Biological Clocks : Effects on Behavior, Health and Outlook.

Intro -- BIOLOGICAL CLOCKS: EFFECTS ON BEHAVIOR, HEALTH AND OUTLOOK -- BIOLOGICAL CLOCKS: EFFECTS ON BEHAVIOR, HEALTH AND OUTLOOK -- CONTENTS -- PREFACE -- Chapter 1 THE HUMAN BIOLOGICAL CLOCK: FROM GENES TO CHRONOTHERAPY -- ABSTRACT -- 1. INTRODUCTION -- 2. ORGANIZATION OF THE HUMAN SCN -- 2.1. Neuronal Organization -- 2.2. Functional Organization -- 2.3. Temporal Organization -- 2.4. Multioscillator Circadian System -- 3. MOLECULAR GENETICS OF CIRCADIAN TIMING -- 3.1. Clock Genes and the Suprachiasmatic Nucleus -- 3.2. Organizing Principles of Cellular Clocks -- 3.3. Clock Gene Expression Patterns -- 4. THE SCN-PINEAL COMPLEX -- 4.1. Circadian Timing -- 4.2. Seasonal Timing -- 5. BIOLOGICAL CLOCK AND AGING -- 5.1. Circadian Rhythmicity and Aging -- 5.2. Clock Genes and Aging -- 5.3. Suprachiasmatic Nucleus Dysfunction in Older People -- 5.4. Pineal Melatonin and Aging -- 5.5. Sex, Circadian Clock and Aging -- CONCLUSION -- REFERENCES -- Chapter 2 PHOTOSENSITIVITY A DISREGARDED ATTRIBUTE TO ANALYZE "PHOTOPERIODIC CLOCKS" -- ABSTRACT -- QUANTITATIVE VS. QUALITATIVE TIME MEASUREMENT -- Experimental Evidence for Two Unlinked Measurement Systems -- Photosensitivity, "Required Day Number," and Perception of Increasing Day Length -- Photosensitivity as an Experimental Instrument for Investigating Clock Mechanisms -- Two Unlinked Measurement Systems -- Evidence for the Model -- Perspective -- Geographic variation of the photoperiodic response -- Is Pieris brassicae an exception or a model for a general principle? -- REFERENCES -- Chapter 3 RESPIRATION RHYTHMIC AND QUALITY OF SLEEP TO THE TOTAL WELLNESS AND DEVELOPMENT OF A CHILD -- ABSTRACT -- INTRODUCTION -- SLEEP AND BREATHING -- Sleep Disturbances -- The Human Upper Airway -- Structure of the Upper Airway -- Factors that Affect the Upper Airway -- SLEEP APNEA AND HYPOPNEA.

Central Respiratory Events -- Obstructive Respiratory Events -- Mixed Respiratory Events -- Obstructed Upper Airway in Children -- INSTRUMENTATIONS OF SLEEP STUDIES -- Diagnostic Polysomnography -- EPIDEMIOLOGY AND NATURAL HISTORY OF DISEASES -- CURRENT DILEMMAS IN RESPIRATORY SLEEP STUDIES -- A Healthcare Provider's Perspective -- A Caregiver's Perspective -- A Child's Perspective -- CONCLUSIONS -- ACKNOWLEDGMENT -- REFERENCE -- Chapter 4 CIRCADIAN SLEEP-WAKE RHYTHMS IN PRETERM INFANTS -- ABSTRACT -- INTRODUCTION -- FETAL ENTRAINMENT -- NEONATAL ENTRAINMENT -- An Integrative Model for the Development of Circadian Sleep-Wake Rhythms in Preterm Infants -- Prematurity - A Unique Window to Study Preliminary Circadian Rhythm Development -- CNS Perinatal Susceptibility as a Risk Factor -- NICU Environment as a Risk Factor -- Birth Mode as a Risk Factor -- Prematurity as a Risk Factor -- The Development of Circadian Sleep-Wake Rhythm in Preterm Infants as a Factor of Parenting and Environmental Stimulation -- Effects of Touch Interventions for Preterm Infants on Sleep-Wake Circadian Rhythmicity -- CONCLUSION -- REFERENCES -- Chapter 5 INTERACTIONS BETWEEN THE CIRCADIAN AND THE IMMUNE SYSTEM: A FRAMEWORK FOR THE UNDERSTANDING OF DISEASE -- ABSTRACT -- INTRODUCTION -- Circadian Rhythms in the Immune System -- Circadian-Immune Cross-Talk -- Chronobiological Factors in Tumor Development -- Circadian Alterations Induced by Cancer -- Implications of Molecular Clock Components in Cancer -- CONCLUSION -- REFERENCES -- Chapter 6 CHRONOECOLOGY OF NEOTROPICAL PRIMATES: THE SPIDER MONKEY ATELES GEOFFROYI -- ABSTRACT -- INTRODUCTION -- CIRCADIAN RHYTHMS -- REST-ACTIVITY CYCLE IN AN AMERICAN PRIMATE, THE ATELES GEOFFROYI -- Determination of the Circadian Activity Rhythm of the A. geoffroyi: A Laboratory Experiment -- Motor activity.

Rest-Activity Rhythm of the A. geoffroyi in Semi-Captivity -- Astronomical variables -- Meteorological variables -- Lunar cycles -- Rest-Activity Rhythm of the A. geoffroyi in Out-Door Semi-Captivity -- Change of living conditions from outdoor captivity to an electrified fence enclosure in the natural environment: impact on the circadian rest-activity rhythm. -- Behavioral categories with daily temporal variation -- Behavior -- CONCLUSION -- THE FUTURE OF CHRONOECOLOGICAL RESEARCH -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 7 ON CLOCKS, CHAOS AND CANCER: A BIODYNAMIC APPROACH TO CANCER -- ABSTRACT -- Introduction -- Self-Organization: An Overview -- Clocks and Chaos -- The Master Clock and Cancer -- Bioenergetics, Evolution and Complexity: Back to the Beginning -- CONCLUSION -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 8 KLEPSYDRAIC MODEL OF INTERNAL TIME REPRESENTATION: EXPERIMENTAL FINDINGS AND ANALYTICAL PROPERTIES -- ABSTRACT -- INTRODUCTION -- INTERNAL TIME REPRESENTATION -- DUAL KLEPSYDRA MODEL -- Experimental Findings -- Analytical Properties -- Klepsydraic Clock and Klepsydraic Time-Scales -- Subjective Awareness of Duration and Temporal Order -- Directions of Further Research -- CONCLUSION -- ACKNOWLEDGMENTS -- REFERENCES -- INDEX.

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