Rheumatoid Arthritis.

Rheumatoid Arthritis -- Contents -- Contributing Authors -- Foreword -- Preface -- Acknowledgments -- PART I Clinical, Laboratory, and Radiologic Features -- Epidemiology -- Clinical Features and Differential Diagnosis -- Prognosis and Clinical Course -- Self-Report Questionnaires in Clinical Care -- Clinical and Laboratory Measures -- Autoantibodies and Other Laboratory Tests -- Radiographic Findings -- Measurement of Radiologic Outcomes -- Ultrasonography and Magnetic Resonance Imaging for Diagnosis and Management -- PART II Pathogenesis -- Genetic Determinants -- Pathology -- Role of Cytokines -- Angiogenesis and Leukocyte Recruitment -- Neutrophils and Small Molecule Mediators -- Complement and Other Aspects of Innate Immunity -- T Cells in the Pathogenesis of Rheumatoid Arthritis -- Autoimmunity -- Immunosenescence and T-Cell Biology in Rheumatoid Arthritis -- Synovial Fibroblasts -- Cartilage and Bone Degradation -- Mechanisms of Joint Damage in Rheumatoid Arthritis -- Animal Models -- PART III Therapy -- Nonsteroidal Antiinflammatory Drugs and Analgesics -- Corticosteroids -- Methotrexate and Azathioprine -- Sulfasalazine -- Gold Compounds and Antimalarials -- Minocycline -- Cyclosporine -- Leflunomide -- Etanercept -- Antibodies to Tumor Necrosis Factor α: Infliximab and Adalimumab -- Anakinra (Interleukin-1 Receptor Antagonist) -- Staphylococcal Protein A Columns -- Combination Disease-Modifying Antirheumatic Drug Therapy -- Treatment of Early Disease -- Cognitive-Behavioral Therapy -- Physical Therapy -- Occupational Therapy -- Medical Aspects of Surgery -- Total Joint Arthroplasty -- Hand and Wrist Surgery -- Foot and Ankle Surgery -- Cervical Spine Surgery -- PART IV Special Management Issues -- Extraarticular Disease -- Pregnancy -- Osteoporosis -- Depression -- Appendixes.

APPENDIX A 1987 Revised Criteria for the Classification of Rheumatoid Arthritis (Traditional Format)* -- APPENDIX B American College of Rheumatology Preliminary Definition of Improvement in Rheumatoid Arthritis* -- APPENDIX C Paulus Criteria for Improvement of Patients with Rheumatoid Arthritis* -- APPENDIX D Disease Activity Score, Disease Activity Score 28, and European League Against Rheumatism Response Criteria* -- APPENDIX E Clinical Health Assessment Questionnaire -- APPENDIX F Clinical Health Assessment Questionnaire II -- Index.

This authoritative clinical reference provides comprehensive coverage of all aspects of rheumatoid arthritis. The basics of rheumatoid arthritis are thoroughly covered in order to provide a firm foundation for the main focus of the text: therapy and clinical management of the disease. Practitioners will find detailed information on both pharmacologic and nonpharmacologic courses of management, with special emphasis on the management of pain. More than 100 full-color illustrations provide clear visual support for the concepts in the text. Online references in each chapter, as well as an entire chapter on Web-based information resources, keep this book on the cutting edge of this rapidly evolving field.

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Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.