Pancreatic Masses : Advances in Diagnosis and Therapy.

Intro -- Preface -- Contents -- Contributors -- Part I: Types of Lesions -- 1: Classification of Pancreatic Lesions -- Introduction -- Classification of Solid Exocrine Tumors of the Pancreas -- Ductal Adenocarcinoma -- Acinar Cell Carcinoma -- Other Uncommon Solid Pancreatic Tumors -- Classification of Cystic Exocrine Tumors of the Pancreas -- Serous Cystadenoma -- Intraductal Papillary Mucinous Neoplasm -- Mucinous Cystic Neoplasm -- Solid Pseudopapillary Neoplasm -- Classification of Pancreatic Ductal Precursor Lesions -- Classification of Pancreatic Neuroendocrine Tumors -- References -- 2: Pancreatic Adenocarcinoma -- Introduction -- Epidemiology -- Biology -- Risk Factors -- Inherited Risk Factors -- Environmental Risk Factors -- Clinical Presentation -- Serum Tumor Markers -- Pathology -- Staging -- Management -- Screening/Prevention -- Conclusion -- References -- 3: Less Common Solid Tumors of Pancreas -- Introduction -- Pancreatic Neuroendocrine Tumors -- Epidemiology -- Classification -- Functional PanNETs -- Nonfunctional PanNETs -- Functional PanNETs -- Diagnostic Approach -- Role of Biomarkers -- Radiologic Studies -- Arterial Stimulation Venous Sampling (ASVS) -- Grading and Staging System -- Staging Systems -- Solid Pseudopapillary Tumor -- Epidemiology -- Molecular Genetics -- Pathology -- Clinical Presentation and Diagnosis -- Acinar Cell Carcinoma -- Epidemiology -- Molecular Genetics -- Pathology -- Clinical Presentation and Diagnosis -- Primary Pancreatic Lymphoma -- Epidemiology -- Pathology -- Clinical Presentation and Diagnosis -- Pancreatoblastoma -- Epidemiology -- Pathology -- Clinical Presentation and Diagnosis -- Isolated Pancreatic Metastasis -- Epidemiology -- Pathology -- Clinical Presentation and Diagnosis -- References -- 4: Cystic Lesions of the Pancreas -- Introduction -- Mucinous Cystic Lesions of the Pancreas.

Intraductal Papillary-Mucinous Neoplasms -- Histopathologic Features -- Clinical Characteristics -- Radiological Findings -- EUS Morphology -- Mucinous Cystic Neoplasms -- Histopathologic Features -- Clinical Characteristics -- Radiological Findings -- EUS Morphology -- Nonmucinous Cystic Lesions of the Pancreas -- Serous Cystadenomas -- Histopathologic Features -- Clinical Characteristics -- Radiological Findings -- EUS Morphology -- Cystic Pancreatic Neuroendocrine Tumors -- Histopathologic Features -- Clinical Characteristics -- Radiological Findings -- EUS Morphology -- Solid Pseudopapillary Tumors of the Pancreas -- Histopathologic Features -- Clinical Characteristics -- Radiological Findings -- EUS Morphology -- Less Frequently Encountered Cystic Lesions of the Pancreas -- Conclusion -- References -- 5: Autoimmune Pancreatitis -- Introduction -- Etiology and Pathogenesis -- Pathology -- Macropathology -- Histopathology -- Epidemiology -- Clinical Picture -- Association with Other Autoimmune Diseases/Organ Involvement -- Diagnosis -- Laboratory Diagnostics -- Serology -- Imaging -- Classification and Diagnostic Criteria -- Therapy -- Natural Course and Prognosis -- References -- 6: Pancreatitis-Related Pancreatic Masses: Chronic Pancreatitis -- References -- Part II: Diagnosis -- 7: Radiographic Imaging -- Introduction -- Imaging Techniques -- Computed Tomography -- Magnetic Resonance Imaging -- Ultrasonography -- Nuclear Medicine -- Scintigraphy -- Positron Emission Tomography -- Hybrid Imaging -- Diagnostic Imaging Algorithm -- Imaging Features -- Solid Masses -- Cystic Masses -- Intraductal Papillary Mucinous Neoplasms -- References -- 8: EUS Imaging in the Diagnosis of Pancreatic Masses -- EUS Imaging Features of Solid Pancreatic Lesions -- Pancreatic Adenocarcinoma -- Pancreatic Neuroendocrine Tumors -- Diagnostic Role of EUS.

