Breast Cancer : Diagnostic Imaging and Therapeutic Guidance.

Breast Cancer: Diagnostic Imaging and Therapeutic Guidance -- Title Page -- Copyright -- Contents -- Preface -- Contributors -- Abbreviations -- Part 1: Anatomy, Physiology, and Pathology of the Breast -- 1 Development, Anatomy, and Physiology of the Mammary Gland -- 1.1 Development -- 1.2 Anatomy -- 1.3 Physiology -- Bibliography -- 2 Tumor Formation -- 2.1 Mutation, Carcinogenesis, and Angiogenesis -- 2.2 Risk Factors -- 2.3 Genetic Risk Factors -- 2.4 Prevention -- 2.4.1 Primary Prevention -- 2.4.2 Secondary Prevention -- 2.4.3 Tertiary Prevention -- 2.5 Epidemiology, Incidence, and Mortality -- Bibliography -- 3 Pathology of Benign and Malignant Changes in the Breast -- 3.1 Benign Changes -- 3.1.1 Histological Principles -- 3.1.2 Nonneoplastic, Nonproliferative Diseases of the Breast -- 3.1.3 Benign Tumor-Forming Diseases -- 3.2 Malignant Changes in the Breast -- 3.2.1 Classification of Malignant Breast Tumors (WHO Classification, B-Categories) -- 3.2.2 Prognostic and Predictive Factors -- 3.2.3 Papillary Lesions -- 3.2.4 Ductal Carcinoma In Situ -- 3.2.5 Microinvasive and Invasive Breast Carcinoma -- 3.2.6 Tumors of the Nipple -- 3.2.7 Malignant Mesenchymal Tumors and Lymphomas of the Breast -- 3.2.8 Metastatic Tumors -- 3.3 Acknowledgments -- Bibliography -- Part 2: Breast Diagnostics -- 4 Nonimaging Diagnostics -- 4.1 History -- 4.2 Informed Consent -- 4.3 Self-Examination -- 4.4 Inspection -- 4.5 Palpation -- Bibliography -- 5 Mammography -- 5.1 Technique and Methods -- 5.1.1 Principles of X-ray Mammography -- 5.1.2 Components of a Mammography System -- 5.1.3 Exposure Parameters -- 5.1.4 Image Quality -- 5.1.5 Analog Mammography -- 5.1.6 Digital Mammography -- 5.1.7 Radiation Exposure -- 5.2 Parameters and Positioning -- 5.2.1 Standard Projections -- 5.2.2 Supplementary Views -- 5.2.3 Galactography -- 5.2.4 Mammography of the Male Breast.

5.2.5 Quality Assurance in Parameters and Positioning -- 5.3 Interpretation of Mammograms -- 5.3.1 Terminology -- 5.3.2 Tissue Density in a Mammogram According to the ACR BI-RADS Atlas -- 5.3.3 Interpretation Criteria -- 5.3.4 BI-RADS Classification of Mammography -- 5.3.5 Normal Findings in the Mammogram -- Bibliography -- 6 Breast Ultrasonography -- 6.1 Technique and Methods -- 6.1.1 Basic Principles -- 6.1.2 Device Adjustments -- 6.1.3 Examination Technique -- 6.1.4 Ultrasound Techniques -- 6.1.5 Quality Assurance -- 6.2 Evaluation -- 6.2.1 Terminology -- 6.2.2 Tissue Type in Sonography -- 6.2.3 Evaluation Criteria -- 6.2.4 BI-RADS Classification of Breast Ultrasonography -- 6.2.5 Normal Findings in Sonography -- Bibliography -- 7 Magnetic Resonance Imaging of the Breast -- 7.1 Technique and Methods -- 7.1.1 Basic Principles -- 7.1.2 Tumor Detection -- 7.1.3 Equipment -- 7.1.4 Timing of the Examination -- 7.1.5 Patient Positioning -- 7.1.6 Measurement Parameters -- 7.1.7 Image Postprocessing -- 7.1.8 Implant Evaluation -- 7.1.9 Nonestablished Examination Techniques -- 7.2 Evaluation -- 7.2.1 Terminology -- 7.2.2 Perfusion Pattern -- 7.2.3 Findings in the T1-Weighted Precontrast Image -- 7.2.4 Findings in the T2-Weighted Image -- 7.2.5 Findings in the T1-Weighted Contrast-Enhanced Image -- 7.2.6 Evaluation Criteria -- 7.2.7 BI-RADS Classification of MRI of the Breast -- 7.2.8 Normal Findings in MRI of the Breast -- Bibliography -- 8 Imaging of Breast Lesions -- 8.1 Benign Findings -- 8.1.1 Cysts -- 8.1.2 Inflamed Cysts -- 8.1.3 Complex Cysts -- 8.1.4 Myxoid Fibroadenoma -- 8.1.5 Fibrotic Fibroadenoma -- 8.1.6 Adenoma -- 8.1.7 Hamartoma -- 8.1.8 Lipoma -- 8.1.9 Mammary Fibrosis -- 8.1.10 Adenosis of the Breast -- 8.1.11 Fibrocystic Condition of the Breast -- 8.1.12 Adenomyoepithelioma -- 8.1.13 Acute Nonpuerperal Mastitis.

