Medical Care of Cancer Patients.

Half Title Page -- Title Page -- Copyright Page -- Section Editors -- Preface -- Contents -- Contributors -- 1 Introduction to the Care of the Cancer Patient -- 2 Mechanisms of Complications of Malignancy -- Fundamental Characteristics of Cancer -- Mechanisms of Organ Dysfunction in Cancer -- Compression, Obstruction, and Infiltration -- Systemic Effects -- Treatment-Related Effects -- Conclusions -- 3 Long-Term Consequences of Cancer Surgery -- Management of Lymphedema -- Endocrine and Exocrine Function after Pancreatectomy -- Postgastrectomy Syndromes -- Functional Complications of Esophageal Surgery -- Pelvic Operations -- 4 Collateral Damage Associated with Chemotherapy -- Systemic Toxic Effects -- Agents and Mechanisms of Action -- Chemotherapy-Induced Secondary Malignancies -- Fertility and Mutagenicity -- Appendix -- 5 Systemic Sequelae of Bioimmunotherapy -- Bioimmunotherapy Agents and Systemic Effects -- Conclusions -- 6 Ethical and Legal Issues in the Care of a Cancer Patient -- The Shift from Paternalism to Partnership -- Informed Consent: Process and Transparency -- Assessing Decisional Capacity -- Standards for Decision Making -- Advance Care Planning -- CPR and Do Not Resuscitate -- Confidant and Coordinator of Overall Care -- Physician-Internist as Confidant -- Family Secrets -- HIV and Communicable Diseases and the Duty to Warn -- Genetic Risks and the Results of Testing -- Risks to the Public -- Coordinator of Overall Care -- Internist as Gatekeeper -- Relationships with Consultants -- Alternative Medicine -- Terminating the Physician-Patient Relationship -- Conclusion -- 7 Cancer-Related Fatigue -- Clinical Manifestations -- Pathophysiology of CRF -- Fatigue-Associated Symptoms -- CRF Assessment Tools -- Evaluating the Patient with CRF -- Intervention in CRF -- Summary -- 8 Cancer Pain -- Definitions -- Models of Care.

Evaluation of the Patient with Cancer Pain -- Cancer Pain Syndromes -- Overcoming Obstacles in Cancer Pain Treatment -- Management of Chronic Cancer Pain -- Cancer Pain at the End of Life: Special Considerations -- Conclusion -- 9 Cancer and Depression: Phenomenology and Pathophysiology -- Clinical Manifestations -- Diagnosis -- Prevalence -- Risk Factors -- Mechanisms -- Summary -- 10 Sleep Disorders in the Cancer Patient -- Diagnosing Sleep Disturbance -- Specific Sleep Disorders in the Cancer Patient -- Chronobiology -- Chronotherapy -- Summary -- 11 Nausea -- Clinical Manifestations -- Pathophysiology -- Etiology -- Predictive Factors -- Diagnosis -- Treatment -- Treatment Guidelines for the Prevention of Acute and Delayed Emesis -- Special Emetic Problems -- Summary -- 12 Fever -- History -- Definitions -- Thermometric Variability -- Physiologic Variables -- Clinical Manifestations -- Pathophysiologic Mechanism -- Acute-Phase Changes -- Induction of the Acute-Phase Response -- Etiology -- 13 Imaging -- Paraneoplastic Syndromes -- Direct Medical Complications of the Cancer -- Indirect Medical Complications of the Cancer -- Systemic Complications of Malignancy and Therapy -- Chemotherapy-Induced Toxicity -- Radiation-Induced Toxicity -- Surgically Induced Conditions in Patients with Cancer -- Summary -- 14 Laboratory Investigation -- Cancer Center Laboratory -- Laboratory Issues in the Oncology Patient Population -- Summary -- 15 Risk Assessment and the Management of Neutropenia and Fever -- Historical Perspective -- Risk Assessment Strategies -- Epidemiology of Infection -- Risk-Based Therapy -- Antibiotic Therapy in Low-Risk Patients -- Hospital-Based Oral Antibiotic Therapy -- Early Discharge on Parenteral or Oral Antibiotics -- Ambulatory Management of the Entire Febrile Episode -- Risk-Based Therapy: General Issues.

Risk-Based Therapy: Advantages and Disadvantages -- Future Considerations -- Summary -- 16 Bacterial Infectious Disease Issues: Catheter-Related Infections -- Epidemiology and Impact -- Pathophysiology and Risk Factors -- Types of Intravascular Devices -- Manifestations and Definitions -- Diagnosis -- Preventive Strategies -- Management -- S. aureus -- 17 Viral Infections -- Viral Infections as causes of Cancer -- Viral Hepatitis -- Cytomegalovirus -- HIV/AIDS-Related Cancers -- Community-Acquired Respiratory Viruses -- Summary -- 18 Fungal Infections in Immunocompromised Hosts with Cancer -- Overview of Antifungal Agents -- Pathogenesis of Fungal Infections -- Candidiasis -- Aspergillosis -- Zygomycosis -- Fusariosis -- Trichosporonosis -- Overview of Endemic Mycoses and Cryptococcosis -- Empiric Antifungal Treatment -- Conclusions -- 19 Parasitic Disease Issues in Cancer Patients -- Pneumocystis jiroveci Infection -- Toxoplasma gondii Infection -- Miscellaneous Parasitic Infections -- 20 Mycobacterial Infections in Patients with Cancer -- Antimycobacterial Immune Defense -- Tuberculosis -- Nontuberculous Mycobacteriosis -- Summary -- 21 Hypercalcemia of Malignancy -- Symptoms of Hypercalcemia -- Humoral Mediators of Hypercalcemia of Malignancy -- Treatment of Hypercalcemia of Malignancy -- 22 Endocrine Paraneoplastic Syndromes -- Ectopic Adrenocorticotropic Hormone Syndrome -- Non-Islet Cell Tumor Hypoglycemia -- Syndrome of Inappropriate Antidiuretic Hormone -- Tumor-Induced Osteomalacia -- Ectopic GH-RH Syndrome -- Human Chorionic Gonadotropin Syndrome -- Miscellaneous Ectopic Paraneoplastic Syndromes -- 23 Endocrine Neoplastic Syndromes -- Hyperparathyroidism -- Calcitonin Syndrome -- Hormonal Syndromes Associated with Neuroendocrine Tumors -- 24 Diabetes and the Cancer Patient -- Diabetes and Cancer Outcomes -- Wound Healing and Diabetes.

