TY  - BOOK
AU  - Schmiedel,Jö
TI  - The Role of MicroRNAs in Controlling Protein Expression Noise
SN  - 9783832588021
AV  - QH450 .S365 2016 
U1  - 572.865 
PY  - 2016///
CY  - Berlin
PB  - Logos Verlag Berlin
KW  - Gene expression
KW  - MicroRNA
KW  - Electronic books
N1  - Intro -- 1 Noise arising fromprotein production isminimized for noise-prone genes -- 1.1 Introduction -- 1.2 Results -- 2 microRNA control of protein expression noise -- 2.1 Introduction -- 2.2 Mathematical model of microRNA noise effects -- 2.3 Experimental validation of microRNA noise effects -- 2.3.1 Experimental validation of noise effects for miR-20a in mouse embryonic stem cells -- 2.3.2 Generality of intrinsic noise reduction for microRNAs and other post-transcriptional repressors -- 2.3.3 Additional extrinsic noise from individual and mixed microRNA pools -- 2.4 microRNA noise effects in endogenous target situations -- 2.5 microRNAs predominantly increase production ratios -- 2.6 Noise-sensitive genes are enriched for microRNA regulation -- 3 Conclusions and Outlook -- 3.1 Protein expression noise in mammalian cells -- 3.2 microRNA control of protein expression noise in mammalian cells -- 4 Materials &amp -- Methods -- 4.1 Bioinformatics -- 4.2 Experiments -- 4.3 Measuring fluorescent protein variability on a flow cytometry -- 4.4 GO Term microRNA regulation -- References
UR  - https://ebookcentral.proquest.com/lib/orpp/detail.action?docID=6032848
ER  -