TY  - BOOK
AU  - Robles,Nicolás Roberto
TI  - Calcium Channel Blockers and Renal Disease
T2  - Cerebrovascular Research and Disorders
SN  - 9781612098678
AV  - RC903 -- .C25 2009eb 
U1  - 616.6/1061 
PY  - 2009///
CY  - New York
PB  - Nova Science Publishers, Incorporated
KW  - Kidneys -- Diseases -- Chemotherapy
KW  - Calcium -- Antagonists
KW  - Electronic books
N1  - Intro -- CALCIUM CHANNEL BLOCKERSAND RENAL DISEASE -- CALCIUM CHANNEL BLOCKERS AND RENAL DISEASE -- Contents -- Preface -- List of Authors -- Pharmacology of CalciumAntagonists -- Mechanisms of Action -- Differences among Calcium-Antagonists -- Clinical Pharmacology -- Pharmacokinetics -- Pharmacodynamics -- Tolerance -- Sympathetic Activation -- Ankle edema -- Other Untoward Effects -- Therapeutic Uses -- Hypertension -- Angina Pectoris -- Supraventricular Arrhythmias -- Subarachnoid Hemorrhage -- Myocardial Infarction -- Risk of Cancer -- Drug Interactions -- Special Considerations -- Older Patients -- Metabolic Syndrome -- Patients with Congestive Heart Failure -- Overdose of CCBs -- References -- Calcium Antagonists and SystemicHypertension -- Abstract -- Calcium Channel Blockers:The Findings of Clinical Trials -- Calcium Channel Blockers and Target OrganDisease -- 1. Calcium Channel Blockers and Arteriosclerosis -- 2. Use of Calcium Channel Antagonists in Coronary Disease(CHD) -- 3. Effects on Cerebrovascular Disease: Clinical Trials -- 4. Meta-Analysis on Cerebrovascular Outcomes -- Conclusions -- References -- Effects of Calcium Antagonists inRenal Hemodynamics -- Abstract -- 1. Ca2+ Channels and Vasoconstriction -- 1.1. Diversity of Ca2+ Channels -- 1.2. The Traditional Vision: The Role of L-Type Ca2+ Channels -- 1.3. The Emerging Evidences for Other Types of Ca2+ Channels -- 2. The Use of CCBs for BP Control inHypertension -- 2.1. The Principle of Ca2+ Antagonism -- 2.2. The Mechanism of "Ca2+ Antagonism" in Hypertension -- 3. Effects of CCBs on Microcirculation andRenal Hemodynamics -- 3.1. CCBs and Renal Protection -- 3.2. Mechanisms for Beneficial Renal Effects of New CCBs -- 3.2.1. DHP-Insensitive Ca2+ Channels in the Microcirculation andKidneys -- 3.2.2. DHP-Insensitive Ca2+ Channels in the Sympathetic Nerves; 3.2.3. New DHPs Cause New Effects on Renal Function -- 3.2.4. Limitations and Pertaining Questions -- Conclusion - Prospects -- References -- The Non-Hemodynamic Effects ofCalcium Channel Blockers on theKidney -- 1. Introduction -- 2. Antioxidant Effects -- 2.1. End-Stage Renal Disease -- 2.2. Diabetes -- 2.3. Effects of Associations -- 3. Effect on the Proliferation of MesangialCells -- 4. Effect on Fibrosis and Apoptosis -- 5. Other Effects -- Summary -- References -- Renoprotective Effect of CalciumAntagonists in SystemicHypertension -- Introduction -- Overview of Relevant Trials Regarding CCBsand Renal Protection in HypertensivePatients -- CCBs and Renal Protection in the Presenceof Preserved Renal Function -- Blood Pressure Control andNephroprotection in Patients withEstablished Chronic Kidney Disease -- Conclusions -- References -- Calcium Antagonists and RenalDisease -- Introduction -- Effects Calcium Channel Blockers on RenalHemodynamics -- Renoprotective Effect of CalciumAntagonists in Animals -- Effects on the Progression of Renal Injuryin Humans -- Calcium Antagonists versus Renin-Angiotensin Axis Blocking Drugs -- Calcium Antagonists versus Diuretics -- Comparison between Calcium-Antagonists -- New Calcium Antagonists -- Conclusion -- References -- Renal Ischaemia and CalciumChannel Blockers (CCBs) -- Introduction -- Chronic Renal Ischaemia -- Definition -- Pathogenic Mechanisms -- Epidemiology -- Morphology -- Clinical Presentation -- Calcium Channel Blockers and RID -- Contrast-Induced Nephropathy AND CCBs -- Risk Factors OF CIN -- Prevention of Radiocontrast Nephropathy -- References -- Calcium Antagonist after KidneyTransplantation -- Drug Treatment in Post-TransplantationArterial Hypertension -- References -- Non Dihydropyridinic CalciumAntagonists and Renal Disease; Nondihydropiridine Calcium ChannelBlockers vs Other Antihypertensive Agents -- Combination Therapy -- Conclusions -- References -- Index
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