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The Essential Guide to Lithium Treatment.

By: Contributor(s): Material type: TextTextPublisher: Cham : Springer International Publishing AG, 2016Copyright date: ©2016Edition: 1st edDescription: 1 online resource (167 pages)Content type:
  • text
Media type:
  • computer
Carrier type:
  • online resource
ISBN:
  • 9783319312149
Subject(s): Genre/Form: Additional physical formats: Print version:: The Essential Guide to Lithium TreatmentDDC classification:
  • 616.891
LOC classification:
  • RC434.2-574
Online resources:
Contents:
Intro -- Preface -- Contents -- About the Authors -- 1: Diagnosis and Classification of Mood Disorders -- 1.1 Introduction -- 1.2 Symptoms of Mood Disorders -- 1.2.1 Symptoms of Depression -- 1.2.2 Symptoms of Mania and Hypomania -- 1.2.3 Symptoms of Mixed Episodes -- 1.3 Classification of Mood Disorders -- 1.3.1 Major Depressive Disorder -- 1.3.2 Bipolar Disorder -- 1.4 How Common Is Bipolar Disorder? -- 1.5 When Does Bipolar Disorder Start? -- 1.6 Why Is Bipolar Disorder So Difficult to Diagnose Precisely? -- References -- 2: Natural Course of Bipolar Disorder and Implications for Treatment -- 2.1 Introduction -- 2.2 Natural History of Bipolar Disorder -- 2.3 Polarity Dominance in Bipolar Disorder -- 2.4 Episodic Versus Chronic Nature of Bipolar Disorder -- 2.5 The Natural History of Rapid Cycling Bipolar Disorder -- 2.6 Stress and the Course of Bipolar Disorder -- 2.7 Functional Outcome in Bipolar Disorder -- 2.8 Quality of Life in Bipolar Individuals -- 2.9 Bipolar II Disorder -- 2.10 Suicide in Bipolar Disorder -- 2.11 Treatment Phases in Bipolar Disorder -- References -- 3: Lithium and Its History -- 3.1 What Is Lithium? -- 3.2 A Fascinating Element: Lithium's Discovery -- 3.3 Early Applications and the Breakthrough in Psychiatry -- 3.4 Lithium's Discovery: Also a History of Controversies -- 3.5 Position in Treatment Guidelines -- 3.6 Renaissance of Lithium Treatment? -- References -- 4: What Is Lithium and How Does It Work? -- 4.1 Chemistry of Lithium -- 4.2 Pharmacokinetic Properties of Lithium -- 4.3 The Principal Pharmacodynamic Actions of Lithium -- 4.3.1 Effects on Neurotransmitters -- 4.4 Pharmacogenetics of Lithium -- References -- 5: Maintenance Treatment with Lithium -- 5.1 Introduction -- 5.2 Goals of Maintenance and Long-Term Treatment -- 5.3 When Should Maintenance Treatment Be Started?.
5.4 Pharmacological Maintenance Treatment in Mood Disorders -- 5.5 Maintenance Treatment of Bipolar Disorder with Lithium -- 5.5.1 Initial Evidence and Landmark Studies -- 5.5.2 Growing Evidence for Lithium's Efficacy from Randomized Trials -- 5.5.3 The Recent Evidence from Meta-analyses -- 5.5.4 Predicting the Response to Lithium: How to Select the "Right" Person for Lithium Treatment? -- 5.5.5 Lithium in Offspring of Bipolar Parents -- 5.5.6 Lithium in Rapid Cycling -- 5.5.7 Discontinuing Lithium Long-Term Treatment -- 5.5.8 Does Lithium Treatment Lose Efficacy over Time in Long-­Term Treatment? -- 5.5.9 Does Lithium Treatment Lose Efficacy After Treatment Discontinuation? -- 5.5.10 Position of Lithium for Maintenance Treatment in Guidelines -- 5.6 Lithium Maintenance Treatment of Recurrent Unipolar Depression -- 5.7 How Can Lithium Maintenance Treatment Be Optimized? -- References -- 6: Treatment of Mania with Lithium -- 6.1 Introduction -- 6.2 Lithium as an Antimanic Medication: Recent Studies -- 6.3 Combination Studies with Lithium for Acute Mania -- 6.4 Meta-analyses of Antimanic Agents and Lithium -- 6.5 Predictors of Response to Lithium for Acute Mania -- 6.6 Lithium as a Treatment for Hypomania -- 6.7 Lithium's Place in Modern Practice and Treatment Guidelines in the Treatment of Acute Mania -- 6.8 Technical Aspects of Lithium Treatment During Acute Mania -- 6.9 Lithium Side Effects During Acute Treatment -- References -- 7: Treatment of Depression with Lithium -- 7.1 Introduction -- 7.2 Lithium's Efficacy as Monotherapy in Unipolar and Bipolar Depression -- 7.3 Lithium as an Adjunctive Antidepressant -- 7.4 Combination Treatments with Lithium -- 7.5 Lithium as an Antidepressant Accelerator -- 7.6 Predictors of Response to Lithium as an Antidepressant.
