TY  - BOOK
AU  - Best,Charles Herbert
TI  - Selected Papers of Charles H. Best
T2  - Heritage Series
SN  - 9781442656918
AV  - R117.S454 1963eb 
PY  - 2014///
CY  - Toronto
PB  - University of Toronto Press
KW  - Best, Charles Herbert,-1899-1978
KW  - Medicine
KW  - Electronic books
N1  - Cover -- Contents -- FOREWORD -- PREFACE -- INTRODUCTION -- 1. A Canadian trail of medical research -- PART I: INSULIN AND GLUCAGON -- 2. The internal secretion of the pancreas (selected pages of the original manuscript) -- 3. The internal secretion of the pancreas -- 4. The internal secretion of the pancreas -- 5. Pancreatic extracts -- 6. Preliminary studies on the physiological effects of insulin: The preparation of the earlier pancreatic extracts containing insulin -- 7. Pancreatic extracts in the treatment of diabetes mellitus: A Preliminary Report -- 8. The effects of insulin on experimental hyperglycaemia in rabbits -- 9. The preparation of insulin -- 10. The effect of insulin on the dextrose consumption of perfused skeletal muscle -- 11. The fate of the sugar disappearing under the action of insulin -- 12. Oxidation and storage of glucose under the action of insulin -- 13. Insulin in tissues other than the pancreas -- 14. Diet and the insulin content of pancreas -- 15. Insulin extractable from the pancreas and islet cell histology -- 16. Extractable insulin of the pancreas and effectiveness of oral hypoglycaemic sulphonylureas in the treatment of diabetes in man-a comparison -- 17. A study of the prevalence of diabetes in an Ontario community -- 18. The prevention of diabetes -- 19. The protein anabolic effect of testosterone propionate and its relationship to insulin -- 20. The pathologic effects of large amounts of glucagon -- 21. Glucagon and metaglucagon diabetes in rabbits -- 22. Effect of insulin and glucagon on tumour growth -- 23. Effect of prolonged administration of tolbutamide in depancreatized dogs -- 24. A clinical assessment of foetal calf insulin -- 25. The late John James Rickard Macleod (Obituary). -- 26. Frederick Grant Banting (Obituary). -- 27. Reminiscences of the researches which led to the discovery of insulin; 28. The Banting Memorial Lecture: Insulin and diabetes in retrospect and in prospect. -- 29. The Banting Memorial Lecture: Insulin. -- 30. Diabetes since 1920. -- 31. Insulin and glucagon: A review -- 32. The future in the field of diabetes. -- PART II: CHOLINE AND LIPOTROPIC PHENOMENA -- 33. A brief history of the discovery of the lipotropic factors. -- 34. The effect of lecithine on fat deposition in the liver of the normal rat -- 35. The effects of the components of lecithine upon deposition of fat in the liver -- 36. Choline and the dietary production of fatty livers -- 37. Distribution of choline -- 38. The effects of cholesterol and choline on liver fat -- 39. The effect of anterior pituitary extracts on the liver fat of various animals -- 40. A study of the source of liver fat using deuterium as an indicator -- 41. The lipotropic action of methionine -- 42. The mode of action of lipotropic agents -- 43. Hypertension of renal origin in rats following less than one week of choline deficiency in early life -- 44. Liver damage produced by feeding alcohol or sugar and its prevention by choline -- 45. Effects of dietary protein, lipotropic factors and re-alimentation on total hepatic lipids and their distribution -- 46. Lipotropic dose-response studies in rats: Comparisons of choline, betaine and methionine -- 47. Kwashiorkor type of fatty liver in primates -- 48. The Croonian Lecture: The lipotropic agents in the protection of the liver, kidney, heart and other organs of experimental animals. -- PART III: OTHER PHYSIOLOGICAL STUDIES -- 49. Observations on Olympic athletes -- 50. The nature of the vaso-dilator constituents of certain tissue extracts -- 51. The disappearance of histamine from autolysing lung tissue -- 52. The inactivation of histamine -- 53. Preparation of heparin and its use in the first clinical cases; 54. Heparin and the thrombosis of veins following injury -- 55. Heparin and the formation of white thrombi -- 56. Heparin and coronary thrombosis in experimental animals -- 57. Experimental exchange transfusion using purified heparin -- 58. The Canadian project for the preparation of dried human serum for military use -- PART IV: GENERAL PAPERS -- 59. A short essay on the Division of Naval Medical Research in the Royal Canadian Navy. -- 60. The Organization of Physiology. -- 61. Convocation Address at the University of Maine, August 12, 1955. -- PART V: EPILOGUE -- BIBLIOGRAPHY
N2  - This volume records the achievements of forty years of medical research, giving direct and easy access to over sixty of Dr. Best's original important research papers in the fields particularly of insulin, heparin, and choline
UR  - https://ebookcentral.proquest.com/lib/orpp/detail.action?docID=4669417
ER  -