The Cutaneous Lymphoid Proliferations : A Comprehensive Textbook of Lymphocytic Infiltrates of the Skin.

Intro -- Titlepage -- Copyright -- Acknowledgments -- CHAPTER 1 Introduction to the Classification of Lymphoma -- Kiel Lukes-CollinsWorking Formulation classifications -- WHO, REAL, EORTC, and the Combined WHO/EORTC classifications -- Summary -- References -- Appendix: Definitions of key terms and techniques -- Plasma cell markers -- Natural killer cell-associated markers -- Cytotoxic protein markers -- B cell markers -- Myelomonocytic markers including dendritic cell markers -- Follicular dendritic cell markers -- Special techniques -- Summary of antibodies, clones, and dilutions -- CHAPTER 2 The Therapy of Cutaneous T Cell Lymphoma -- Introduction -- Diagnostic work-up and staging procedures -- CTCL therapies -- Goals of therapy in advanced-stage CTCL -- Extracorporeal photopheresis (ECP) -- Interferons -- Retinoids -- Immunotoxins -- Monoclonal antibodies -- Histone deacetylase inhibitors (HDACi) -- Antibody drug conjugates (ADC) -- Cytotoxic chemotherapy -- Investigational therapies -- TLR agonists and cytokines -- Allogeneic hematopoietic stem cell transplantation (allo-HSCT) -- References -- CHAPTER 3 Molecular Analysis in Cutaneous Lymphoid Proliferation -- Introduction -- Immunoglobulin and T cell receptor structure -- PCR design for determination of clonality -- Detection of PCR products for clonality -- Evaluation of results -- The value and utility of molecular diagnostics in primary cutaneous lymphomas -- Limitations of clonality assessment by PCR -- Case vignettes -- References -- CHAPTER 4 Benign Lymphocytic Infiltrates -- Introduction -- Spongiotic and eczematous dermatitis -- Other spongiotic/eczematous tissue reactions -- Other causes of subacute eczematous dermatitis -- Interface dermatitis: cell-poor vacuolar interface dermatitis -- Interface dermatitis: lichenoid pattern.

Diffuse and nodular lymphocytic dermal infiltrates without atypia -- Diffuse and nodular lymphocytic infiltrates associated with autoimmune disease -- References -- CHAPTER 5 Reactive Lymphomatoid Tissue Reactions Mimicking Cutaneous T and B Cell Lymphoma -- Lymphomatoid drug eruptions -- Molecular profile of lymphomatoid drug eruptions -- Pathogenetic basis of lymphomatoid drug reactions -- Reactive lymphomatoid lesions encountered in lesions of collagen vascular disease -- Angiomatous Variants of Pseudolymphoma -- Case vignettes -- References -- CHAPTER 6 Precursor Lesions of Cutaneous T Cell Lymphoma -- Cutaneous T cell lymphoid dyscrasia -- Large plaque parapsoriasis -- Hypopigmented interface T cell dyscrasia: a unique indolent T cell dyscrasia -- Pigmented purpuric dermatosis (PPD) -- Pityriasis lichenoides -- Idiopathic erythroderma (pre-Sézary syndrome) -- Syringolymphoid hyperplasia with alopecia -- Folliculotropic T cell lymphocytosis/pilotropic T cell dyscrasia -- Idiopathic follicular mucinosis/alopecia mucinosa -- Keratoderma-like T cell dyscrasia -- Atypical lymphocytic lobular panniculitis -- Case vignettes -- References -- CHAPTER 7 Marginal Zone Lymphoma and Other Related Post Germinal Center B Cell Lymphoproliferative Disorders of The Skin -- Marginal zone lymphoma -- Blastic marginal zone lymphoma -- Epidermotropic marginal zone lymphoma -- Castleman disease -- Primary cutaneous plasmacytoma -- Primary cutaneous light chain associated cutaneous amyloidosis -- Case vignettes -- References -- CHAPTER 8 Primary Cutaneous Follicle Center Cell Lymphoma -- Clinical features -- Pathology -- Phenotypic profile -- Molecular studies -- Pathogenesis -- Cytogenetics -- Case vignettes -- Additional molecular and cytogenetic study -- References.

CHAPTER 9 Primary Cutaneous Diffuse Large B Cell Lymphoma Including the Leg Type and Precursor B Cell Lymphoblastic Lymphoma -- Primary cutaneous diffuse large B cell lymphoma -- Systemic diffuse large B cell lymphomas with a propensity to involve the skin -- Case vignettes -- Additional light microscopic, phenotypic, molecular, cytogenetic studies -- References -- CHAPTER 10 Intravascular Lymphoma -- Clinical features -- Light microscopic findings -- Phenotypic profile -- Molecular and cytogenetic studies -- Pathogenesis -- Differential diagnosis -- Intravascular anaplastic large cell lymphoma -- Benign intravascular proliferations of histiocytes and reactive T cells -- Case vignette -- References -- CHAPTER 11 Cutaneous Mantle Cell Lymphoma -- Clinical features -- Light microscopic findings -- Phenotypic profile -- Molecular studies -- Cytogenetic profile -- Pathogenesis -- Case vignettes -- Additional molecular and cytogenetic studies -- References -- CHAPTER 12 Mycosis Fungoides and Sézary Syndrome -- Definition -- Mycosis fungoides -- Sézary syndrome and erythrodermic mycosis fungoides -- Large cell transformation of mycosis fungoides -- Extracutaneous involvement in mycosis fungoides -- Case vignettes -- References -- CHAPTER 13 Cd30-Positive Lymphoproliferative Disorders Including Lymphomatoid Papulosis, Borderline Cd30-Positive Lymphoproliferative Disease, Anaplastic Large Cell Lymphoma, and T-Cell-Rich Cd30-Positive Large B Cell Lymphoma -- Introduction -- Lymphomatoid papulosis -- CD8+ lymphomatoid papulosis, including the type D variant -- Type E lymphomatoid papulosis (Case vignette 15) -- Borderline CD30-positive lymphoproliferative disorders (type C LYP) (Case vignette 9) -- Lymphomatoid papulosis with a rearrangement on chromosome 6p25.3 -- Cutaneous anaplastic large cell lymphoma -- Small cell ALCL.