7.7 Lithium's Antidepressant Role in Treatment/Practice Guidelines -- 7.8 Techniques of Administration for Lithium's Use as an Antidepressant -- 7.9 Place of Lithium in the Treatment of Acute Depression -- References -- 8: Suicide Prevention with Lithium -- 8.1 Introduction -- 8.2 Evaluation of Suicidality -- 8.3 Treatment of Suicidality -- 8.4 Lithium Protection Against Suicide -- 8.4.1 How It All Started -- 8.4.2 Epidemiologically Based Evidence -- 8.4.3 Controlled Studies and Systematic Reviews -- 8.5 Lithium's Suicide-Preventing Effects: Clinical Implications -- 8.6 Suicide-Preventing Effects of Lithium as a Trace Element in Drinking Water -- 8.7 Does Lithium Also Reduce Acute Suicidal Ideation and Behavior? -- 8.8 Potential Mechanisms of Action in Lithium's Anti-­suicide Effects -- References -- 9: Neuroprotection and Other Clinical Indications of Lithium -- 9.1 Introduction -- 9.2 Lithium: Neurobiology of Neuroprotection -- 9.2.1 Neuroprotective and Cognitive Aspects of Lithium in Bipolar Disorder -- 9.2.2 Lithium and Neuroprotection in Dementia -- 9.3 Lithium in Other Central Nervous System Disorders (CNS) -- 9.3.1 Huntington's Disease (HD) -- 9.3.2 Amyotrophic Lateral Sclerosis (ALS) -- 9.3.3 Parkinson's Disease -- 9.3.4 Cluster Headache -- 9.4 Beyond Mood Disorders: Other Psychiatric Indications for Using Lithium -- 9.4.1 Schizophrenia and Schizoaffective Disorder -- 9.4.2 Obsessive-Compulsive Disorder and Pathological Gambling -- 9.5 Administering Lithium in Nonpsychiatric Disorders -- 9.5.1 Hyperthyroidism -- 9.5.2 Hematological Indications -- 9.5.3 Herpes Simplex -- 9.5.4 Seborrheic Dermatitis -- 9.5.5 Other Medical Conditions -- References -- 10: Lithium During Pregnancy and in the Postpartum Period -- 10.1 Introduction -- 10.2 Course of Bipolar Disorder During Pregnancy and the Postpartum Period.
