Uric Acid : Biology, Functions and Diseases.

Intro -- URIC ACID: BIOLOGY, FUNCTIONS AND DISEASES -- URIC ACID: BIOLOGY, FUNCTIONS AND DISEASES -- Library of Congress Cataloging-in-Publication Data -- Contents -- Preface -- Chapter I: The Role of Uric Acid in the Avian Species -- Abstract -- Introduction -- Avian Mitochondria: Structure and ROS Production -- Mitochondrial Generation of ROS -- Avian Mitochondrial ROS Production -- Oxidative Stress -- The Evolutionary Loss of Uricase: Implications for Avian Longevity -- Xanthine Oxidoreductase:The Formation of Uric Acid -- XOR Chemistry and Structure -- Mammalian XOR Tissue Distribution -- Avian XOR Tissue Distribution -- Uric Acid in the Antioxidant Defense System -- Avian Renal Transport of Uric Acid -- Avian Gout -- Conclusion -- Acknowledgment -- References -- Chapter II: Uric Acid in Multiple Sclerosis and Neurodegenerative Diseases -- Abstract -- Introduction -- Oxidative Toxicity in Multiple Sclerosis -- Peroxynitrite -- Peroxynitrite in Multiple Sclerosis -- Uric Acid -- Uric Acid and Multiple Sclerosis -- Uric Acid and Neurodegenerative Diseases -- Conclusion -- References -- Chapter III: Role of Uric Acid in Metabolic Syndrome -- Abstract -- Introduction -- Uric Acid as a Predictor of the Development of Hypertension and Metabolic Syndrome -- Uric Acid as a Risk Factor of Cardiovascular Risk in Patients with Metabolic Syndrome -- Uric Acid and Inflammation in MS -- Uric Acid as a Component of the Antioxidant Defense System -- Relationship between Uric Acid, OxidativeStress and Endothelial Dysfunction -- Conclusion and Perspectives -- References -- Chapter IV: The Role of Serum Uric Acid in Hypertension and Renal Failure: Is a Marker or the Cause? -- Abstract -- Introduction -- Potential Impact of Uric Acid on Hypertension - Epidemiology -- Inter-Relationship of Uric Acid and Risk of Cardiovascular Diseases in Hypertension Subjects.

Renal Handling of Uric Acid -- Potential Impact of Uric Acid on Chronic Kidney Disease- Epidemiology -- The Role of Uric Acid in Chronic KidneyDisease Progression -- Potential Impact of Diuretic Use on Serum Uric Acid and Renal Function -- Summary -- References -- Chapter V: Uric Acid: Biology, Functions and Diseases -- Abstract -- Introduction -- Uric Acid Metabolism -- Uric Acid Disorders -- Conclusion -- References -- Chapter VI: Uric Acid, Urea and Creatinine: Implications for Patients with Diabetic Vascular Disease -- Abstract -- Introduction -- 1. UA Associated with Cardio-Metabolic Risk Factors -- 1.1. Obesity -- 1.2. Dyslipidemia -- 1.3. Hypertension -- 1.4. Insulin Resistance -- 1.5. UA and Its Changes with Pre-Diabetes and Type 2 Diabetes -- 2. Underlying Mechanisms of UA with CVD in Diabetes Patients -- 2.1. Antioxidant - Prooxidant UA Redox Shuttle -- 2.2. Serum UA and Inflammation -- 2.3. Endothelial Dysfunction -- 3. Prognostic Implications of Serum Creatinine, Urea and Uric Acid in Diabetic Patients -- Conclusion -- Reference -- Index.

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Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.