Pharmacogenetics of Breast Cancer : Towards the Individualization of Therapy.

Cover -- Half Title -- Title Page -- Copyright Page -- Preface -- Acknowledgments -- Table of Contents -- Contributors -- 1: Pharmacogenetics of Breast Cancer: Toward the Individualization of Therapy -- 2: Pharmacology, Pharmacogenetics, and Pharmacoepidemiology: Three P's of Individualized Therapy -- 3: Role of Genetic Variability in Breast Cancer Treatment Outcomes -- 4: The Role of Epigenetics in Breast Cancer: Implications for Diagnosis, Prognosis, and Treatment -- 5: Comparative Genomic Hybridization and Copy Number Abnormalities in Breast Cancer -- 6: Gene Expression Profiling as an Emerging Diagnostic Tool to Personalize Chemotherapy Selection for Early Stage Breast Cancer -- 7: Gene Expression-Based Predictors of Prognosis and Response to Chemotherapy in Breast Cancer -- 8: Utilization of Genomic Signatures for Personalized Treatment of Breast Cancer -- 9: Personalized Medicine by the Use of Microarray Gene Expression Profiling -- 10: Predictive Markers for Targeted Breast Cancer Treatment -- 11: Circulating Tumor Cells in Individualizing Breast Cancer Therapy -- 12: Individualization of Endocrine Therapy in Breast Cancer -- 13: TAILORx: Rationale for the Study Design -- 14: Taking Prognostic Signatures to the Clinic -- 15: Tissue is the Issue -- 16: Acquisition and Preservation of Tissue for Microarray Analysis -- 17: Tapping into the Formalin-Fixed Paraffin-Embedded (FFPE) Tissue Gold Mine for Individualization of Breast Cancer Treatment -- 18: Breast Cancer Stem Cells and Their Niche: Lethal Seeds in Lethal Soil -- 19: Molecular Imaging in Individualized Cancer Management -- 20: Cancer Nanotechnology for Molecular Profiling and Individualized Therapy -- Index.

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Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.