10.3 Potential Effects of Lithium in Pregnancy -- 10.3.1 Lithium: Effects Related to Pregnancy and Its Course -- 10.3.2 Lithium and Fetal Malformations -- 10.3.3 Lithium and Neonatal Toxicity -- 10.3.4 Lithium and Developmental Abnormalities -- 10.4 Management of Lithium During Pregnancy and Delivery -- 10.5 Lithium, Breastfeeding, and the Postpartum Period -- 10.6 Clinical Decision-Making During Pregnancy for Women Taking Lithium -- 10.7 Other Mood Stabilizers During Pregnancy and Postpartum Periods -- References -- 11: Practical Management of Lithium -- 11.1 Introduction -- 11.2 Selection of Patients and Indications -- 11.3 Contraindications for Lithium Therapy -- 11.4 Drug Interactions with Lithium -- 11.5 Before Starting Lithium Treatment -- 11.6 How to Titrate Lithium? -- 11.7 Therapeutic Lithium Level -- 11.8 Monitoring During Lithium Treatment -- 11.9 Treating Lithium Intoxication -- 11.10 How to Withdraw Lithium -- 11.11 Common Mistakes in Lithium Treatment -- 11.12 Lithium During Special Circumstances -- 11.12.1 Lithium Therapy and Anesthesia -- 11.12.2 Combined Lithium and Electroconvulsive Therapy -- References -- 12: Adverse Effects of Lithium and Their Management -- 12.1 Introduction -- 12.2 Side Effects: Acute and Long Term -- 12.3 Long-Term Effects on Organ Systems -- 12.3.1 Lithium and Renal Function -- 12.3.2 Lithium and Thyroid Function -- 12.3.3 Lithium and Hyperparathyroidism -- 12.4 Lithium Toxicity -- References -- 13: Beyond Lithium: Other Treatments for Bipolar Disorder -- 13.1 Introduction -- 13.2 Treatment of Acute Mania -- 13.2.1 Second-Generation Antipsychotics -- 13.2.2 Anticonvulsants -- 13.2.3 Benzodiazepines -- 13.2.4 Combination Treatments -- 13.3 Treating Hypomania -- 13.4 Treatment-Resistant Mania -- 13.5 Other Treatments for Bipolar Depression.
13.5.1 First-Line Treatments for Bipolar Depression: Mood Stabilizers -- 13.5.2 Combination Treatments for Bipolar Depression -- 13.5.3 Antidepressants for Bipolar Depression -- 13.6 Treatment of Bipolar II Depression -- 13.7 Other Treatments for Bipolar Depression -- 13.8 Other Maintenance Treatments for Bipolar Disorder -- 13.8.1 Lamotrigine -- 13.8.2 Valproate -- 13.8.3 Second-Generation Antipsychotics -- 13.8.4 Carbamazepine -- 13.8.5 Other Agents -- 13.8.6 Medication Combinations -- References -- Index.
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Intro -- Preface -- Contents -- About the Authors -- 1: Diagnosis and Classification of Mood Disorders -- 1.1 Introduction -- 1.2 Symptoms of Mood Disorders -- 1.2.1 Symptoms of Depression -- 1.2.2 Symptoms of Mania and Hypomania -- 1.2.3 Symptoms of Mixed Episodes -- 1.3 Classification of Mood Disorders -- 1.3.1 Major Depressive Disorder -- 1.3.2 Bipolar Disorder -- 1.4 How Common Is Bipolar Disorder? -- 1.5 When Does Bipolar Disorder Start? -- 1.6 Why Is Bipolar Disorder So Difficult to Diagnose Precisely? -- References -- 2: Natural Course of Bipolar Disorder and Implications for Treatment -- 2.1 Introduction -- 2.2 Natural History of Bipolar Disorder -- 2.3 Polarity Dominance in Bipolar Disorder -- 2.4 Episodic Versus Chronic Nature of Bipolar Disorder -- 2.5 The Natural History of Rapid Cycling Bipolar Disorder -- 2.6 Stress and the Course of Bipolar Disorder -- 2.7 Functional Outcome in Bipolar Disorder -- 2.8 Quality of Life in Bipolar Individuals -- 2.9 Bipolar II Disorder -- 2.10 Suicide in Bipolar Disorder -- 2.11 Treatment Phases in Bipolar Disorder -- References -- 3: Lithium and Its History -- 3.1 What Is Lithium? -- 3.2 A Fascinating Element: Lithium's Discovery -- 3.3 Early Applications and the Breakthrough in Psychiatry -- 3.4 Lithium's Discovery: Also a History of Controversies -- 3.5 Position in Treatment Guidelines -- 3.6 Renaissance of Lithium Treatment? -- References -- 4: What Is Lithium and How Does It Work? -- 4.1 Chemistry of Lithium -- 4.2 Pharmacokinetic Properties of Lithium -- 4.3 The Principal Pharmacodynamic Actions of Lithium -- 4.3.1 Effects on Neurotransmitters -- 4.4 Pharmacogenetics of Lithium -- References -- 5: Maintenance Treatment with Lithium -- 5.1 Introduction -- 5.2 Goals of Maintenance and Long-Term Treatment -- 5.3 When Should Maintenance Treatment Be Started?.

