Pulmonary Hypertension : Pathogenesis, Diagnosis and Treatments.

Intro -- PULMONARY HYPERTENSIONPATHOGENESIS, DIAGNOSIS, AND TREATMENTS -- CARDIOLOGY RESEARCH AND CLINICAL DEVELOPMENTS -- PULMONARY HYPERTENSIONPATHOGENESIS, DIAGNOSIS, AND TREATMENTS -- Library of Congress Cataloging-in-Publication Data -- Contents -- Preface -- Editor's Affiliation -- CHAPTER 1. Pulmonary Hypertension: Pathogenesis, Diagnosis, and Treatments -- Abstract -- Introduction -- Pathogenic Mechanisms -- Cellular Mechanisms -- Smooth Muscle Cells and Fibroblasts -- Endothelial Cells -- Inflammatory Cells -- Platelets and Thrombosis -- Molecular Mechanisms -- Genetic Association -- Acquired/Exogenous Factors -- Vascular Effectors -- Diagnosis -- Screening -- ECG -- Chest X-ray -- Chest CT -- Echocardiography -- Magnetic Resonance Imaging -- Treatments -- General Measures and Supportive Therapy -- Calcium-Channel Blockers -- Anticoagulation -- Prostacyclin Therapy -- Prostacyclin Analogs -- Nitric Oxide -- Phosphodiesterase Type 5 inhibitors -- Endothelin -Receptorantagonists -- Combination Therapy -- Management of PH associated with Congenital Systemic-to-pulmonary Shunts and Eisenmenger's Syndrome -- Novel Speculative Therapies -- Rho-kinase Inhibitor: Fasudil -- PDGF Receptor Antagonist: Imatinib -- Simvastatin -- Ghrelin -- Bradykinin -- Fluoxetine -- Potassium Channel Augmentation -- Apoptosis Signal-Regulating Kinase 1 -- Peroxisome Proliferator-Activated Receptor Gamma -- Elastase Inhibitors -- Survivin -- Conclusion -- References -- CHAPTER 2. Possible Bridging to Final Repair in Eisenmenger Syndrome -- Abstract -- Background -- Pathophysiology of Eisenmenger Syndrome (ES) -- Evaluation of Operability -- Attempts to Increase Operability of ES Patients -- Medical Attempt -- Surgical Attempt -- #ASD -- (1) Shunt Closure with Preceding Targeted Therapies -- (2) Fenestrated ASD Occluder -- #VSD.

a. Pop-off Flap and Fenestrated Patch -- b. Pulmonary Artery Banding (PAB) -- #TGA/VSD -- a. Palliative Atrial Switch -- b. Arterial Switch -- Conclusion -- Reference -- CHAPTER 3. The Management of Congenital Systemic-to-Pulmonary Shunt and Advanced Pulmonary Artery Hypertension -- Abstract -- Background -- Methods and results -- Conclusion -- Abbreviations -- Patients and Methods -- Patients -- End Point -- Therapeutic Regimen -- Follow up -- Statistical Analysis -- Results -- The Results from the Whole Cohort of the 1212 Cases of Unmatched Patient -- The Results from the 245 Propensity-Matched Pairs -- The Results of Multivariate Logistic Regression and Cox Proportional Hazard Analysis for the Propensity-matched Patients -- Discussion -- Study Limitation -- References -- CHAPTER 4. Systemic Inflammatory Response Syndrome Associated with Pulmonary Endarterectomy in Patients with Chronic Thromboembolic Pulmonary Hypertension -- Abstract -- Background -- Material and Methods -- Results -- Conclusion -- Abbreviations -- Introduction -- Material and Methods -- Surgical Procedure -- Anesthetic Management -- Hemodynamic Status -- Cytokines, PCT and acute-phase proteins analysis -- Statistical Analysis -- Results -- Conclusion -- Acknowledgment -- References -- CHAPTER 5. Liver Transplantation and Pulmonary Hypertension -- Abstract -- Introduction -- Portopulmonary Hypertension -- Pathophysiology -- Presentation -- Screening -- Pharmacotherapy -- Staging of POPH: Risk Management -- Perioperative Management -- Acute Decompensated Pulmonary Hypertension -- Postoperative Care -- Conclusion -- References -- CHAPTER 6. Pulmonary Hypertension in the Down Syndrome Population -- Abstract -- Introduction -- References -- Index.

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Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.