Randomization in Clinical Trials : Theory and Practice. - Rosenberger, William F.; Lachin, John M. (Newark : John Wiley & Sons, Incorporated, 2015)
10.2.2 Roots in sequential stopping problems -- 10.2.3 Roots in randomization -- 10.3 Optimal Allocation -- 10.4 Response-Adaptive Randomization to Target R* -- 10.4.1 Sequential maximum likelihood procedure -- 10.4.2 Doubly adaptive biased coin design -- 10.4.3 Example -- 10.4.4 Efficient randomized-adaptive design -- 10.5 Urn Models -- 10.5.1 The generalized Friedman's urn model -- 10.5.2 The randomized play-the-winner rule -- 10.5.3 Designs to target any allocation -- 10.5.4 Ternary urn models -- 10.5.5 Klein urn -- 10.6 Treatment Effect Mappings -- 10.7 Covariate-Adjusted Response-Adaptive Randomization -- 10.8 Problems -- 10.9 References -- 10.10 Appendix -- Chapter 11 Inference for Response-Adaptive Randomization -- 11.1 Introduction -- 11.2 Population-Based Inference -- 11.2.1 The likelihood -- 11.2.2 Sufficiency -- 11.2.3 Bias of the maximum likelihood estimators -- 11.2.4 Confidence interval procedures -- 11.3 Power -- 11.3.1 The relationship between power and the variability of the design -- 11.3.2 Asymptotically best procedures -- 11.3.3 Response-adaptive randomization and sequential monitoring -- 11.4 Randomization-Based Inference -- 11.5 Problems -- 11.6 References -- Chapter 12 Response-Adaptive Randomization in Practice -- 12.1 Basic Assumptions -- 12.2 Bias, Masking, and Consent -- 12.3 Logistical Issues -- 12.4 Selection of A Procedure -- 12.5 Benefits of Response-Adaptive Randomization -- 12.6 Some Examples -- 12.6.1 The extracorporeal membrane oxygenation trial -- 12.6.2 The fluoxetine trial -- 12.7 Conclusions -- 12.8 Problems -- 12.9 References -- Author Index -- Subject Index -- Wiley Series in Probability and Statistics -- EULA.
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Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.
Keywords: Clinical trials; Electronic books