Pathophysiology of Diabetes in Cancer -- Managing Diabetes in Patients with Cancer -- 25 Obesity and Cancer -- Obesity as a Risk Factor for Cancer -- Obesity after Cancer Therapy -- Hypothalamic Obesity due to Central Nervous System Insult -- Summary -- 26 Thyroid Disorders in Cancer Patients -- Physiology of the Hypothalamic-Pituitary-Thyroid Axis -- Hypothyroidism -- Thyrotoxicosis -- Thyroid Neoplasia -- 27 Pituitary and Adrenal Complications in Cancer Patients -- Hypothalamic-Pituitary Dysfunction -- Adrenal Diseases -- 28 Hypogonadism and Hormone Replacement in Men with Cancers -- Normal Physiology of the Hypothalamic-Pituitary-Gonadal Axis -- Differential Diagnosis of Hypogonadism in Cancer Patients -- Consequences and Clinical Manifestations of Hypogonadism -- Laboratory Diagnosis of Male Hypogonadism -- Treatment Options for Hypogonadal Men with Cancer -- Summary/Recommendations -- 29 Gastroesophageal Issues -- Esophageal Obstruction -- Gastric Outlet Obstruction -- Gastroesophageal Reflux after Esophagectomy -- Tube Gastrostomy -- 30 Hepatobiliary and Pancreatic Disorders -- Hepatobiliary Disorders -- Pancreatic Disorders -- Summary -- 31 Disorders of the Digestive Tract and Nutrition: Intestinal Issues -- Short Bowel Syndrome -- Malabsorption -- Nausea and Vomiting -- Constipation -- Diarrhea -- Summary -- 32 Graft versus Host Disease and the Immunologic Complications of Cancer -- Graft-versus-Host Disease -- Gastrointestinal GVHD -- Oral GVHD -- Hepatic GVHD -- Treatment for GVHD -- Other Tumor-Associated Immunologic Complications -- Autoantibodies -- Conclusions -- 33 Interventional Gastroenterology -- Endoscopic Ultrasonography -- Endoscopic Retrograde Cholangiopancreatography and Pancreatoscopy -- Endoscopic Mucosal Resection -- Endoscopic Ampullectomy -- Photodynamic Therapy -- Endoluminal Stenting.

Future in Interventional Gastroenterology -- 34 Nutritional Issues in Cancer Patients -- Dietary Factors and Cancer -- Genetics and Nutrition -- Current Dietary Recommendations -- Malnutrition and Cancer -- Etiology of Malnutrition -- Diagnosis of Malnutrition -- Treatment of Malnutrition -- Summary -- 35 Oral and Orofacial Considerations in Oncology -- Oral Complications -- Conclusions -- References -- 36 Upper Airway Problems -- Anatomy of the Upper Airway -- Clinical Manifestations of Upper Airway Problems -- Upper Airway Problems -- Diagnosis and Evaluation of Upper Airway Obstruction -- Management of Upper Airway Obstruction -- Summary -- 37 Pneumonia in Cancer Patients -- S. pneumoniae -- Legionella Species -- Gram-Negative Bacteria -- S. aureus -- Nocardia -- Cytomegalovirus -- Influenza Virus -- Respiratory Syncytial Virus -- Human Metapneumovirus -- Rhinovirus -- Aspergillus -- Fusarium -- Scedosporium -- Zygomycosis -- P. Carinii Pneumonia -- Mycobacterium tuberculosis -- Nontuberculous Mycobacteria -- Mycobacterium avium complex -- Rapidly Growing Mycobacteria -- Mycobacterium bovis -- 38 Noninfectious Pulmonary Problems in the Patient with Cancer -- Pleural Effusions in Cancer Patients -- Approach to Pneumothorax in Cancer Patients -- Cancer and Venous Thromboembolism -- Cancer and Hemoptysis -- Radiation-Induced Pneumonitis -- Chemotherapy-Related Lung Disease -- Conclusion -- 39 Cancer-Related Issues in Mechanical Ventilation -- Incidence of and Indications for MVS in Oncology Patients -- Airway Management -- Mechanical Ventilatory Support -- Outcomes of Cancer Patients Undergoing Mechanical Ventilation -- Noninvasive MVS -- Conclusions -- 40 Bronchoscopy and Lung Cancer: Diagnostic and Therapeutic Modalities -- History -- Bronchoscope -- Diagnostic Bronchoscopy -- Therapeutic Bronchoscopy -- Conclusion.

41 Direct Neurologic Complications of Cancer.

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Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.