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Heart Disease in Children.

By: Contributor(s): Material type: TextTextSeries: Cardiology Research and Clinical DevelopmentsPublisher: Hauppauge : Nova Science Publishers, Incorporated, 2009Copyright date: ©2009Edition: 1st edDescription: 1 online resource (239 pages)Content type:
  • text
Media type:
  • computer
Carrier type:
  • online resource
ISBN:
  • 9781616682255
Subject(s): Genre/Form: Additional physical formats: Print version:: Heart Disease in ChildrenDDC classification:
  • 618.92/12
LOC classification:
  • RJ421 -- .H37 2009eb
Online resources:
Contents:
Intro -- HEART DISEASE IN CHILDREN -- HEART DISEASE IN CHILDREN -- Contents -- Preface -- Chapter I Congenital Primary Arrhythmias in Children -- Cardiac Channelopathies -- Long QT Syndrome (LQTS) -- LQT1 -- LQT2 -- LQT-3 -- LQT-4 -- LQT-5 -- LQT-6 -- LQT-7 -- LQT-8 -- LQT-9 and LQT-10 -- LQT-11 -- LQT-12 -- Acquired LQTS -- Electrocardiographic (ECG) Features in the Three Common Forms of Long QT Syndrome -- Genotype-Phenotype -- Intrauterine Death, Sudden Deaths in Infants, Children and Adolescents: Role of mutations in the Ion channel genes -- Diagnosis -- Clinical Management of LQTS -- Short QT Syndrome -- Brugada Syndrome -- Cardiac Conduction Defect or Lev-Lenègre Syndrome -- Sick Sinus Syndrome -- Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) -- Several Case Reports -- Case Reports-1 and 2 (LQT1): Figure 6 -- Case Report-3 (LQT2): Figure 7 -- Case Reports-4 and 5 (Autosomal Recessive Variant of LQT2): Figure 8 -- Note -- Case Report-6: Brugada Syndrome: Figure 9 -- Case Report-7: Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT): Figure 10 -- References -- Chapter II The Impact of Congenital Heart Disease on Brain Development and Neurodevelopmental Outcome -- Abstract -- Introduction -- 1. Preoperative Neurological Status in Babies with CHD -- 1.1. Clinical and Radiographic Evidence of Impaired Preoperative Neurological Status -- 1.2. Intrauterine Factors That Impact Cerebral Blood Flow and Neurodevelopment -- 1.2.1. In-Utero Cerebral Blood Flow Characteristics and Compensatory Mechanisms -- 1.2.2. Alterations in Cerebral Blood Flow in Fetuses with CHD -- 1.3. Congenital Brain and Developmental Abnormalities -- 1.4. Acquired Preoperative Brain Injury -- 2. Peri- and Intraoperative Neuroprotective Strategies -- 2.1. Intraoperative Factors That Impact Neurodevelopmental Outcome.
2.1.1. Acid-Base Strategies -- 2.1.2. Hemodilution during Bypass -- 2.1.3. Circulatory Arrest versus Low Flow Bypass -- 2.1.4. Emerging Surgical Techniques Designed to Preserve Cerebral Perfusion -- 2.2. Neuromonitoring Techniques -- 2.2.1. Transcranial Doppler (TCD) -- 2.2.2. Continuous Electroencephalography -- 2.2.3. Near Infrared Spectroscopy (NIRS) -- 2.2.4. Multi-Modal Neuromonitoring -- 2.3. Perioperative Critical Care -- 3. Neurodevelopmental Outcome after Surgical Repair of Congenital Heart Disease -- 3.1. Short-Term Neurological Outcome after Surgery -- 3.2 Neurodevelopmental Outcomes for Survivors at School Age and Beyond -- 3.2.1. Neurodevelopmental Outcomes in Children with Single Ventricles -- 3.2.2. Neurodevelopmental Outcomes in Children with Transposition of the Great Arteries -- Conclusions -- Acknowledgment -- References -- Chapter III PDA in the Preterm Infant -- Abstract -- Introduction -- Physiology and Pathophysiology of the Ductus Arteriosus -- Role of Prostaglandin in Ductal Regulation -- Role of Oxygen in Ductal Closure -- Anatomical Closure of the PDA -- Influence of Inflammation -- Haemodynamic and Clinical Effects of a PDA -- Pulmonary Effects of a PDA -- Cardiovascular and Systemic Effects of PDA -- Diagnosis of a PDA -- Clinical Diagnosis -- Echocardiographic Assessment of PDA -- Biochemical Assessment of PDA -- Natriuretic Peptides -- Physiology of BNP and NTpBNP -- The Role BNP and NTpBNP in the Management of PDA -- Cardiac Troponin T and PDA -- Management of the Preterm PDA -- Conservative Management of a PDA -- Medical Treatment of a PDA -- Prophylactic Treatment of a PDA -- Early Treatment of PDA -- Surgical Treatment of PDA -- Targeted Treatment of PDA: The Use of Echocardiography and Biochemical Markers -- Conclusion -- References -- Chapter IV Fetal Arrhythmias -- Abstract.
