How We Remember : Brain Mechanisms of Episodic Memory.
- 1st ed.
- 1 online resource (383 pages)
- The MIT Press Series .
- The MIT Press Series .
Intro -- Contents -- Preface -- Chapter 1. Behavioral Dynamics of Episodic Memory -- Definition of Episodic Memory -- Episodic Memory as a Spatiotemporal Trajectory -- A Model of Episodic Memory -- Brain Systems for Episodic Memory -- Tests of Episodic Memory -- Functional Imaging Studies -- Episodic-like Memory in Animals -- Chapter 2. Neural Dynamics of Episodic Memory -- Anatomical Circuits for Episodic Memory -- Principles of Connectivity -- Cellular Mechanisms and Episodic Memory -- Network Oscillations -- Spiking Patterns -- Chapter 3. Coding of Space and Time for Episodic Memory -- Persistent Spiking Model -- Oscillatory Interference Model of Grid Cells -- Attractor Models of Grid Cells -- Biophysical Models of Entorhinal Cortex -- Hippocampal Place Cells Can Read and Store the Code -- Chapter 4. Encoding and Retrieval of Episodic Trajectories -- Encoding a Trajectory -- Retrieving a Trajectory -- Example of Trajectory Encoding and Retrieval -- Associations with Items or Events -- Theoretical Time Cells and Arc Length Cells -- Remembering Where You Parked Your Car -- Chapter 5. Linking Events and Episodes -- Hippocampal Circuits for Associations -- Function of Hippocampal Subregions -- Region CA3 Associative Memory -- Dentate Gyrus -- Region CA1 -- Full Hippocampal Models -- Chapter 6. Drug Effects on the Dynamics of Encoding and Retrieval -- Drug Effects on Human Memory -- Acetylcholine and Animal Memory -- Anatomy of Acetylcholine -- Physiological Effects of Acetylcholine -- Acetylcholine Enhances Encoding -- Encoding and Retrieval on Different Phases of Theta Rhythm -- Low Levels of Acetylcholine Allow Consolidation -- Chapter 7. Dynamics of Memory-Guided Behavior -- Behavior Guided by Trajectory Planning -- Behavior Guided by Gated Trajectory Replay -- Behavior Guided by Oscillatory Interference. Comparing Models of Theta Phase Precession -- Interaction of Memory Systems -- Stoichiometry of Memory Tasks -- Selection of Memory Actions -- Appendix: Mathematical Models of Memory -- Elements of the Episodic Memory Model -- Oscillations and Interference -- Grid Cell Model -- Associative Memory Function -- Implementation of Episodic Memory Model -- Acetylcholine Prevents Interference during Encoding -- Separation of Encoding and Retrieval on Phases of Theta Rhythm -- Simple Example of Attractor Dynamics -- Biophysical Simulations of Neuron Properties -- References -- Author Index -- Subject Index.
A novel perspective on the biological mechanisms of episodic memory, focusing on the encoding and retrieval of spatiotemporal trajectories.