TY  - BOOK
AU  - Thachil,Jecko
AU  - Bagot,Catherine
TI  - Handbook of Venous Thromboembolism
SN  - 9781119095590
AV  - RC696.H363 2018 
U1  - 616.145 
PY  - 2018///
CY  - Newark
PB  - John Wiley & Sons, Incorporated
KW  - Thrombophlebitis
KW  - Electronic books
N1  - Intro -- Title Page -- Copyright Page -- Contents -- List of Contributors -- Foreword -- Section I Clinical Overview -- Chapter 1 Risk Factors for Venous Thromboembolism -- Introduction -- Previous VTE -- Surgery -- Hospitalised Medical Patients -- Cancer Associated Thrombosis (CAT) -- Pregnancy -- Combined Oral Contraceptive Use -- Family History of VTE and Thrombophilia -- Obesity -- Travel -- Substance Abuse -- Conclusion -- Further Reading -- Chapter 2 Management of Venous Thrombosis in the Lower Limbs -- Introduction -- Diagnosis -- Treatment -- Further Reading -- Chapter 3 Clinical Presentation of Acute Pulmonary Embolism -- Introduction -- Symptoms of Acute PE -- Clinical Signs of Acute PE -- Differential Diagnosis -- Clinical Presentation in Specific Patient Subgroups -- Clinical Presentation and Associated Prognosis -- Summary -- Further Reading -- Section II Diagnosis -- Chapter 4 Clinical Prediction Scores -- Pulmonary Embolism -- Deep Vein Thrombosis -- Potential Pitfalls -- Key Reading -- Chapter 5 Laboratory Aspects in Diagnosis and Management of Venous Thromboembolism -- Introduction -- Laboratory Diagnostics of Venous Thromboembolism -- Laboratory Prediction of Recurrent Venous Thromboembolism -- Laboratory Monitoring of Anticoagulant Therapy -- References -- Chapter 6 Thrombophilia Testing -- Inherited Risk Factors -- Acquired Risk Factors -- Mixed Risk Factors -- Indications for Thrombophilia Testing -- Key Points -- Further Reading -- Chapter 7 Radiological Diagnosis of Pulmonary Embolism -- Introduction -- Ventilation-perfusion Scanning (V/Q Scintigraphy) -- Spiral Computed Tomography Pulmonary Angiography (CTPA) -- The Issue of Subsegmental PE -- Haemodynamic Assessment of Patients with PE -- Latest Trends -- Cost-effectiveness -- Summary -- References -- Chapter 8 The Antiphospholipid Syndrome; Antiphospholipid Antibodies: Epidemiology and Antigenic Specificities -- Thrombosis -- Management of APS -- Management of Pregnancy -- Management of Catastrophic APS -- Review Articles -- Guidelines -- References -- Section III Treatment -- Chapter 9 Inpatient or Outpatient Anticoagulation -- Introduction -- Deep Vein Thrombosis -- Pulmonary Embolism -- Sub-segmental Pulmonary Embolism -- The Importance of a VTE Clinic -- Cost-effectiveness -- Summary -- Further Reading -- Chapter 10 An Anticoagulant Service in Practice -- History -- Current Organisation -- Referral Process -- Induction Appointments -- Hospital Discharge Patients -- Anticoagulant Clinic Structure -- Self-testing Patients -- Direct Oral Anticoagulants (DOACs) -- The Future of GCAS -- Further Reading -- Chapter 11 Point of Care Testing -- International Normalised Ratio (INR) -- Quality Control -- Comparison with Laboratory Results -- Limitations of POC devices -- POC D-dimer tests -- Key Learning for POC INR Testing -- Further Reading -- Chapter 12 Direct Oral Anticoagulants in the Prevention and Management of Venous Thromboembolism -- DOACs in treatment and prevention of Venous Thromboembolism: Introduction -- Oral Direct Thrombin Inhibitors -- Oral Xa Inhibitors -- Systematic reviews and meta‐analyses of DOACs -- Practical Issues for DOAC Usage -- DOAC use in Specific Patient Subgroups -- Further Reading -- Chapter 13 The Role of Thrombolysis in the Management of Venous Thromboembolism -- Introduction -- Rationale Behind CDT for Acute DVT -- Pre-procedural Evaluation and Indications -- Contraindications -- Technical Aspects of CDT -- CDT Pros and Cons -- Outcomes for CDT in DVT -- Thrombolysis in Pulmonary Embolism -- Upper Extremity DVT -- Key Points -- Further Reading -- References -- Chapter 14 Inferior Vena Cava Filters in the Management of Venous Thromboembolism -- Introduction; Evidence for IVCFs -- Complications of IVCFs -- IVCF Retrieval -- IVCFs and Anticoagulation -- Specific Indications for IVCF Placement -- IVCF for Primary PE Prophylaxis -- Conclusion -- Further Reading -- Disclosures -- References -- Section IV Special Situations -- Chapter 15 VTE in Pregnancy -- Introduction -- Incidence -- Normal Physiological Changes of Pregnancy -- Risk Factors -- Thrombophilias -- VTE Prophylaxis in Pregnancy -- Diagnosis of