Telomerase : Composition, Functions and Clinical Implications.

Intro -- TELOMERASE: COMPOSITION, FUNCTIONS AND CLINICAL IMPLICATIONS -- TELOMERASE COMPOSITION, FUNCTIONS AND CLINICAL IMPLICATIONS -- Library of Congress Cataloging-in-Publication Data -- Contents -- Preface -- Chapter I: Telomerase beyond Telomeres: New Roles for an Old Enzyme -- Abstract -- Introduction -- Non-Telomeric Functions of Telomerase -- Conclusion -- References -- Chapter II: Telomerase and Telomeric Proteins: A Life BeyondTelomeres -- Abstract -- Introduction -- Ectopic Tert Expression, Cellular Immortalization and Transformation -- Telomerase and Neoplasia -- Uncoupling a Pair: hTR and hTERT Play on Their Own -- TRF2 beyond Telomeres: Its Involvement in DNA Damage Response and Repair -- Conclusion -- Acknowledgments -- References -- Chapter III: Histone Deacetylase Inhibition as an Anticancer Telomerase-Targeting Strategy -- Abstract -- Introduction -- Summary and Perspectives -- References -- Chapter IV: Telomerase Rolein Pituitary Adenomas -- Abstract -- Telomerase in Pituitary Adenomas -- References -- Chapter V: Regulations of Telomerase Activity and WRN GeneExpression -- Abstract -- Introduction -- Conclusion -- Abbreviations -- References -- Chapter VI: Telomerase and Telomere Dynamics in Cancer: Clinical Application for Cancer Diagnosis -- Abstract -- Introduction -- Telomere and Telomerase in Cancer Development -- Detecting Methods of Human Telomerase/TERT in Clinical Materials of Human Cancers -- Telomerase/TERT for Cancer Diagnosis -- Telomerase/Tert Detection in Clinical Materials -- Conclusion -- Abbreviations -- References -- Index.

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Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.