ Transplantation.

Intro -- Foreword I -- Foreword II -- Preface -- Contents -- Contributors -- Part I: General Topics -- 1: Ethical Considerations for Organ Transplantation -- Introduction -- What Is Ethics? -- Frameworks for Medical Ethics -- Organ Trafficking and Transplant Tourism -- Incentives for Organ Donors -- Altruistic Organ Donation -- Donation After Circulatory Determination of Death -- Allocation of Organs -- Conclusion -- References -- 2: Prevention of Perioperative Infections in Organ Transplant Recipients -- Introduction -- First Month After Transplant -- Between the Second and Sixth Months After Transplant -- From 6 Months After Transplantation and Beyond -- Surgical-Related Infections -- Kidney Transplantation -- SSIs -- Urinary Tract Infection (UTI) -- Recipient-Specific Factors -- Donor Allograft-Specific Factors -- Transplant Procedure-Related Factors -- Posttransplant Factors -- Antibiotic Prophylaxis -- Pancreas or Kidney-Pancreas Transplant -- SSIs -- Intra-abdominal Infections -- UTIs -- Bacteremias -- Antimicrobial Prophylaxis -- Liver Transplant -- SSIs -- Antimicrobial Prophylaxis -- Intestine or Multivisceral Transplant -- Bacteremia -- SSIs -- Antimicrobial Prophylaxis -- Heart Transplant -- Antimicrobial Prophylaxis -- Lung Transplant -- Tracheobronchitis and Endobronchial Infection -- Pneumonia -- SSIs -- Antimicrobial Prophylaxis -- Standard Prophylaxis Against Opportunistic Pathogens -- References -- 3: Donation After Cardiac Death -- Introduction -- Definitions -- The DCD Process and Donor Management -- Hospital Relations -- Donor Assessment -- Consents -- Surgical Technique -- Pre-mortem Administration of Pharmacologic Agents -- Operative Procedure -- DCD Abdominal Organ Utilization -- DCD Liver Transplantation -- Criteria for Acceptance -- Risks and Benefits of DCD Liver Transplantation -- Primary Nonfunction.

Hepatic Artery Thrombosis -- Biliary Complications -- Other Risks -- Outcomes of DCD Liver Transplantation -- Graft Survival and Retransplantation -- Patient Survival -- Rejection and Other Complications -- DCD Pancreas Transplantation -- Criteria for Acceptance -- Risks and Benefits of DCD Pancreas Transplantation -- Function of DCD Pancreas Transplants -- Long-Term Outcomes of the DCD Pancreas Transplants -- DCD Kidney Transplantation -- Criteria for Acceptance -- Risks and Benefits of DCD Kidney Transplantation -- Function of DCD Kidney Transplants -- Long-Term Outcomes of DCD Kidney Transplants -- Lung Transplantation from DCD Donation -- Conclusion -- References -- 4: Living-Related Organ Transplantations -- Introduction -- Ethical Issues of LROT -- Benefits and Disadvantages of Living Organ Donation -- Living Donor Kidney Transplantation -- Procedure of Living Kidney Donation -- Graft and Recipient Outcomes After Living Kidney Transplantation -- Living-Donor Liver Transplantation -- Living Liver Donation: Preoperative Evaluation -- Living Liver Donation: Procedure -- Recipient and Graft Outcomes After Living Liver Transplantation -- Living-Donor Lobar Lung Transplant -- Preoperative Evaluation of Donors -- Living Lung Donation: Procedure -- Recipient and Graft Outcomes After Living Lung Transplantation -- Living-Related Pancreas Transplantation -- Procedure -- Recipient Outcomes After Living Donor Pancreas Transplantation -- Conclusion -- References -- 5: Intensive Care of the Deceased Multiorgan Donor: One Donor, Nine Lives -- Introduction -- Pathophysiologic Changes During  Brain Death -- First Phase: Peri-Death -- Second Phase: Brain Stem Death -- Third Phase: Pathophysiologic and Homeostatic Changes After Brain Death -- Hemodynamics -- Cardiac Dysfunction -- Vasomotor Tone -- Volume Status -- Hormonal Changes -- Cortisol.