VTE in pregnancy -- Management -- IVC Filters -- VTE in Unusual Sites -- Thrombophilia Screening -- Massive PE/thrombolysis -- Thrombolysis for PE in Pregnancy -- Post-thrombotic Syndrome -- Follow-up -- Further Reading -- Chapter 16 Paediatric Venous Thromboembolism -- Incidence -- Paediatric Pathophysiology -- Risk Factors -- Clinical Manifestations -- Diagnosis -- Treatment -- Treatment Recommendations -- Complications -- Post-thrombotic Syndrome (PTS) -- Follow-up -- Further Reading -- Chapter 17 Cancer-associated Thrombosis -- Introduction -- Pathophysiology of Cancer‐associated Thrombosis -- The Psychological Impact of CAT -- Diagnosis of CAT -- Challenges in the Management of CAT -- Initial Treatment -- Long-term Anticoagulation -- Challenging Cases -- Use of Inferior Vena Cava Filters -- Thromboprophylaxis in Hospitalised Cancer Patients -- Thromboprophylaxis in Ambulant Cancer Patients Receiving Chemotherapy -- Conclusion -- Further Reading -- Chapter 18 Venous Thromboembolism Management in Obese Patients -- Challenges of VTE Diagnosis -- Treatment of VTE -- Drugs Where Recognised Therapeutic Drug Monitoring Overcomes the Challenges of any Changes That Obesity May Have on Drug Pharmacokinetic Profiles -- Direct Oral Anticoagulants (DOACs) -- Further Reading -- Chapter 19 Venous Thromboembolism in Intensive Care -- Introduction -- Incidence -- Diagnosis -- Thromboprophylaxis or Not?; Mechanical Thromboprophylaxis -- Treatment of Venous Thromboembolism in the Critically Ill -- Conclusion -- Further Reading -- Chapter 20 Venous Thromboembolism -- a Primary Care Perspective -- Introduction -- Prevention -- References -- Section V Unusual Site Thrombosis -- Chapter 21 Cerebral Venous Thrombosis -- Aetiology -- Pathophysiology -- Clinical Presentation -- Diagnosis -- Treatment -- Secondary Prevention in Patients at Risk -- Prognosis -- Suggested Further Reading -- Financial Disclosure -- References -- Chapter 22 Upper Extremity Thrombosis -- Overview -- Background and Classification -- Epidemiology and Risk Factors -- Prevention -- Diagnosis -- Approach to the Diagnosis of Suspected UEDVT -- Treatment -- Interventional and Endovascular Therapies -- Surgical Treatment -- Management of CVC/PICC Devices with UEDVT -- Prognosis and Complications -- References -- Chapter 23 Management of Intra-abdominal Thrombosis -- Splanchnic Vein Thrombosis -- Renal Vein Thrombosis -- Ovarian Vein Thrombosis -- Further Reading -- References -- Chapter 24 Thrombosis in the Retinal Circulation -- Introduction -- Basic Eye Anatomy -- Retinal Vein Occlusion -- Retinal Artery Occlusion -- Conclusions -- Further Reading -- Conflicts of Interest/disclosures -- References -- Section VI Long-term Sequelae of VTE -- Chapter 25 Post-thrombotic Syndrome -- Introduction -- Pathophysiology -- Signs and Symptoms -- Risk Factors for Developing PTS -- Quality of Life -- Scoring Systems -- Investigations -- Treatment -- Prevention Strategies -- Further Reading -- Chapter 26 Chronic Thromboembolic Pulmonary Hypertension -- Introduction -- Epidemiology -- Pathophysiology -- Clinical Presentation and Patient Evaluation -- Treatment -- Summary -- Further Reading -- Bibliography -- Chapter 27 Predicting Recurrent VTE -- Factors Influencing Risk of Recurrent VTE; Clinical Prediction Rules for Recurrent VTE -- Conclusions -- Further Reading -- Section VII Controversies -- Chapter 28 Cancer Screening in Unprovoked Venous Thromboembolism -- Further Reading -- Chapter 29 Sub-segmental and Incidental PE - to Treat or Not? -- Introduction -- Definitions -- Who Gets Incidental/Subsegmental PE? -- The Issue of Sub-segmental PE -- Management Approach to Incidental/Sub-segmental PE -- Conclusion -- Further Reading -- Chapter 30 Management of Distal Vein Thrombosis -- Diagnosis of Distal Deep‐vein Thrombosis -- Treatment of Isolated Distal Deep-vein Thrombosis -- References -- Section VIII Section VIII Prevention -- Chapter 31 A Summary of the Evidence for VTE Prevention, with a Focus on the Controversies -- Introduction -- Hospitalised Patients -- Further Reading -- Chapter 32 VTE Prevention: Real World Practice -- The Strategy -- Risk Assessment -- Appropriate Thromboprophylaxis (TP) -- Key Points -- Further Reading -- Chapter 33 VTE Root Cause Analysis - How To Do It -- Background -- RCA Goes Political -- the English Experience -- Aims -- References -- Index -- EULA
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