TY  - BOOK
AU  - Gagnon,Aiden N.
TI  - Telomerase: Composition, Functions and Clinical Implications
T2  - DNA: Properties and Modifications, Functions and Interactions, Recombination and Applications
SN  - 9781617283390
AV  - QP606.T44 -- T447 2010eb 
U1  - 616.99/40642 
PY  - 2010///
CY  - Hauppauge
PB  - Nova Science Publishers, Incorporated
KW  - Telomerase
KW  - Electronic books
N1  - Intro -- TELOMERASE: COMPOSITION, FUNCTIONS AND CLINICAL IMPLICATIONS -- TELOMERASE COMPOSITION, FUNCTIONS AND CLINICAL IMPLICATIONS -- Library of Congress Cataloging-in-Publication Data -- Contents -- Preface -- Chapter I: Telomerase beyond Telomeres: New Roles for an Old Enzyme -- Abstract -- Introduction -- Non-Telomeric Functions of Telomerase -- Conclusion -- References -- Chapter II: Telomerase and Telomeric Proteins: A Life BeyondTelomeres -- Abstract -- Introduction -- Ectopic Tert Expression, Cellular Immortalization and Transformation -- Telomerase and Neoplasia -- Uncoupling a Pair: hTR and hTERT Play on Their Own -- TRF2 beyond Telomeres: Its Involvement in DNA Damage Response and Repair -- Conclusion -- Acknowledgments -- References -- Chapter III: Histone Deacetylase Inhibition as an Anticancer Telomerase-Targeting Strategy -- Abstract -- Introduction -- Summary and Perspectives -- References -- Chapter IV: Telomerase Rolein Pituitary Adenomas -- Abstract -- Telomerase in Pituitary Adenomas -- References -- Chapter V: Regulations of Telomerase Activity and WRN GeneExpression -- Abstract -- Introduction -- Conclusion -- Abbreviations -- References -- Chapter VI: Telomerase and Telomere Dynamics in Cancer: Clinical Application for Cancer Diagnosis -- Abstract -- Introduction -- Telomere and Telomerase in Cancer Development -- Detecting Methods of Human Telomerase/TERT in Clinical Materials of Human Cancers -- Telomerase/TERT for Cancer Diagnosis -- Telomerase/Tert Detection in Clinical Materials -- Conclusion -- Abbreviations -- References -- Index
UR  - https://ebookcentral.proquest.com/lib/orpp/detail.action?docID=3019872
ER  -