Vertigo : Five Physician Scientists and the Quest for a Cure.
- 1st ed.
- 1 online resource (257 pages)
Cover -- Vertigo -- Copyright -- Contents -- Preface -- Acknowledgments -- 1. Introduction -- The Inner Ear -- Dizziness, Vertigo, and the Inner Ear -- What Is Benign Paroxysmal Positional Vertigo? -- Who Discovered the Cure? -- Section 1 Prosper Ménière (1799-1862) -- 2. Ménière Recognizes That Vertigo Can Originate from the Inner Ear -- What Was Known About the Inner Ear in the Mid-19th Century? -- First Hint That the Semicircular Canals May Be Related to Balance -- Ménière Presents His Findings in 1861 -- The First Recorded Case of Ménière's Disease? -- More Evidence That Vertigo Can Originate from the Inner Ear -- Inconsistencies in Ménière's Description of the Young Girl with Vertigo -- Treatments for Vertigo in the Mid-19th Century -- Ménière's Comments Trigger Heated Debate -- 3. Ménière, a Man of Many Interests -- Ménière's Academic Career -- Ménière Balances Academic, Patient, and Family Activities -- Ménière's Everyday Life -- Ménière's Role in French Society -- Section 2 Josef Breuer (1842-1925) -- 4. Breuer Discovers How the Balance Portion of the Inner Ear Works -- Eye Movements and the Semicircular Canals -- The Gravity-Sensing Otolith Organs -- Evolutionary Development of the Inner Ear -- Mach and His Psychophysical Experiments -- Breuer and Mach Work Together to Defend Their Theory -- Crum-Brown, the Model Maker -- Who Contributed Most to Our Current Understanding of the Vestibular System? -- 5. Breuer, the Renaissance Man -- Upbringing and Formative Years -- Breuer's Medical Training -- Breuer Chooses Private Practice over Academic Medicine -- Breuer, the Family Doctor -- 6. Breuer's Experiments on the Semicircular Canals and Otolith Organs -- Studies on the Semicircular Canals -- Ewald's Laws -- The Breuer-Von Cyon Feud -- Studies on the Otolith Organs -- Overview of the Inner Ear Sensory Receptors. 7. Breuer's Contributions to Psychiatry and Philosophy -- Freud's Early Work in Neuroanatomy -- Anna O. and the Beginnings of Psychoanalysis -- Breuer and Freud and Studies on Hysteria -- The Friendship Between Breuer and Freud Dissolves -- Breuer's Philosophical Beliefs -- The Final Years -- Section 3 Robert Bárány (1876-1936) -- 8. Politzer's Otology Clinic and the Discovery of the Caloric Test -- Politzer Maneuver -- Teaching in Politzer's Clinic -- Robert Bárány Joins Politzer's Clinic -- Bárány Discovers the Caloric Test -- 9. Bárány's Formative Years and the Conflict in Politzer's Clinic -- Bárány's Medical Training -- Source of Conflict in Politzer's Clinic -- Accusations Against Bárány -- 10. The War Years and Bárány's Decision to Leave Vienna -- Bárány Receives the 1914 Nobel Prize in Medicine -- Formal Charges Against Bárány -- Nobel Committee Response -- Questions Regarding Bárány's Caloric Theory -- 11. Bárány's Test Battery and the First Description of Benign Paroxysmal Positional Vertigo -- Romberg Test -- Past-Pointing Test -- Bárány's Syndrome -- First Description of Benign Paroxysmal Positional Vertigo -- 12. Bárány's Life in Uppsala and His Work with Lorente de Nó -- The Brain and the Neuronal Theory -- Lorente de Nó and Bárány in Spain -- Lorente de Nó Works on Central Vestibular Pathways with Bárány -- Bárány's Final Years -- Section 4 Charles Hallpike (1900-1979) -- 13. Hallpike and the Pathology of Ménière's Disease -- Toynbee and Early Efforts to Study Pathology of the Inner Ear -- Wittmaack and His New Technique for Preparing Temporal Bones -- Worldwide Interest in Wittmaack's Technique -- Hallpike and Cairns Report on the Pathology of Ménière's Syndrome -- Possible Causes of Ménière's Syndrome -- Yamakawa Also Describes the Pathology of Ménière's Syndrome -- 14. Hallpike's Formative Years -- The Indian Connection. Early Education and Dealing with Legg-Perthes Disease -- Medical Training -- Personal Life -- Hallpike the Inventor -- Appointment at Queen Square -- Hallpike's Colleagues at Queen Square -- War Years -- Queen Square Neurotology Clinic -- 15. Hallpike's Caloric Test -- Preparing the Water -- Hallpike's Caloric Chart -- The Meaning of a Directional Preponderance -- Importance of Tonic Signals Originating from the Inner Ears -- Controversy Regarding the Effect of Cortical Lesions -- 16. Hallpike Defines the Syndrome of Benign Paroxysmal Positional Vertigo -- Clinical Features of BPPV -- Confusion Regarding the Direction of the Positional Nystagmus -- Strong Evidence for an Inner Ear Origin -- Pathology of BPPV -- Final Years -- Section 5 Harold Schuknecht (1917-1996) -- 17. Schuknecht and His Breakthrough on Benign Paroxysmal Positional Vertigo -- John Lindsay and the University of Chicago Otology Clinic -- Schuknecht Begins His Residency at the University of Chicago -- Schuknecht's Formative Years -- Schuknecht Becomes Interested in BPPV -- Search for the Cause of BPPV -- Schuknecht Suggests a New Mechanism for BPPV -- 18. Schuknecht's Temporal Bone Bank in Boston -- More Temporal Bone Specimens from Patients with Benign Paroxysmal Positional Vertigo -- The Cupulolithiasis Theory -- Schuknecht Was Not the First to Propose the Cupulolithiasis Theory -- A Key Question: Which Way Does the Cupula Deviate? -- How to Explain the Stereotypical Nystagmus -- Problems with the Cupulolithiais Theory -- 19. Schuknecht's Crusade Against Myths in Otology -- Surgical Treatments of Ménière's Disease -- Viral Neurolabyrinthitis -- Questionable Surgical Procedures -- The Final Years -- Section 6 The Pieces of the Puzzle Come Together -- 20. Semont and Epley Maneuvers -- Treatments Based on the Cupulolithiasis Theory -- Semont's Maneuver. Cupulolithiasis Versus Canalithiasis -- Epley's Maneuver -- Visualization of the Free-Floating Otolith Debris -- 21. Evolution of Treatment Maneuvers for Benign Paroxysmal Positional Vertigo -- Epley's Maneuver -- Semont's Maneuver -- Features Shared by the Maneuvers -- Variations on the Theme -- Horizontal Canal BPPV -- 22. Conclusions -- Glossary -- Index.
Vertigo: Five Physician Scientists and the Quest for a Cure follows this centuries long trek. The book follows the key discoveries made by Prosper Meniere (1799-1862) who first recognized that vertigo could originate from the inner ear, Josef Breuer (1842-1925) who conducted groundbreaking research on the inner ear during his evenings at home after he spent his days working in a busy private medical practice, Robert Barany (1876-1936) who received the Nobel Prize for his early work on the inner ear, Charles Hallpike (1900-1979) who showed that BPPV originates from the inner ear, and Harold Schuknecht (1917-1996) who provided key observations on the mechanism of BPPV.