Additional unusual histologic variants of anaplastic large cell lymphoma -- Breast-implant-associated anaplastic large cell lymphoma -- Intravascular anaplastic large cell lymphoma -- Sarcomatoid anaplastic large cell lymphoma (Case vignette 14) -- CD30-positive large B cell lymphoma -- Case vignettes -- References -- CHAPTER 14 CD4+ peripheral T cell lymphoma, not otherwise specified, including primary cutaneous CD4+ small/medium-sized pleomorphic T cell lymphoma -- Introduction -- Primary cutaneous CD4+ small/medium-sized pleomorphic T cell lymphoma -- CD30-negative large cell T cell lymphoma -- Cutaneous follicular helper T cell lymphoma -- Overview of overall prognosis of primary cutaneous peripheral T cell lymphoma, unspecified -- Evolution of the nomenclature of primary cutaneous CD4+ small/medium-sized pleomorphic T cell lymphoma -- Case vignettes -- References -- CHAPTER 15 Subcutaneous Panniculitis-Like T Cell Lymphoma -- Clinical features -- Morphology -- Phenotype -- Molecular studies -- Differential diagnosis -- Case vignettes -- References -- CHAPTER 16 CD8 T Cell Lymphoproliferative Disease of the Skin -- Overview -- Introduction -- Classification of primary CD8+ cutaneous T cell lymphomas -- Histomorphology of primary cutaneous CD8+ T cell lymphoma: primary cutaneous aggressive epidermotropic CD8+ cytotoxic T cell lymphoma, and CD8+ variants of peripheral T cell lymphoma, NOS, including primary cutaneous CD8+ granulomatous T cell lymphoma -- CD8 variant of lymphomatoid papulosis and other related CD30-positive T cell lymphoproliferative disorders of CD8 subtype -- Light microscopic findings -- Indolent CD8 positive lymphoid proliferation of the face and other body sites including acral surfaces -- CD8 prolymphocytic leukemia -- CD8 pseudolymphoma related to underlying HIV disease -- Drug-associated CD8+ pseudolymphoma.

Actinic reticuloid as a unique form of CD8+ pseudolymphoma -- Case vignettes -- References -- CHAPTER 17 Nasal and Related Extranodal Natural Killer Cell/T Cell Lymphomas and Blastic Plasmacytoid Dendritic Cell Neoplasm -- Introduction -- Biology of NK and NK-like T cells -- NK/T-cell lymphoma -- Nasal NK/T cell lymphoma -- Nasal type NK/T cell lymphoma -- Aggressive NK cell lymphoma -- Role of Epstein-Barr virus in the evolution of NK/T cell lymphomas -- Blastic plasmacytoid dendritic cell neoplasm -- CD56-positive γ δ lymphoma involving the subcutaneous fat -- Chronic granular lymphocytosis/large granular cell leukemia -- Natural killer-like CD4+ T cell lymphoma -- EBV-associated NK/T cell lymphomas of the elderly -- Hydroa vaccineforme (HV)-like lymphoma -- Cutaneous intravascular NK T cell lymphoma -- Case vignettes -- References -- CHAPTER 18 Primary Cutaneous γ δ T Cell Lymphoma -- Introduction -- Case vignettes -- Additional supplemental figures -- References -- CHAPTER 19 Epstein-Barr Virus-Associated Lymphoproliferative Disease -- Introduction -- Hydroa vacciniforme-like EBV-associated T cell lymphoproliferative disease/mosquito bite hypersensitivity -- EBV+ cutaneous B cell lymphoproliferative disorder of the elderly (Case vignette 4, Figures 19.15, 19.16, 19.17, 19.18, 19.19, 19.20, and 19.21) -- EBV-associated mucocutaneous ulcer -- EBV + T cell lymphoproliferative disease of the elderly -- General principles regarding EBV-associated lymphomagenesis -- Pathogenetic link between EBV-associated B cell lymphoma and iatrogenic immune dysregulation related to either methotrexate or cyclosporine -- Case vignettes -- References -- CHAPTER 20 Hodgkin Lymphoma of the Skin -- Clinical features -- Subtypes of Hodgkin lymphoma -- Case vignettes -- References -- CHAPTER 21 Chronic Lymphocytic Leukemia of B Cell and T Cell Prolymphocytic Leukemia.

B cell chronic lymphocytic leukemia.

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Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.