Currie, Graeme P.

ABC of COPD. - 3rd ed. - 1 online resource (132 pages) - ABC Series . - ABC Series .

Intro -- Title Page -- Copyright Page -- Contents -- Contributors -- Foreword -- Chapter 1 Definition, Epidemiology and Risk Factors -- Definition -- Epidemiology -- Prevalence -- Mortality -- Morbidity and economic impact -- Risk factors -- Smoking -- Other factors -- Air pollution -- Occupation -- α1-Antitrypsin deficiency -- Further reading -- Chapter 2 Pathology and Pathogenesis -- Introduction -- Pathology -- Pathogenesis -- Exposure to cigarette smoking, fumes, gases and particles -- Genetics -- Lung growth -- Asthma/bronchial hyperreactivity -- Chronic bronchitis -- Innate and adaptive immune inflammatory responses -- Inflammatory cells -- Inflammatory mediators -- Protease/antiprotease imbalance -- Oxidative stress -- Lung microbiome -- Pathogenesis of emphysema -- Pathophysiology -- Mucous hypersecretion and ciliary dysfunction -- Airflow limitation and hyperinflation/air trapping -- Gas exchange abnormalities -- Pulmonary hypertension -- Systemic effects -- Pathology, pathogenesis and pathophysiology of exacerbations -- Further reading -- Chapter 3 Diagnosis -- Clinical features -- Typical presenting symptoms -- Other features in the history -- Assessing the impact of COPD -- Smoking history -- Signs -- Differential diagnosis -- Investigations -- Lung function testing -- Imaging -- Other investigations -- Further reading -- Chapter 4 Spirometry -- Introduction -- What is spirometry? -- Why perform spirometry? -- Types of spirometer -- How to perform spirometry -- Spirometric indices -- Other measurements -- Forced expiratory volume in 6 seconds (FEV6) -- Slow vital capacity (SVC) (also known as relaxed VC (RVC) or VC) -- Inspired vital capacity (IVC) -- Forced midexpiratory flow (FEF25-75) -- Interpretation and classification of spirograms -- Bronchodilator reversibility testing -- Severity of airflow obstruction in COPD. Accuracy and quality of traces -- Contraindications to spirometry -- Infection control -- Further reading -- Chapter 5 Smoking Cessation -- Who smokes and effects of cigarette smoking -- The psychology of addiction -- Smoking cessation as a treatment for COPD -- Helping people to quit smoking -- Individual training -- Healthcare systems -- Smoking cessation pharmacotherapy -- Harm reduction -- Electronic cigarettes -- Further reading -- Chapter 6 Non-pharmacological Management -- Aims of management -- Smoking cessation -- Pulmonary rehabilitation -- Format -- Graded exercise -- Education -- Outcomes -- Nutrition -- Immunisation -- Influenza vaccination -- Pneumococcal vaccination -- Anxiety and depression -- Acknowledgment -- Further reading -- Chapter 7 Pharmacological Management I - Inhaled Treatment -- Physiological effects of inhaled bronchodilators -- Short-acting bronchodilators -- Long-acting bronchodilators -- Long-acting muscarinic antagonists -- Long-acting β2-agonists -- Long-acting bronchodilator combination inhalers -- Inhaled corticosteroids -- Adverse effects of inhaled corticosteroids -- Combined inhaled corticosteroid plus long-acting β2-agonist inhalers -- Triple therapy -- Practical considerations -- Summary of inhaled treatment -- References -- Chapter 8 Pharmacological Management II - Oral Treatment -- Theophylline -- Clinical use of theophylline -- Adverse effects -- Phosphodiesterase inhibitors -- Oral corticosteroids -- Prevention of corticosteroid‐associated adverse effects -- Mucolytics -- Long-term antibiotics -- β-Blockers -- Other drugs -- Acknowledgment -- References -- Chapter 9 Drug Delivery Devices -- Choosing the correct inhaler -- Errors in patient inhaler technique -- Teaching and checking patient inhaler technique -- Different types of inhalers -- Metered dose inhaler -- Soft mist inhaler -- Dry powder inhalers. Nebulisers -- Further reading -- Chapter 10 Surgical and Interventional Strategies -- Lung volume reduction strategies -- Surgical lung volume reduction approaches -- Bullectomy -- Lung volume reduction surgery -- Bronchoscopic lung volume reduction strategies -- Endobronchial valve placement -- Lung volume reduction coils -- Bronchoscopic thermal vapour ablation -- Biological lung volume reduction -- Endobronchial and extrapulmonary bypass procedures -- Lung transplantation -- Patient selection -- Timing of listing for transplantation -- Post-transplant management, complications and survival -- Summary -- Further reading -- Chapter 11 Oxygen -- Oxygen physiology -- Pulse oximetry -- Oxygen during exacerbations of COPD -- Prehospital oxygen -- Hospital oxygen -- Long-term oxygen therapy -- Ambulatory oxygen -- Short-burst oxygen -- Air travel and oxygen -- Who needs to be assessed? -- Hypoxic challenge testing -- Further reading -- Chapter 12 Exacerbations -- Definition -- Mechanism -- Clinical features -- Aetiology -- Impact -- Investigations -- Management -- Oxygen -- Bronchodilators -- Corticosteroids -- Antibiotics -- Aminophylline -- Non-invasive ventilation -- General hospital care -- Assisted hospital discharge -- Monitoring in hospital -- Care bundles -- Outpatient follow-up -- Frequent exacerbations -- Prevention of exacerbations -- Further reading -- Chapter 13 Ventilatory Support -- Why is non-invasive ventilation useful? -- Which patients with COPD should receive non-invasive ventilation? -- How non-invasive ventilation works -- Outcomes of non-invasive ventilation -- Setting -- How to use non-invasive ventilation -- Monitoring non-invasive ventilation -- Other measures -- Problems with non-invasive ventilation -- Domiciliary non-invasive ventilation -- Invasive mechanical ventilation -- Transfer to the intensive care unit. Ventilator strategies -- Further reading -- Chapter 14 Primary Care -- Quality Outcomes Framework -- Identification of patients -- Spirometry -- Follow-up of stable COPD in the community -- Organisation of care at a practice level -- National strategy -- Smoking cessation -- Referral for specialist opinion -- Management of stable disease -- Management of acute exacerbations -- Further reading -- Chapter 15 Death, Dying and End-of-Life Issues -- When do patients enter a palliative phase? -- Maintaining quality of life -- Symptom control -- Breathlessness -- Treat underlying cause, if possible and appropriate -- Non-drug approaches -- Palliative drug approaches -- Fatigue -- Depression and anxiety -- Pain -- Advance care planning -- Advance refusal of treatment -- Do not attempt cardiopulmonary resuscitation decisions -- Ways to engage patients in end-of-life discussions -- End-of-life care -- Further reading -- Chapter 16 Future Treatments -- The continuing challenge of drug development -- New bronchodilators -- More effective smoking cessation strategies -- Treating pulmonary inflammation -- Mediator antagonists -- Protease inhibitors -- New anti-inflammatory treatments -- Lung repair -- Route of delivery -- Targeted lung denervation -- Further reading -- Index -- EULA.

9781119212812


Lungs--Diseases, Obstructive.


Electronic books.

RC776.O3.A23 2017

616.2/4