The AIDS Research Program of the National Institutes of Health.

The AIDS Research Program of the National Institutes of Health -- Copyright -- Preface -- Contents -- Summary -- AIDS: THE RESEARCH CHALLENGE -- MANAGING THE NIH AIDS RESEARCH PROGRAM -- Strengthening Planning and Evaluation -- Planning -- Evaluation -- Strengthening External Advisory Processes -- Strengthening Staff Support -- Strengthening Executive Authority and Flexibility -- ELEMENTS OF THE NIH AIDS RESEARCH PROGRAM -- Basic Research -- Vaccines -- Epidemiology -- Behavioral Research -- Nursing Research -- Preclinical Drug Development -- Clinical Trials -- Mission -- Efficiency Within the ACTG -- Accrual -- Coordination -- Information Dissemination -- Research Resources -- Training -- Animal Models -- Facilities -- Communication of Research Results -- SUPPORTING THE NIH AIDS RESEARCH PROGRAM -- Funding of AIDS Research -- Grants Policy and Administration -- Administrative Support -- Staffing -- Facilities -- 1 AIDS: the Research Challenge -- UNIQUENESS OF THE EPIDEMIC -- NIH'S RESPONSE TO THE EMERGING EPIDEMIC -- DEMOGRAPHICS AND PROJECTIONS OF THE EPIDEMIC -- HEALTH CARE FINANCING -- REFERENCES -- 2 Managing the NIH AIDS Research Program -- ORGANIZATIONAL STRUCTURE -- Associate Director for AIDS Research -- AIDS Program Advisory Committee -- NIH AIDS Executive Committee -- Office of AIDS Research -- STRENGTHENING MANAGEMENT OF THE NIH AIDS RESEARCH PROGRAM -- Strengthening Planning and Evaluation -- Planning -- Evaluation -- Strengthening External Advisory Processes -- Strengthening Staff Support -- Strengthening Executive Authority and Flexibility -- REFERENCES -- 3 Elements of the NIH AIDS Research Program -- BASIC RESEARCH -- VACCINE RESEARCH AND DEVELOPMENT -- NIH Vaccine Research Program -- National Institute of Allergy and Infectious Diseases -- National Cancer Institute -- The Role and Mission of NIH -- EPIDEMIOLOGICAL RESEARCH.

National Institute of Allergy and Infectious Diseases -- National Heart, Lung, and Blood Institute -- National Cancer Institute -- National Institute of Child Health and Human Development -- Fogarty International Center -- Other NIH Epidemiological Studies -- Results -- NIH's Role in Epidemiology Research -- Establishing Epidemiological Research Priorities -- Coordination of Studies -- BEHAVIORAL RESEARCH -- NURSING RESEARCH -- PRECLINICAL DRUG DISCOVERY AND DEVELOPMENT -- National Cancer Institute -- National Institute of Allergy and Infectious Diseases -- National Institute of General Medical Sciences -- NIH's Role in Preclinical Drug Development -- Anti-HIV Agents -- Agents for Opportunistic Infections -- CLINICAL TRIALS -- Mission of the AIDS Clinical Trials Group -- Efficiency Within the ACTG -- Accrual -- Coordination -- Information Dissemination -- RESEARCH RESOURCES -- Training -- Animal Models -- Facilities and Equipment -- COMMUNICATION OF RESEARCH RESULTS -- REFERENCES -- 4 Supporting the NIH AIDS Research Program -- FUNDING AIDS RESEARCH -- History of AIDS Funding -- NIH and Its Institutes -- Research Support Mechanisms -- Categories of Research -- Adequacy -- Impact on Non-AIDS Research -- Spillover Effects of AIDS Research on Non-AIDS Efforts -- GRANTS POLICY AND ADMINISTRATION -- Problems in Responding to the AIDS Epidemic -- The Current System -- Division of Research Grants Capacity -- Quality of AIDS Research Applications -- Success of AIDS Research Applications -- Conclusion -- ADMINISTRATIVE SUPPORT -- Staffing -- Traditional Personnel Problems -- Constraints of Federal Personnel Ceilings -- Facilities -- Conclusion -- REFERENCES -- Appendix A Study Issues -- Appendix B Persons Who Were Interviewed by Committee or Staff or Who Provided Written Materials -- Appendix C National Institutes of Health Aids Program Advisory Committee.

Appendix D Abbreviations and Acronyms.

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