5.4 Pharmacological Maintenance Treatment in Mood Disorders -- 5.5 Maintenance Treatment of Bipolar Disorder with Lithium -- 5.5.1 Initial Evidence and Landmark Studies -- 5.5.2 Growing Evidence for Lithium's Efficacy from Randomized Trials -- 5.5.3 The Recent Evidence from Meta-analyses -- 5.5.4 Predicting the Response to Lithium: How to Select the "Right" Person for Lithium Treatment? -- 5.5.5 Lithium in Offspring of Bipolar Parents -- 5.5.6 Lithium in Rapid Cycling -- 5.5.7 Discontinuing Lithium Long-Term Treatment -- 5.5.8 Does Lithium Treatment Lose Efficacy over Time in Long-­Term Treatment? -- 5.5.9 Does Lithium Treatment Lose Efficacy After Treatment Discontinuation? -- 5.5.10 Position of Lithium for Maintenance Treatment in Guidelines -- 5.6 Lithium Maintenance Treatment of Recurrent Unipolar Depression -- 5.7 How Can Lithium Maintenance Treatment Be Optimized? -- References -- 6: Treatment of Mania with Lithium -- 6.1 Introduction -- 6.2 Lithium as an Antimanic Medication: Recent Studies -- 6.3 Combination Studies with Lithium for Acute Mania -- 6.4 Meta-analyses of Antimanic Agents and Lithium -- 6.5 Predictors of Response to Lithium for Acute Mania -- 6.6 Lithium as a Treatment for Hypomania -- 6.7 Lithium's Place in Modern Practice and Treatment Guidelines in the Treatment of Acute Mania -- 6.8 Technical Aspects of Lithium Treatment During Acute Mania -- 6.9 Lithium Side Effects During Acute Treatment -- References -- 7: Treatment of Depression with Lithium -- 7.1 Introduction -- 7.2 Lithium's Efficacy as Monotherapy in Unipolar and Bipolar Depression -- 7.3 Lithium as an Adjunctive Antidepressant -- 7.4 Combination Treatments with Lithium -- 7.5 Lithium as an Antidepressant Accelerator -- 7.6 Predictors of Response to Lithium as an Antidepressant.

7.7 Lithium's Antidepressant Role in Treatment/Practice Guidelines -- 7.8 Techniques of Administration for Lithium's Use as an Antidepressant -- 7.9 Place of Lithium in the Treatment of Acute Depression -- References -- 8: Suicide Prevention with Lithium -- 8.1 Introduction -- 8.2 Evaluation of Suicidality -- 8.3 Treatment of Suicidality -- 8.4 Lithium Protection Against Suicide -- 8.4.1 How It All Started -- 8.4.2 Epidemiologically Based Evidence -- 8.4.3 Controlled Studies and Systematic Reviews -- 8.5 Lithium's Suicide-Preventing Effects: Clinical Implications -- 8.6 Suicide-Preventing Effects of Lithium as a Trace Element in Drinking Water -- 8.7 Does Lithium Also Reduce Acute Suicidal Ideation and Behavior? -- 8.8 Potential Mechanisms of Action in Lithium's Anti-­suicide Effects -- References -- 9: Neuroprotection and Other Clinical Indications of Lithium -- 9.1 Introduction -- 9.2 Lithium: Neurobiology of Neuroprotection -- 9.2.1 Neuroprotective and Cognitive Aspects of Lithium in Bipolar Disorder -- 9.2.2 Lithium and Neuroprotection in Dementia -- 9.3 Lithium in Other Central Nervous System Disorders (CNS) -- 9.3.1 Huntington's Disease (HD) -- 9.3.2 Amyotrophic Lateral Sclerosis (ALS) -- 9.3.3 Parkinson's Disease -- 9.3.4 Cluster Headache -- 9.4 Beyond Mood Disorders: Other Psychiatric Indications for Using Lithium -- 9.4.1 Schizophrenia and Schizoaffective Disorder -- 9.4.2 Obsessive-Compulsive Disorder and Pathological Gambling -- 9.5 Administering Lithium in Nonpsychiatric Disorders -- 9.5.1 Hyperthyroidism -- 9.5.2 Hematological Indications -- 9.5.3 Herpes Simplex -- 9.5.4 Seborrheic Dermatitis -- 9.5.5 Other Medical Conditions -- References -- 10: Lithium During Pregnancy and in the Postpartum Period -- 10.1 Introduction -- 10.2 Course of Bipolar Disorder During Pregnancy and the Postpartum Period.

