TY  - BOOK
AU  - Chang,Huan-Cheng
AU  - Hsiao,Wesley Wei-Wen
AU  - Su,Meng-Chih
TI  - Fluorescent Nanodiamonds
SN  - 9781119477105
AV  - TP873.5.D5 .C436 2019 
PY  - 2018///
CY  - Newark
PB  - John Wiley & Sons, Incorporated
KW  - Nanostructured materials
KW  - Electronic books
N1  - Intro -- Title Page -- Copyright Page -- Contents -- Preface -- Acknowledgements -- Part I Basics -- Chapter 1 Introduction to Nanotechnology -- 1.1 Nanotechnology: From Large to Small -- 1.1.1 Feynman: Plenty of Room at the Bottom -- 1.1.2 Nanotechnology Today -- 1.1.3 The Bottom‐Up Approach -- 1.2 Nanocarbons: Now and Then -- 1.2.1 Classification -- 1.2.2 Fullerenes -- 1.2.3 Carbon Nanotubes -- 1.2.4 Graphenes -- References -- Chapter 2 Nanodiamonds -- 2.1 Ah, Diamonds, Eternal Beautiful -- 2.2 Diamonds: From Structure to Classification -- 2.2.1 Structure -- 2.3 Diamond Synthesis -- 2.3.1 HPHT -- 2.3.2 CVD -- 2.3.3 Detonation -- 2.4 Nanodiamonds: A Scientist's Best Friend -- References -- Chapter 3 Color Centers in Diamond -- 3.1 Nitrogen Impurities -- 3.2 Crystal Defects -- 3.3 Vacancy‐Related Color Centers -- 3.3.1 GR1 and ND1 -- 3.3.2 NV0 and NV− -- 3.3.3 H3 and N3 -- 3.3.4 SiV− -- 3.4 The NV− Center -- References -- Chapter 4 Surface Chemistry of Nanodiamonds -- 4.1 Functionalization -- 4.2 Bioconjugation -- 4.2.1 Noncovalent Conjugation -- 4.2.2 Covalent Conjugation -- 4.3 Encapsulation -- 4.3.1 Lipid Layers -- 4.3.2 Silica Shells -- References -- Chapter 5 Biocompatibility of Nanodiamonds -- 5.1 Biocompatibility Testing -- 5.1.1 Cytotoxicity -- 5.1.2 Genotoxicity -- 5.1.3 Hemocompatibility -- 5.2 In Vitro Studies -- 5.2.1 HPHT‐ND -- 5.2.2 DND -- 5.3 Ex Vivo Studies -- 5.4 In Vivo Studies -- References -- Part II Specific Topics -- Chapter 6 Producing Fluorescent Nanodiamonds -- 6.1 Production -- 6.1.1 Theoretical Simulations -- 6.1.2 Electron/Ion Irradiation -- 6.1.3 Size Reduction -- 6.2 Characterization -- 6.2.1 Fluorescence Intensity -- 6.2.2 Electron Spin Resonance -- 6.2.3 Fluorescence Lifetime -- 6.2.4 Magnetically Modulated Fluorescence -- References -- Chapter 7 Single Particle Detection and Tracking; 7.1 Single Particle Detection -- 7.1.1 Photostability -- 7.1.2 Spectroscopic Properties -- 7.1.3 Color Center Numbers -- 7.2 Single Particle Tracking -- 7.2.1 Tracking in Solution -- 7.2.2 Tracking in Cells -- 7.2.3 Tracking in Organisms -- References -- Chapter 8 Cell Labeling and Fluorescence Imaging -- 8.1 Cell Labeling -- 8.1.1 Nonspecific Labeling -- 8.1.2 Specific Labeling -- 8.2 Fluorescence Imaging -- 8.2.1 Epifluorescence and Confocal Fluorescence -- 8.2.2 Total Internal Reflection Fluorescence -- 8.2.3 Two‐Photon Excitation Fluorescence -- 8.2.4 Time‐Gated Fluorescence -- References -- Chapter 9 Cell Tracking and Deep Tissue Imaging -- 9.1 Cellular Uptake -- 9.1.1 Uptake Mechanism -- 9.1.2 Entrapment -- 9.1.3 Quantification -- 9.2 Cell Tracking -- 9.2.1 Tracking In Vitro -- 9.2.2 Tracking In Vivo -- 9.3 Deep Tissue Imaging -- 9.3.1 Wide‐Field Fluorescence Imaging -- 9.3.2 Optically Detected Magnetic Resonance Imaging -- 9.3.3 Time‐Gated Fluorescence Imaging -- 9.3.4 Magnetically Modulated Fluorescence Imaging -- References -- Chapter 10 Nanoscopic Imaging -- 10.1 Diffraction Barrier -- 10.2 Superresolution Fluorescence Imaging -- 10.2.1 Stimulated Emission Depletion Microscopy -- 10.2.2 Saturated Excitation Fluorescence Microscopy -- 10.2.3 Deterministic Emitter Switch Microscopy -- 10.2.4 Tip‐Enhanced Fluorescence Microscopy -- 10.3 Cathodoluminescence Imaging -- 10.4 Correlative Light‐Electron Microscopy -- References -- Chapter 11 Nanoscale Quantum Sensing -- 11.1 The Spin Hamiltonian -- 11.2 Temperature Sensing -- 11.2.1 Ultrahigh Precision Temperature Measurement -- 11.2.2 Time‐Resolved Nanothermometry -- 11.2.3 All‐Optical Luminescence Nanothermometry -- 11.2.4 Scanning Thermal Imaging -- 11.3 Magnetic Sensing -- 11.3.1 Continuous‐Wave Detection -- 11.3.2 Relaxometry -- References -- Chapter 12 Hybrid Fluorescent Nanodiamonds; 12.1 Silica/Diamond Nanohybrids -- 12.2 Gold/Diamond Nanohybrids -- 12.2.1 Photoluminescence Enhancement -- 12.2.2 Dual‐Modality Imaging -- 12.2.3 Hyperlocalized Hyperthermia -- 12.2.4 NV‐Based Nanothermometry -- 12.3 Silver/Diamond Nanohybrids -- 12.4 Iron Oxide/Diamond Nanohybrids -- 12.4.1 Single‐Domain Magnetization -- 12.4.2 Magnetic Resonance Imaging -- References -- Chapter 13 Nanodiamond‐Enabled Medicine -- 13.1 NDs as Therapeutic Carriers -- 13.2 Drug Delivery -- 13.2.1 Small Molecules -- 13.2.2 Proteins -- 13.3 Gene Therapy -- 13.3.1 RNA -- 13.3.2 DNA -- 13.4 Animal Experiments -- References -- Chapter 14 Diamonds in the Sky -- 14.1 Unidentified Infrared Emission -- 14.2 Extended Red Emission -- 14.3 Cosmic Events at Home on Earth -- References -- Further Reading -- Index -- EULA
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