Love, J. Christopher.
Micro- and Nanosystems for Biotechnology.
- 1st ed.
- 1 online resource (374 pages)
- Advanced Biotechnology Series .
- Advanced Biotechnology Series .
Intro -- Related Titles -- Title Page -- Copyright -- Table of Contents -- List of Contributors -- About the Series Editors -- Preface -- part I: Microsystems for Single-Cell Analysis -- Chapter 1: Types of Clinical Samples and Cellular Enrichment Strategies -- 1.1 Introduction -- 1.2 Types of Clinical Samples -- 1.3 Sample Processing and Conventional Methods of Cell Enrichment -- 1.4 Microscale/Nanoscale Devices for Cellular Enrichment -- 1.5 Conclusion -- References -- Chapter 2: Genome-Wide Analysis of Single Cells and the Role of Microfluidics -- 2.1 Motivation for Single-Cell Analysis of Genomes and Transcriptomes -- 2.2 Single-Cell Genomics -- 2.3 Single-Cell Transcriptomics -- 2.4 The Future of Genome-Wide Single-Cell Analysis with Microfluidics -- References -- Chapter 3: Cellular Immunophenotyping: Industrial Technologies and Emerging Tools -- 3.1 Cellular Immune Status and Immunophenotyping -- 3.2 Surface Marker Phenotyping -- 3.3 Functional Phenotyping -- 3.4 Conclusion -- References -- Chapter 4: Microsystem Assays for Studying the Interactions between Single Cells -- 4.1 Introduction -- 4.2 Advantages of Single-Cell Analysis over Conventional Assay Systems -- 4.3 Analysis of Cell-Cell Communication between Pairs of Single Cells -- 4.4 Conclusions -- Acknowledgments -- References -- Chapter 5: Modeling Microvascular Disease -- 5.1 Introduction -- 5.2 Microvascular Disease -- 5.3 Macromodeling -- 5.4 Micromodeling -- 5.5 Summary -- References -- Part II: Tiny Technologies for Modulating Biological Systems -- Chapter 6: Nanotechnologies for the Bioelectronic Interface -- 6.1 Introduction -- 6.2 Modeling the Bioelectronic Interface -- 6.3 Experimental Approaches for Extra-Cellular Coupling -- 6.4 State-of-the-Art Extra-Cellular Nanoscale Interfaces -- 6.5 Experimental Approaches for Intra-Cellular Coupling. 6.6 State-of-the-Art Intra-Cellular Nanoscale Interfaces -- 6.7 Experimental Approaches for In-Cell Coupling -- 6.8 Outlook -- References -- Chapter 7: Intracellular Delivery of Biomolecules by Mechanical Deformation -- 7.1 Introduction -- 7.2 Delivery Concept -- 7.3 Cytosolic Delivery by Diffusion -- 7.4 Applicability across Cell Types and Delivery Materials -- 7.5 Summary -- 7.6 Appendix -- Acknowledgments -- Conflict of Interest -- References -- Chapter 8: Microfluidics for Studying Pharmacodynamics of Antibiotics -- 8.1 Background on Antibiotic Resistance -- 8.2 Methods for Antibiotic Susceptibility Testing (AST) -- 8.3 Applying Pharmacokinetics/Pharmacodynamics to AST -- 8.4 Application of Microfluidic-Based Approach for PK/PD Modeling -- 8.5 Summary and Future Outlook -- Acknowledgments -- References -- Chapter 9: Microsystems Models of Pathophysiology -- 9.1 Vascular and Hematologic Pathologies -- 9.2 Organ-Specific Pathologies -- 9.3 Cancer -- 9.4 Summary -- References -- Chapter 10: Microfluidic Systems for Whole-Animal Screening with C. elegans -- 10.1 Importance -- 10.2 Introduction -- 10.3 A Versatile Animal Model: Caenorhabditis elegans (C. elegans) -- 10.4 Microfluidics -- 10.5 Microfluidics for C. elegans Biology -- 10.6 Conclusions and Future Directions -- Author Contributions -- References -- Index -- End User License Agreement.
9783527801329
Biotechnology.
Electronic books.
TP248.2 -- .M53 2016eb