10.3 Potential Effects of Lithium in Pregnancy -- 10.3.1 Lithium: Effects Related to Pregnancy and Its Course -- 10.3.2 Lithium and Fetal Malformations -- 10.3.3 Lithium and Neonatal Toxicity -- 10.3.4 Lithium and Developmental Abnormalities -- 10.4 Management of Lithium During Pregnancy and Delivery -- 10.5 Lithium, Breastfeeding, and the Postpartum Period -- 10.6 Clinical Decision-Making During Pregnancy for Women Taking Lithium -- 10.7 Other Mood Stabilizers During Pregnancy and Postpartum Periods -- References -- 11: Practical Management of Lithium -- 11.1 Introduction -- 11.2 Selection of Patients and Indications -- 11.3 Contraindications for Lithium Therapy -- 11.4 Drug Interactions with Lithium -- 11.5 Before Starting Lithium Treatment -- 11.6 How to Titrate Lithium? -- 11.7 Therapeutic Lithium Level -- 11.8 Monitoring During Lithium Treatment -- 11.9 Treating Lithium Intoxication -- 11.10 How to Withdraw Lithium -- 11.11 Common Mistakes in Lithium Treatment -- 11.12 Lithium During Special Circumstances -- 11.12.1 Lithium Therapy and Anesthesia -- 11.12.2 Combined Lithium and Electroconvulsive Therapy -- References -- 12: Adverse Effects of Lithium and Their Management -- 12.1 Introduction -- 12.2 Side Effects: Acute and Long Term -- 12.3 Long-Term Effects on Organ Systems -- 12.3.1 Lithium and Renal Function -- 12.3.2 Lithium and Thyroid Function -- 12.3.3 Lithium and Hyperparathyroidism -- 12.4 Lithium Toxicity -- References -- 13: Beyond Lithium: Other Treatments for Bipolar Disorder -- 13.1 Introduction -- 13.2 Treatment of Acute Mania -- 13.2.1 Second-Generation Antipsychotics -- 13.2.2 Anticonvulsants -- 13.2.3 Benzodiazepines -- 13.2.4 Combination Treatments -- 13.3 Treating Hypomania -- 13.4 Treatment-Resistant Mania -- 13.5 Other Treatments for Bipolar Depression.

13.5.1 First-Line Treatments for Bipolar Depression: Mood Stabilizers -- 13.5.2 Combination Treatments for Bipolar Depression -- 13.5.3 Antidepressants for Bipolar Depression -- 13.6 Treatment of Bipolar II Depression -- 13.7 Other Treatments for Bipolar Depression -- 13.8 Other Maintenance Treatments for Bipolar Disorder -- 13.8.1 Lamotrigine -- 13.8.2 Valproate -- 13.8.3 Second-Generation Antipsychotics -- 13.8.4 Carbamazepine -- 13.8.5 Other Agents -- 13.8.6 Medication Combinations -- References -- Index.

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Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.

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