8.1.14 Chronic Nonpuerperal Mastitis -- 8.1.15 Intramammary Lymph Nodes -- 8.1.16 Pseudoangiomatous Stromal Hyperplasia -- 8.1.17 Seroma -- 8.1.18 Hematoma -- 8.1.19 Fat Necrosis (Oil Cyst) -- 8.1.20 Abscess -- 8.1.21 Postoperative Scars -- 8.2 Findings with Ambiguous Biological Potential -- 8.2.1 Papillomas -- 8.2.2 Radial Scars -- 8.2.3 Atypical Ductal Hyperplasia -- 8.2.4 Phyllodes Tumors -- 8.2.5 Cysts with Intracystic Proliferation -- 8.2.6 Lobular Intraepithelial Neoplasia -- 8.3 Intraductal Carcinoma -- 8.3.1 Ductal Carcinoma In Situ (Low Grade) -- 8.3.2 Ductal Carcinoma In Situ (Intermediate Type) -- 8.3.3 Ductal Carcinoma In Situ (High Grade) -- 8.4 Invasive Tumors -- 8.4.1 Invasive Ductal Carcinoma -- 8.4.2 Invasive Lobular Carcinoma -- 8.4.3 Tubular Carcinoma -- 8.4.4 Medullary Carcinoma -- 8.4.5 Mucinous Carcinoma -- 8.4.6 Invasive Papillary Carcinoma -- 8.4.7 Sarcomas -- 8.4.8 Triple-Negative Carcinoma -- 8.4.9 Paget's Disease of the Nipple -- 8.4.10 Inflammatory Carcinoma -- 8.4.11 Systemic Diseases Involving the Breast -- 9 Breast Intervention -- 9.1 Biopsy -- 9.1.1 Objective of Percutaneous Tissue Sampling -- 9.1.2 Percutaneous Tissue Sampling Equipment and Implementation -- 9.1.3 Interventional Imaging -- 9.1.4 Classification of Findings -- 9.1.5 Tumor Seeding and Mechanical Tumor Induction -- 9.1.6 Quality Assurance -- 9.2 Localization -- 9.2.1 Objective of Pretherapeutic Localization -- 9.2.2 Equipment and Implementation -- 9.2.3 Quality Assurance -- Bibliography -- Part 3: Prevention and Therapy of Breast Cancer -- 10 Examination Concepts -- 10.1 Prevention -- 10.2 Early Breast Cancer Detection (Secondary Prevention) -- 10.2.1 Mammography Screening -- 10.2.2 Individualized Examination Concepts -- 10.2.3 Early Detection inWomen with a High-Risk Profile -- 10.2.4 Future Concepts of Early Breast Cancer Detection.

10.3 Diagnostic Work-up -- 10.4 Pretherapeutic Local Staging -- 10.5 Pretherapeutic Peripheral Staging -- 10.6 Follow-up Care -- 10.7 Implant Evaluation -- 10.8 Evaluation of the Male Breast -- Bibliography -- 11 Surgical Treatment of Breast Carcinoma -- 11.1 Significance of Surgery in the Context of Multimodal Treatment of Breast Carcinoma -- 11.2 Types of Breast Carcinoma -- 11.2.1 Lesions of Uncertain Biological Potential (B3 Lesions) -- 11.2.2 Preinvasive Carcinoma (Ductal Carcinoma in Situ -- B5a) -- 11.2.3 Invasive Carcinoma (B5b) -- 11.3 Surgical Treatment of the Primary Lesion -- 11.3.1 Oncologic Aspects -- 11.3.2 Technical Aspects -- 11.4 Lymph Node Surgery -- 11.4.1 Procedure for Clinically Negative Node Status -- 11.4.2 Procedure for Clinically Positive Nodal Status -- 11.4.3 Procedure for Clinically Negative Node Status and Positive Sentinel Node -- 11.5 Secondary Breast Reconstruction -- 11.5.1 Timing the Reconstruction: Primary vs. Secondary Reconstruction -- 11.5.2 Alloplastic Reconstruction (Implant Reconstruction) -- 11.5.3 Autologous Reconstruction (Reconstruction Using Endogenous Tissue) -- 11.5.4 Nipple Reconstruction -- Bibliography -- 12 Medical Treatment of Breast Cancer -- 12.1 Basic Principles and Objectives -- 12.2 Adjuvant Drug Therapy -- 12.2.1 Adjuvant Chemotherapy -- 12.2.2 Neoadjuvant Therapy -- 12.2.3 Adjuvant Endocrine Therapy -- 12.2.4 Antibody Therapy -- 12.3 Medical Treatment in Locoregional Recurrence -- 12.4 Medical Treatment of Distant Metastases -- 12.4.1 Endocrine Therapy in Premenopausal Patients with Distant Metastases -- 12.4.2 Endocrine Therapy in Postmenopausal Patients with Distant Metastases -- 12.5 Endocrine Maintenance Therapy after Completing Chemotherapy -- 12.6 Chemotherapy of Metastatic Breast Cancer Combined with New Agents -- Bibliography -- 13 Radiotherapy of Breast Cancer.