Antidiuretic Hormone -- Thyroid Hormone -- Insulin -- Coagulopathy -- Temperature Regulation -- Donor Management -- Hemodynamics -- Fluid -- Inotropes and Vasopressors -- Hormonal Therapy -- Cortisol -- Antidiuretic Hormone -- Thyroid Replacement -- Hyperglycemia -- Coagulopathy -- Hypothermia -- Ventilatory Management -- Organ-Specific Considerations -- Lungs -- Heart -- Liver -- Kidney -- Donation After Cardiac Death -- Conclusion -- References -- 6: Anesthetic Management of Donor Organ Retrieval in a Multiorgan Donor -- Introduction -- Multiorgan Donors -- Brain-Dead, Heart-Beating Donors -- DCD Donors -- The Process of Organ Retrieval -- Organ Retrieval in Brain-Dead, Heart-Beating Donors -- Organ Retrieval in DCD Donors -- Perioperative Management -- Maintaining Hemodynamic Stability -- Treating Endocrine Dysfunction -- Arginine Vasopressin -- Thyroid Hormone Replacement -- Corticosteroids -- Insulin -- Anesthetic Agents During Organ Procurement -- Treating Coagulopathy -- Ventilation Strategies -- Temperature Regulation -- Conclusion -- References -- Part II: Lung Transplantation -- 7: Preoperative Evaluation and Preparation for Lung Transplantation -- Introduction -- Indications for Lung Transplantation -- Candidate Selection -- Disease-Specific Guidelines for Candidate Selection and Listing -- Preoperative Evaluation -- Multidisciplinary Approach to Evaluation -- Lung Allocation Score -- Type of Lung Transplant -- Virtual Crossmatch -- Induction Strategies at the Time of Lung Transplantation -- Ventilatory and Hemodynamic Support -- Summary -- References -- 8: Bilateral Sequential Lung Transplantation: What the Anesthesiologist Needs to Know About the Surgical Approach -- Introduction -- Preoperative -- Intraoperative -- Postoperative -- Conclusions -- References -- 9: Anesthetic Management for Lung Transplantation -- Introduction.

Preoperative Evaluation -- Vascular Access and Monitors -- Induction -- Airway Management -- Positioning -- Transesophageal Echocardiography -- Pneumonectomy: Anesthesia Considerations -- Extracorporeal Support -- Hemodynamic Support and Fluid Therapy -- Mechanical Ventilation -- Permissive Hypercapnia -- Anesthetic Maintenance -- Temperature Management -- Graft Implantation and Reperfusion -- Postprocedure TEE -- Closure and Transport -- Special Conditions -- Cystic Fibrosis -- Connective Tissue Diseases and Other Uncommon Disorders -- Pain Management -- Primary Graft Dysfunction -- Conclusion -- References -- 10: Postoperative Critical Care of Lung Transplant Patients -- Introduction -- Critical Care Issues in the Post-Lung Transplant Patient -- Neurologic Complications in Lung Transplant Recipients -- Hyperammonemia Syndrome -- Postoperative Cardiovascular Complications in Lung Transplant Recipients -- Hypovolemia -- Atrial Fibrillation -- Right Ventricular (RV) Dysfunction -- Left Ventricular (LV) Dysfunction -- Cardiac Tamponade -- Acute Postoperative Respiratory Care of the Lung Transplant Patient -- Acute Respiratory Failure After Lung Transplantation -- Primary Graft Dysfunction/Severe Reperfusion Injury -- Acute Rejection -- Dynamic Lung Hyperinflation -- Noninfectious Airway Complications -- Acute Kidney Injury After Lung Transplantation -- Hematologic Complications After Lung Transplantation -- Thrombotic Thrombocytopenic Purpura (TTP)/Hemolytic-Uremic Syndrome (HUS) -- Heparin-Induced Thrombocytopenia/Thrombosis (HIT/T) -- Venous Thromboembolic Disease, Including DVT and PE (VTE) -- Gastrointestinal Complications After Lung Transplantation -- Perioperative Infectious Concerns -- Perioperative Immunosuppression -- Future Directions -- Summary -- References -- Part III: Heart Transplantation.

11: Heart Transplant Patient Selection and Preparation -- Introduction -- Indications for Cardiac Transplantation -- Cardiopulmonary Reserve Evaluation -- Contraindications to Cardiac Transplantation -- Relative Contraindications to Cardiac Transplantation -- Age -- Obesity -- Renal Insufficiency -- Diabetes -- Peripheral Vascular Disease -- Lung Disease -- Tobacco Use -- Substance Abuse -- Psychosocial Evaluation -- Immunocompatability Testing -- Serologies and Vaccinations -- Age-Appropriate Screening -- Ongoing Evaluation -- Final Decision Making in Organ Allocation -- Summary -- References -- 12: Surgical Techniques of Heart Transplantation and Heart-Lung Transplantation -- Introduction -- Heart Transplantation -- Isolated Donor Harvest for Heart Transplantation -- The Operation -- Heart Preservation, Preparation, and Transportation -- Combined Donor Harvest of the Heart and Lungs for Distinct Recipients -- Heart Implantation Technique: Primary Operation -- Before the Donor Heart Arrives -- After the Donor Heart Arrives -- Heart Implantation Technique: Reoperative Surgery -- Heart Implantation Technique: Bridged Patients -- Heart/Lung Transplantation -- Combined Heart and Lung Harvest for Heart-Lung Transplants -- The Operation -- Heart and Lung Preservation, Preparation, and Transportation -- Combined Heart and Lung Implantation: Primary Operation -- Combined Heart and Lung Implantation: Reoperative Surgery or Surgery in Potentially Hostile Pleural Space -- Summary -- References -- 13: Anesthetic Management of Cardiac Transplantation -- Introduction -- History of Heart Transplantation -- Evaluation and Listing of Patients for Heart Transplantation -- Pathophysiology of End-Stage Heart Failure -- Pharmacologic Therapy and Implications -- Preoperative Mechanical Circulatory Support -- Cardiac Implantable Electronic Devices (CIED).

Right Heart Function and Preoperative Pulmonary Hemodynamics.

Description based on publisher supplied metadata and other sources.

Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.