Accessory Spleen -- Mass-Forming Chronic Pancreatitis -- Autoimmune Pancreatitis -- Pancreatic Lymphoma -- Pancreatic Metastases -- EUS Imaging Features of Cystic Pancreatic Lesions -- Pseudocyst -- Serous Cystadenoma -- Mucinous Cystadenoma -- Intraductal Papillary Mucinous Neoplasm -- Solid Pseudopapillary Neoplasms -- EUS-Guided Needle-Based Confocal Laser Endomicroscopy -- References -- 9: Contrast-Enhanced EUS -- Introduction -- Technological Advances in Contrast-­Enhanced EUS -- Contrast-Enhanced EUS Using Fundamental B Mode -- Contrast-Enhanced Doppler EUS -- Contrast-Enhanced Harmonic EUS -- Principle and Ultrasound Contrast Agents of Contrast-Enhanced Harmonic EUS -- Principle -- Ultrasound Contrast Agents -- Contrast-Enhanced Doppler EUS for Pancreatic Masses -- Doppler Mode EUS Without Ultrasound Contrast Agents -- Doppler Mode EUS with Ultrasound Contrast Agents -- Contrast-Enhanced Harmonic EUS for Pancreatic Masses -- Enhancement Patterns -- Quantitative Analysis -- Comparison to Other Imaging Methods -- Relationship to EUS-FNA -- Contrast-Enhanced EUS for Staging -- T-Staging -- N-Staging -- Future Perspectives for Contrast-­Enhanced EUS -- Conclusions -- References -- 10: Endoscopic Ultrasonography: Role of EUS Sampling in Solid Pancreas Lesions -- Advantages -- Performance Where Other Methods Fail -- Small Lesions and Seeding -- Cost-Effectiveness and Safety -- Challenges and Solutions -- Training and the EUS Workforce -- Sampling Error and Rapid on-Site Cytology (ROSE) -- Decreased Sensitivity in Pancreatitis -- Neuroendocrine and Other Unusual Pancreas Masses -- Evolving Techniques and Tools -- Techniques -- Stylet and Suction -- Needle Size -- Core Biopsy for Histology -- Conclusions -- References -- 11: Endoscopic Ultrasonography: Role of EUS sampling in Cystic Lesions -- Introduction -- Gross Appearance of Fluid.

Biochemical Analyses of Pancreatic Fluid -- Carcinoembryonic Antigen -- Amylase -- Cytology -- DNA Analysis -- Novel Tests for Cyst-Type Differentiation -- Combination of Tests for Mucinous Differentiation -- Limitations of EUS-FNA and New Methods to Improve the Diagnostic Yield -- References -- 12: The Role of ERCP in Diagnosing Pancreatic Masses -- Introduction -- Indications for ERCP in Patients with Pancreatic Masses -- Description/Features of Cholangiograms and Pancreatograms in Pancreatic Masses -- Role of ERCP Brushings and Biopsies -- Cost-Effectiveness of ERCP in Diagnosis of PMasses -- Future of ERCP in Diagnosing Pancreatic Masses -- References -- 13: Endoscopic Retrograde Cholangiopancreatography (ERCP): Pancreatoscopy for the Evaluation of Pancreatic Neoplasia -- Peroral Pancreatoscopy Equipment and Technique -- Types of Pancreatoscopes -- Patient Preparation and Pancreatic Duct Access -- Technique Description -- Techniques to Improve Visualization -- Sampling Techniques -- Intraoperative Pancreatoscopy -- Adverse Events -- Pancreatic Carcinoma in situ -- Invasive Pancreatic Cancer -- Peroral Pancreatoscopy Findings in Patients with Pancreatic Cancer -- Intraductal Papillary Mucinous Neoplasia -- Pancreatoscopy Findings in Intraductal Papillary Mucinous Neoplasia -- Summary -- References -- 14: Recent Advances in Cytologic and Histologic Specimen Evaluation, FISH, and Molecular Markers -- Introduction -- Rapid Onsite Evaluation and Telecytology -- Pancreatobiliary Cytologic Nomenclature Update -- Ancillary Testing -- Summary -- References -- 15: Evaluation and Surveillance Strategies for Patients at Increased Risk of Pancreatic Cancer -- Introduction -- Epidemiology and Genetics -- Familial Pancreatic Cancer -- Pancreatic Cancer Associated with Inherited Cancer Syndromes -- Peutz-Jeghers Syndrome.

Familial Atypical Multiple Mole Melanoma -- Hereditary Breast and Ovarian Cancer Syndrome -- Lynch Syndrome -- Li-Fraumeni Syndrome -- Hereditary Pancreatitis -- Management of Individuals at Risk for Pancreatic Cancer -- Targets for Screening for Pancreatic Cancer -- Imaging -- Biomarkers -- Guidelines for Pancreatic Cancer Screening -- Management of Lesions Detected on Screening -- Surgery -- Conclusions -- References -- 16: Differential Diagnosis and Diagnostic Evaluation Algorithm -- Introduction -- Pancreatic Adenocarcinoma -- Chronic Pancreatitis -- Acute Pancreatitis -- Autoimmune Pancreatitis -- Cystic Pancreatic Tumors -- Rare Pancreatic Tumors -- Pancreatic Metastasis -- Other Diseases -- Diagnostic Algorithm for a Pancreatic Mass -- References -- Part III: Treatment: Solid Lesions and Cystic Lesions -- 17: Surgery for Solid Pancreatic Neoplasms -- Curative Surgery -- Role of Staging Laparoscopy -- Surgical Volume and Outcome -- Technical Details and Complications -- Minimally Invasive Surgery/Role of Robotic Technology -- Laparoscopic Pancreaticoduodenectomy -- Laparoscopic Distal Pancreatectomy with Splenectomy -- Role of Robotics -- Palliative Surgery -- Biliary Bypass -- Enteric Bypass -- References -- 18: Radiation Therapy for Pancreatic Cancer -- Radiation Therapy -- Radiation Therapy Techniques -- External-Beam Radiotherapy -- Particle Therapy -- Brachytherapy -- Intraoperative Radiotherapy -- Radiation Therapy for Malignant Pancreatic Neoplasms -- Postoperative Radiotherapy -- Preoperative Radiotherapy -- Definitive Radiotherapy -- Palliative Radiotherapy for Disseminated Malignancy -- Summary -- References -- 19: Chemotherapy -- Introduction -- Resectable Pancreatic Adenocarcinoma -- Adjuvant Therapy -- Neoadjuvant Therapy -- Advanced and Metastatic Pancreatic Adenocarcinoma -- Pancreatic Neuroendocrine Cancers.

Perioperative Medical Management.

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Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.