Solar-Energy-Absorbing Substances and Oxidative Stress and Inflammatory Diseases.

Intro -- Table of Contents -- Abstract -- Acknowledgments -- Introduction -- Scope and Limitations -- Chapter One -- A. Human Behavioral Practices with Sunscreen Applications. -- B. Urocanic Acid. Structure, Photochemistry, and Initiation of Immunosuppression in Humans -- C. Melanins: Structure and Photochemistry -- Chapter Two -- A. Allergic and Photoallergic Properties of Sunscreens -- B. Sunburn Effect, Erythema, and Photoaging -- C. Penetration of the Human Skin by UVA and UVB Radiations and Sunscreen Agents. -- D. DNA Damage Mediated by Ultraviolet Radiation. -- E. Glycation. -- F. The Ultraviolet Light Induced Impairments of Nucleic Acids, Immunity, Cancer Suppressor Gene P53, and Other Cell Protective Systems in the Human Skin. -- G. Cancerous Dermatologic Changes. Human Skin Cancers Induced by UV Radiation, Effects of Sunscreen Agents, Topical Applications of DNA Repair Enzymes, and Mechanisms of Anticancer Drugs -- Chapter Three -- A. General Aspects -- B. Various Quenching Processes -- C. Chemical Reactions of Photoexcited Molecules -- D. Excited States of Sunscreens and Their Reactions -- E. Photoinduced Electron-Transfer Processes of Excited Triplet States of Organic Substances in Reactions with Molecular Oxygen -- F. Photophysical and Photochemical Reactions of Organic Sunscreen Agents -- G. Photochemistry of Inorganic Agents -- Chapter Four -- A. Radiation-Induced Formation of Reactive Oxygen Species (ROS) -- B. Mechanisms of Hydrogen Peroxide Decomposition Reactions -- C. Properties of the Hydroxyl Radical -- D. Identification of Reactive Oxygen Species -- E. Nitroxyl (Aminoxyl) Radicals as Superoxide Dismutase Mimics -- F. Mechanisms of Autoxidations of Unsaturated Compounds and Reactions with Singlet Oxygen Species -- Chapter Five -- A. Enzymes -- B. Nonenzymatic Hydrophilic Antioxidants.

C. Nonenzymatic Lipid-Soluble Antioxidants -- Chapter Six -- Chapter Seven -- A. Evaluations of Vitamin E and Other Endogenous Antioxidants as Drugs against Various Diseases Including Cancers -- B. Evaluation of Aspirin™ and Other Nonsteroidal Anti-inflammatory Drugs as Anticancer Drugs -- Chapter Eight -- Chapter Nine -- Chapter Ten -- A. Skin Cancers -- B. Effects of Sunscreen Use -- Chapter Eleven -- Appendix 1.

This book explores various topics relevant to understanding the complexities of biological effects generated by solar radiation. Solar-energy-absorbing substances are evaluated, including sunscreen agents, and their influence on cancers and diseases. One assumption is the use of sunscreen agents cannot prevent the photoinitiation of biological system malfunction, such as immunosuppression. On the contrary, sunscreens can help enhance the negative solar-energy-induced effects, such as by skin penetration. This collection offers critical appraisals of clinical studies involving vitamins and nonsteroidal anti-inflammatory agents for alleviating, mitigating, or even curing of various inflammatory diseases including cancers.

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Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.