13.1 Adjuvant Radiotherapy after Breast-Conserving Surgery -- 13.2 Adjuvant Radiotherapy after Mastectomy -- 13.3 Effectiveness of Adjuvant Radiation Therapy: Prognostic Factors -- 13.4 Integration of Adjuvant Radiotherapy into the Multimodal Treatment Concept -- 13.5 Target Volume and Dose Concept -- 13.5.1 Clinical Target Volume: Former Tumor Region, Mammary Gland, Chest Wall, and Regional Lymph Channels -- 13.5.2 Partial Breast Irradiation -- 13.5.3 Shortened Treatment Time: Alternative Fractionation Schemes -- 13.6 Acute Side Effects and Complications of Adjuvant Radiation Therapy -- 13.6.1 Acute Side Effects -- 13.6.2 Late Complications of Radiation Therapy -- 13.7 Planning and Implementing Radiation Therapy -- 13.8 Radiotherapy in Primarily Inoperable Tumors, Recurrences, and Metastatic Disease -- 13.9 Summary -- Bibliography -- 14 Management of a Diagnostic Breast Center -- 14.1 Expertise -- 14.2 Equipment -- 14.3 Facility Design -- 14.3.1 Doctor's Consultation Room -- 14.3.2 Mammography and Sonography Rooms -- 14.3.3 Breast MRI Room -- 14.3.4 Rooms for a Second Ultrasound Unit and for Interventional Procedures -- 14.3.5 Recovery Room -- 14.4 Ambiance -- 14.5 Communication -- 15 Logistics in an Interdisciplinary Breast Center -- 15.1 Background -- 15.2 Structure of a Certified Breast Center -- 15.3 Treatment Pathways in a Breast Center -- 15.4 Outlook -- Bibliography -- 16 Counseling Techniques and Psychosocial Support -- 16.1 Compliance -- 16.1.1 Quality of the Medical Services -- 16.1.2 General and Personal Requirements -- 16.1.3 Structural, Organizational, and Procedural Components -- 16.1.4 Interactive and Communicative Competence -- 16.2 Communication -- 16.2.1 General Principles of Communication -- 16.2.2 Communication: Dealing with the Patient -- 16.2.3 Communicating Results to the Patient.

16.3 The Patient's Flow through the Department.

Breast Cancer: Diagnostic Imaging and Therapeutic Guidance provides a concise, practical, and practice-based source of up-to-date diagnostic and therapeutic information for the general radiologist. In the diagnostic phase of evaluating breast disorders, the overriding consideration in the examination and assessment is to reduce false diagnoses to the absolute minimum-a principle wholly in the interests of the patient. The particular diagnostic pathway chosen will depend on the highly variable individual presentations and the associated findings. A major focus of the book is the comparative value of the various diagnostic imaging modalities. As well as discussing conventional mammography and adjunct modalities such as breast ultrasound and galactography, the text also showcases the superior utility of contrast-enhanced magnetic resonance imaging in providing the highest rate of detection of cancers at any stage. As well as radiological diagnosis, sections written by top specialists cover the interventional procedures for obtaining biopsies and also the surgical and medical therapy of breast carcinoma. Key Features: Combined authors' experience of more than 100 years provides this work with great depth and expertise. Richly illustrated with almost 600 images, including full color histology, patient photographs, and hundreds of radiological studies. BI-RADS classification for mammography, breast ultrasound, and breast MRI. Adjunct topics covered include screening and staging; lymph nodes; breast reconstruction; chemotherapy, also with respect to endocrine-active tumors; radiation therapy; tumors of the male breast; logistics in the breast care center; and psychosocial care. Breast Cancer: Diagnostic Imaging and Therapeutic Guidance is certain to prove an invaluable tool for all general radiologists involved in the evaluation and treatment of

patients with breast cancer.

Description based on publisher supplied metadata and other sources.

Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.