Animal-Centric Care and Management : Enhancing Refinement in Biomedical Research.

Cover -- Half Title -- Title Page -- Copyright Page -- Table of Contents -- Preface -- Editors -- List of Contributors -- Chapter 1 Human-Animal Interactions -- Introduction -- Defining Human-Animal Interactions -- Impacts of Human-Animal Interactions -- Ecological Framework -- Animals -- Animal Welfare Theoretical Framework -- Harms for Animals -- Benefits for Animals -- Humans -- Human Theoretical Frameworks -- Harms for Humans -- Benefits for Humans -- Recommendations -- Principles -- Changing Human Behavior to Improve Animal Welfare -- Limitations and Future Work -- Conclusion -- References -- Chapter 2 A Culture of Care -- Background: Why a "Culture of Care?" -- What Is the Culture of Care? -- Implementing a Culture of Care -- The People Perspective -- The 3Rs Perspective -- The Good Science Perspective -- Methods and Tools to Shape a Culture -- The Role of Local Ethics or Animal Care and Use Committees -- Culture of Challenge -- Assessing the Culture of Care -- What Matters -- Surrogate Markers -- Building a Survey -- Assessing the Impact of the Culture of Care -- Promoting the Culture of Care -- National Meetings Arranged by Authorities -- Scientific Congresses and Meetings -- Organizations and Networks -- Other Opportunities to Promote the Culture of Care -- Conclusion -- References -- Chapter 3 Animal Emotions and Moods: Why They Matter -- Introduction -- Panksepp's Seven Core Emotions -- CARE -- GRIEF -- PLAY -- LUST -- SEEKING -- FEAR -- RAGE -- Summary of the Core Emotional Systems -- Core Affect Space -- Moods -- Welfare and Positioning in Core Affect Space -- Combining the Two Models of Emotion -- Conclusion -- References -- Chapter 4 Abnormal Behavior -- Abnormality -- Why We Should Care about Abnormal Behaviors -- Maladaptive or Malfunctional? -- Species Differences -- Abnormal Repetitive Behavior Prevention.

Abnormal Repetitive Behavior Treatment -- References -- Chapter 5 Animal Learning: The Science behind Animal Training -- Learning Theories -- Stimuli and Generalization -- Learning -- Non-Associative Learning -- Sensitization and Habituation -- Associative Learning -- Classical Conditioning -- The Effect of Salience and Context -- Extinction in Classical Conditioning -- Operant Conditioning -- Extinction in Operant Conditioning -- Schedules of Reinforcement -- Effect of Positive Reinforcement in Training -- Effect of Positive Punishment and Negative Reinforcement in Training -- References -- Chapter 6 Animal Training: The Practical Approach -- Introduction -- The ABC of Animal Training -- The Consequences of Behavior -- The Reinforcers -- The Aversives -- The Importance of Timing, Criteria, and Rate of Reinforcement -- Timing -- Criteria -- Rate of Reinforcement -- Getting the Behavior -- Capturing -- Targeting -- Luring and Baiting -- Shaping -- How to Get Started -- Incorrect Responses and Unwanted Behaviors -- Incorrect Responses -- Unwanted Behavior: Aggression, Frustration, and Fear -- Unwanted Behavior: Persistent or Progressing Incorrect Responding -- How to Deal with Incorrect Responses -- How to End a Session -- Creating a Balance -- Animal Training in Laboratory Animal Science: Challenges and Perspectives -- Acknowledgment -- References -- Chapter 7 The Zebrafish -- Introduction -- The Basics: Biological Health -- Environmental Conditions and Natural Behavior -- Zebrafish Life in the Wild -- Recreating the Natural Habitat in the Laboratory -- Psychological and Emotional Well-Being -- Special Considerations -- Strains -- Human-Animal Interaction -- Restrictive Types of Research -- Conclusion -- References -- Chapter 8 The Mouse -- The Animal -- Cognitive Abilities -- Emotions -- The Environment -- How to Enrich -- Practical Enrichments.

Handling -- Handling from the Animal's Perspective -- Handling from the Handler's Perspective -- Refining Mouse Handling in the Laboratory -- Practical Considerations for Non-Aversive Handling -- Standardizing Non-Aversive Handling in Research -- Further Considerations on Laboratory Mouse Welfare: Where Do We Go from Here? -- References -- Chapter 9 The Rat -- Introduction -- Free-Ranging Rats: Who Are They? -- Housing for Rats in Laboratories -- A Historical Perspective -- Current Knowledge -- Shelters -- Exercising and Mobility -- Complexity -- Recommendations for Implementation -- Relationships with Rats in Laboratories -- A Historical Perspective -- Current Knowledge -- Recommendations for Implementation -- Conclusion -- References -- Chapter 10 The Rabbit -- General Background -- Environment -- Social Needs -- Social Housing -- Handling -- Human-Animal Bond -- Training -- Conclusion -- Acknowledgments -- References -- Chapter 11 The Dog -- General Background -- Dog Senses and Cognition -- The Housing Environment -- Enrichment in the Dog Laboratory Facility -- Handling and Management -- Training -- Treating Dogs as Individuals -- Conclusion -- Acknowledgments -- References -- Chapter 12 The Non-Human Primate -- Introduction -- Basic Biology and Behavior -- Social Dynamics and Group Constellations -- Macaques -- Marmosets and Tamarins -- Social Housing of Primates in Captivity -- The Environment -- Foraging and Food Enrichment -- Socialization and Training -- References -- Chapter 13 The Pig -- The Pig -- Characterization: Morphology, Domestication, and Breeds -- The Biology and Natural Behavior of the Pig -- Cognitive and Emotional Abilities -- The Environment -- An Environment Designed for Comfort -- An Environment with Enrichment -- A Social Environment -- Behavioral Management (Handling, Habituation, and Training) -- Where to Go Next?.

References -- Index.

This book takes Russell and Burch's definition of Refinement as "elimination of inhumanities" and goes further. Rather than fitting animals into experimental conditions, it encourages readers to adjust conditions to better meet the behavioral, emotional, physical, and physiological needs and preferences of the animals.

Description based on publisher supplied metadata and other sources.

Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.