Optimization of Research and Clinical Applications for Combat-related Posttraumatic Stress Disorder (PTSD) : Progress Through Modern Translational Methodologies RUSH.

Intro -- OPTIMIZATION OF RESEARCH AND CLINICAL APPLICATIONS FOR COMBAT-RELATED POSTTRAUMATIC STRESS DISORDER (PTSD): PROGRESS THROUGH MODERN TRANSLATIONAL METHODOLOGIES -- OPTIMIZATION OF RESEARCH AND CLINICAL APPLICATIONS FOR COMBAT-RELATED POSTTRAUMATIC STRESS DISORDER (PTSD): PROGRESS THROUGH MODERN TRANSLATIONAL METHODOLOGIES -- CONTENTS -- ABSTRACT -- INTRODUCTION -- PTSD DIAGNOSTIC CRITERIA ANDTREATMENT OBJECTIVES -- FROM THE BENCH: TRANSLATIONAL RESEARCH -- Translational Research: Fear Potentiation and Fear Inhibition -- Translational Research: Conditioned Fear Extinction -- Translational Research: Animal Models of PTSD -- AT THE "BEDSIDE": ADVANCEMENTS INEXPOSURE THERAPY FOR PTSD -- At the "Bedside": Exposure Therapy -- At the "Bedside": Virtual Reality -- AT THE "BEDSIDE": ADVANCEMENTS IN PHARMACOLOGICAL INTERVENTIONS FOR PTSD -- At the "Bedside": Antipsychotics -- Risperidone -- At the "Bedside": Antipsychotics -- Olanzapine -- At the "Bedside": Anticonvulsants -- Valproic Acid -- Lamotrigine -- At the "Bedside": Adrenergic Inhibitors -- Prazosin -- From Bench to "Bedside:" Potential Pharmacotherapies for PTSD -- At the Bench: D-cycloserine (DCS) -- At the "Bedside": D-cycloserine -- Still at the "Bench": Cannabinoid Receptor (CB1) Agonists -- Still at the "Bench": Valproic Acid (VPA) -- From Bench to "Bedside": Pharmacologic Summary -- RISK VERSUS RESILIENCE FOR THE DEVELOPMENTOF PTSD FOLLOWING TRAUMA -- Potential Genetic Vulnerability Risk Factors -- Twin Studies -- Commonly Reported Genetic Variants -- Serotonin (5-HT) Transporter (SERT) -- FKBP5 -- Dopamine Beta-Hydroxylase -- Resilience Factors -- PTSD and Co-morbidity with Major Depressive Disorder: Common Genetic Liability -- Epigenetics -- FUTURE DIRECTIONS -- CONCLUSION -- REFERENCES -- INDEX.

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Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.