TY  - BOOK
AU  - Sigel,Astrid
AU  - Sigel,Helmut
AU  - Freisinger,Eva
AU  - Sigel,Roland K.O.
AU  - Riddell,Imogen
AU  - Lippard,Stephen J.
AU  - Brabec,Victor
AU  - Kasparkova,Jana
AU  - Menon,Vijay
AU  - Farrell,Nicholas P.
TI  - Metallo-Drugs: Development and Action of Anticancer Agents
T2  - Metal Ions in Life Sciences Series
SN  - 9783110470734
AV  - RS431.A64 .S544 2018 
U1  - 615.7/98 
PY  - 2018///
CY  - Berlin/Boston
PB  - Walter de Gruyter GmbH
KW  - Antineoplastic agents
KW  - Electronic books
N1  - Intro -- About the Editors -- Historical Development and Perspectives of the Series -- Preface to Volume 18 -- Contents -- Contributors to Volume 18 -- Titles of Volumes 1-44 in the Metal Ions in Biological Systems Series -- Contents of Volumes in the Metal Ions in Life Sciences Series -- 1. Cisplatin and Oxaliplatin: Our Current Understanding of Their Actions -- 2. Polynuclear Platinum Complexes. Structural Diversity and DNA Binding -- 3. Platinum(IV) Prodrugs -- 4. Metalloglycomics -- 5. The Deceptively Similar Ruthenium(III) Drug Candidates KP1019 and NAMI-A Have Different Actions. What Did We Learn in the Past 30 Years? -- 6. Multinuclear Organometallic Ruthenium-Arene Complexes for Cancer Therapy -- 7. Medicinal Chemistry of Gold Anticancer Metallodrugs -- 8. Coordination Complexes of Titanium(IV) for Anticancer Therapy -- 9. Health Benefits of Vanadium and Its Potential as an Anticancer Agent -- 10 Gallium Complexes as Anticancer Drugs -- 11. Non-covalent Metallo-Drugs: Using Shape to Target DNA and RNA Junctions and Other Nucleic Acid Structures -- 12. Nucleic Acid Quadruplexes and Metallo-Drugs -- 13. Antitumor Metallodrugs that Target Proteins -- 14. Metallointercalators and Metalloinsertors: Structural Requirements for DNA Recognition and Anticancer Activity -- 15. Iron and Its Role in Cancer Defense: A Double-Edged Sword -- 16. Copper Complexes in Cancer Therapy -- 17. Targeting Zinc(II) Signalling to Prevent Cancer -- Subject Index
N2  - Metal Ions in Life Sciences links coordination chemistry and biochemistry in their widest sense and thus increases our understanding of the relationship between the chemistry of metals and life processes; in fact, it is an old wisdom that metals are indispensable for life. The series reflects the interdisciplinary nature of Biological Inorganic Chemistry and coordinates the efforts of scientists in numerous interconnecting research fields
UR  - https://ebookcentral.proquest.com/lib/orpp/detail.action?docID=5157376
ER  -