Normal Fetal Heart Rate and Overview of Fetal Arrhythmias -- Assessment of Fetal Rhythm -- Pathophysiologoy, Natural History and Management of Different Arrhythmias -- 1. Irregular Fetal Heart Rhythm -- 2. Fetal Tachycardias -- Pathophysiology -- Natural History -- Management -- 3. Fetal Bradycardias -- Pathophysiology -- Natural History -- Management -- Conclusion -- References -- Chapter V Pharmacological Therapy in Children with Congenital Long-QT Syndrome -- Abstract -- Introduction -- 1. β-blockers -- 1.1. Propranolol -- 1.2. Nadolol -- 1.3. Atenolol and Metoprolol -- 1.4. Carvedilol -- 2. Sodium Channel Blockers -- 2.1. Flecainide -- 2.2. Mexiletine -- 3. Potassium and Spironolactone -- 4. Calcium Channel Blockers -- Conclusions -- References -- Chapter VI Diagnostic Difficulties of Myocarditis in Children and Their Medico-Legal Aspects -- Abstract -- Introduction -- Epidemiology -- Etiology -- Clinical Symptoms -- Diagnostic Possibilities -- Differential Diagnosis -- Diagnostic Difficulties in Myocarditis -- Therapy and Prognosis -- Histopathology -- Forensic Evaluation -- References -- Chapter VII Apparent Life-Threatening Event (ALTE) and Wolff-Parkinson-White Syndrome: Is There a Connection? -- Abstract -- Introduction -- Case Report -- Conclusion -- References -- Chapter VIII Congenital Heart Disease and Necrotizing Enterocolitis -- References -- Chapter IX BMPR2 Sequence Analysis in a Down Syndrome Population with Congenital Heart Disease -- Abstract -- Introduction -- Methods -- Results -- Discussion -- Acknowledgments -- References -- Chapter X Arterial Duct Stenting in Congenital Heart Disease with Duct-Dependent Pulmonary Circulation -- Abstract -- Background -- Methods and Results -- Conclusions -- Introduction -- Arterial Duct Histology -- Physiology -- Percutaneous Palliation -- Historical Perspective.
Indication -- Contraindications -- Interventional Procedure -- Follow-Up -- Conclusions -- References -- Chapter XI Rare Reason for Myocardial Infarction in Adolescence: Anomalous Origin of the Left Main Coronary Artery in Association with Combined Prothrombotic Defects -- Abstract -- Abbreviations -- Introduction -- Case Report -- Discussion -- Conclusion -- References -- Index -- Blank Page.
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Intro -- HEART DISEASE IN CHILDREN -- HEART DISEASE IN CHILDREN -- Contents -- Preface -- Chapter I Congenital Primary Arrhythmias in Children -- Cardiac Channelopathies -- Long QT Syndrome (LQTS) -- LQT1 -- LQT2 -- LQT-3 -- LQT-4 -- LQT-5 -- LQT-6 -- LQT-7 -- LQT-8 -- LQT-9 and LQT-10 -- LQT-11 -- LQT-12 -- Acquired LQTS -- Electrocardiographic (ECG) Features in the Three Common Forms of Long QT Syndrome -- Genotype-Phenotype -- Intrauterine Death, Sudden Deaths in Infants, Children and Adolescents: Role of mutations in the Ion channel genes -- Diagnosis -- Clinical Management of LQTS -- Short QT Syndrome -- Brugada Syndrome -- Cardiac Conduction Defect or Lev-Lenègre Syndrome -- Sick Sinus Syndrome -- Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) -- Several Case Reports -- Case Reports-1 and 2 (LQT1): Figure 6 -- Case Report-3 (LQT2): Figure 7 -- Case Reports-4 and 5 (Autosomal Recessive Variant of LQT2): Figure 8 -- Note -- Case Report-6: Brugada Syndrome: Figure 9 -- Case Report-7: Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT): Figure 10 -- References -- Chapter II The Impact of Congenital Heart Disease on Brain Development and Neurodevelopmental Outcome -- Abstract -- Introduction -- 1. Preoperative Neurological Status in Babies with CHD -- 1.1. Clinical and Radiographic Evidence of Impaired Preoperative Neurological Status -- 1.2. Intrauterine Factors That Impact Cerebral Blood Flow and Neurodevelopment -- 1.2.1. In-Utero Cerebral Blood Flow Characteristics and Compensatory Mechanisms -- 1.2.2. Alterations in Cerebral Blood Flow in Fetuses with CHD -- 1.3. Congenital Brain and Developmental Abnormalities -- 1.4. Acquired Preoperative Brain Injury -- 2. Peri- and Intraoperative Neuroprotective Strategies -- 2.1. Intraoperative Factors That Impact Neurodevelopmental Outcome.

2.1.1. Acid-Base Strategies -- 2.1.2. Hemodilution during Bypass -- 2.1.3. Circulatory Arrest versus Low Flow Bypass -- 2.1.4. Emerging Surgical Techniques Designed to Preserve Cerebral Perfusion -- 2.2. Neuromonitoring Techniques -- 2.2.1. Transcranial Doppler (TCD) -- 2.2.2. Continuous Electroencephalography -- 2.2.3. Near Infrared Spectroscopy (NIRS) -- 2.2.4. Multi-Modal Neuromonitoring -- 2.3. Perioperative Critical Care -- 3. Neurodevelopmental Outcome after Surgical Repair of Congenital Heart Disease -- 3.1. Short-Term Neurological Outcome after Surgery -- 3.2 Neurodevelopmental Outcomes for Survivors at School Age and Beyond -- 3.2.1. Neurodevelopmental Outcomes in Children with Single Ventricles -- 3.2.2. Neurodevelopmental Outcomes in Children with Transposition of the Great Arteries -- Conclusions -- Acknowledgment -- References -- Chapter III PDA in the Preterm Infant -- Abstract -- Introduction -- Physiology and Pathophysiology of the Ductus Arteriosus -- Role of Prostaglandin in Ductal Regulation -- Role of Oxygen in Ductal Closure -- Anatomical Closure of the PDA -- Influence of Inflammation -- Haemodynamic and Clinical Effects of a PDA -- Pulmonary Effects of a PDA -- Cardiovascular and Systemic Effects of PDA -- Diagnosis of a PDA -- Clinical Diagnosis -- Echocardiographic Assessment of PDA -- Biochemical Assessment of PDA -- Natriuretic Peptides -- Physiology of BNP and NTpBNP -- The Role BNP and NTpBNP in the Management of PDA -- Cardiac Troponin T and PDA -- Management of the Preterm PDA -- Conservative Management of a PDA -- Medical Treatment of a PDA -- Prophylactic Treatment of a PDA -- Early Treatment of PDA -- Surgical Treatment of PDA -- Targeted Treatment of PDA: The Use of Echocardiography and Biochemical Markers -- Conclusion -- References -- Chapter IV Fetal Arrhythmias -- Abstract.

Normal Fetal Heart Rate and Overview of Fetal Arrhythmias -- Assessment of Fetal Rhythm -- Pathophysiologoy, Natural History and Management of Different Arrhythmias -- 1. Irregular Fetal Heart Rhythm -- 2. Fetal Tachycardias -- Pathophysiology -- Natural History -- Management -- 3. Fetal Bradycardias -- Pathophysiology -- Natural History -- Management -- Conclusion -- References -- Chapter V Pharmacological Therapy in Children with Congenital Long-QT Syndrome -- Abstract -- Introduction -- 1. β-blockers -- 1.1. Propranolol -- 1.2. Nadolol -- 1.3. Atenolol and Metoprolol -- 1.4. Carvedilol -- 2. Sodium Channel Blockers -- 2.1. Flecainide -- 2.2. Mexiletine -- 3. Potassium and Spironolactone -- 4. Calcium Channel Blockers -- Conclusions -- References -- Chapter VI Diagnostic Difficulties of Myocarditis in Children and Their Medico-Legal Aspects -- Abstract -- Introduction -- Epidemiology -- Etiology -- Clinical Symptoms -- Diagnostic Possibilities -- Differential Diagnosis -- Diagnostic Difficulties in Myocarditis -- Therapy and Prognosis -- Histopathology -- Forensic Evaluation -- References -- Chapter VII Apparent Life-Threatening Event (ALTE) and Wolff-Parkinson-White Syndrome: Is There a Connection? -- Abstract -- Introduction -- Case Report -- Conclusion -- References -- Chapter VIII Congenital Heart Disease and Necrotizing Enterocolitis -- References -- Chapter IX BMPR2 Sequence Analysis in a Down Syndrome Population with Congenital Heart Disease -- Abstract -- Introduction -- Methods -- Results -- Discussion -- Acknowledgments -- References -- Chapter X Arterial Duct Stenting in Congenital Heart Disease with Duct-Dependent Pulmonary Circulation -- Abstract -- Background -- Methods and Results -- Conclusions -- Introduction -- Arterial Duct Histology -- Physiology -- Percutaneous Palliation -- Historical Perspective.

Indication -- Contraindications -- Interventional Procedure -- Follow-Up -- Conclusions -- References -- Chapter XI Rare Reason for Myocardial Infarction in Adolescence: Anomalous Origin of the Left Main Coronary Artery in Association with Combined Prothrombotic Defects -- Abstract -- Abbreviations -- Introduction -- Case Report -- Discussion -- Conclusion -- References -- Index -- Blank Page.

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Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.

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