Bacillus : Cellular and Molecular Biology.

Intro -- Contents -- Preface -- Useful links -- Current Books of Interest -- 1 Replication of the Bacillus subtilis Chromosome -- Introduction -- The basics of DNA replication in Escherichia coli -- Chromosomal DNA replication in Bacillus subtilis -- Conclusions and future perspectives -- 2 Dynamics of DNA Double-strand Break Repair in Bacillus subtilis -- Introduction -- Specific DNA repair pathways -- RecA forms filamentous structures 'threads' in vivo -- RecA mediators and modulators -- Conclusions and perspectives -- 3 Chromosome Arrangement and Segregation -- Chromosome compaction -- Chromosome arrangement and sister chromosome segregation -- Replication -- Topoisomerases -- Proteins mediating homologous recombination are involved in chromosome segregation -- SMC proteins and the SMC/ScpAB complex organize the arrangement of duplicated chromosome arms -- Soj and Spo0J protein -- Two DNA translocases couple late stages of segregation with cell division -- Coordination of chromosome segregation and cell division -- The segregation motor -- Chromosome segregation during sporulation -- Conclusions -- 4 Cell Division -- Introduction -- Anatomy of Bacillus subtilis and Escherichia coli envelopes: implications for cytokinesis -- Overview of cytokinesis -- Bacillus subtilis division proteins -- FtsZ and the Z ring -- FtsZ binding proteins - early divisome components -- Late divisome components and the synthesis of septal peptidoglycan -- Proteins that coordinate cytokinesis with chromosome segregation -- Assembly of the divisome -- The final steps of septum formation: divisome constriction, membrane fission and cell separation -- Regulation of septum formation -- Other regulators of Bacillus subtilis cell division -- Asymmetrical division during sporulation -- The mechanism of the switch of division site.

Why does only one of the bipolar Z rings become a septum? -- Perspectives -- 5 The Organization of Transcription and Translation -- Background -- Transcription organization within the cell -- Translation organization within the cell -- Conclusions -- 6 RNA-mediated Regulation in Bacillus subtilis -- Introduction -- Biological roles of ribonucleotides -- Noncoding RNAs and ribonucleoprotein complexes -- Regulatory RNAs in Bacillus subtilis -- Cis-acting regulatory RNAs -- Trans-acting regulatory RNAs -- Concluding comments -- 7 General and Regulatory Proteolysis in Bacillus subtilis -- Introduction -- Proteases and peptidases of Bacillus subtilis -- Proteolysis, protein quality control and regulation in the cytosol of Bacillus subtilis -- Proteolysis, regulation and quality control in the membrane of Bacillus subtilis -- Conclusion and outlook -- 8 The Actin-like MreB 'Cytoskeleton' -- Introduction -- The eukaryotic actin cytoskeleton -- Actin-binding proteins: regulators of the actin cytoskeleton -- The actin 'cytoskeleton' of Bacillus subtilis -- MreB and chromosomal DNA segregation -- MreB and genetic competence -- MreB and organization of the cell membrane -- MreB and organization of viral DNA replication -- Other functions of the MreB cytoskeleton in bacteria -- MreB-associated proteins: effectors and regulators of the actin-like cytoskeleton -- Conclusions -- 9 Ins and Outs of the Bacillus subtilis Membrane Proteome -- Introduction and scope of this review -- The membrane of Bacillus subtilis -- Membrane protein biogenesis -- Membrane protein localization -- Membrane protein degradation -- How many membrane proteins in Bacillus subtilis? -- Conclusions -- 10 The Cell Wall of Bacillus subtilis -- Introduction -- Cell wall structure and composition -- Cell wall synthesis -- Penicillin-binding proteins in Bacillus subtilis: activity and expression.

Cell wall turnover -- Organization of cell wall synthesis in Bacillus subtilis -- Life without a wall - conundrums and open questions -- Concluding remarks -- 11 Genomics and Cellular Biology of Endospore Formation -- Introduction -- Making a spore -- Regulation of sporulation gene expression -- The sporulation regulons -- Cellular biology of sporulation -- Future perspectives -- 12 Multicellularity and Social Behaviour in Bacillus subtilis -- Introduction -- Multicellularity in Bacillus subtilis: formation of biofilms, pellicles and fruiting bodies -- Swarming motility -- Cannibalistic behaviour during sporulation -- Extracellular DNA production -- Concluding remarks: Bacillus subtilis as a multicellular microorganism -- 13 Competence and Transformation -- Introduction -- Development of competence for transformation -- Molecular mechanism of transformation -- Conclusions -- 14 Swimming, Swarming and Sliding Motility in Bacillus subtilis -- Flagellar structure and assembly -- Swimming motility -- Swarming motility -- Sliding motility -- 15 Nucleotide Second Messengers: (p)ppGpp and Cyclic Dinucleotides -- Introduction -- Alarmones -- Physiological roles of (p)ppGpp and its associated effectors -- Other nucleotide alarmones -- Cyclic nucleotides -- Conclusion -- Index.

The third edition of this authoritative reference work is indispensable to Bacillus scientists and invaluable for anyone involved in bacterial cell biology. Revised, updated and expanded with two new chapters on motility and nucleotide regulation, the new edition provides up-to-date reviews on current Bacillus research. Subjects covered include chromosome replication, DNA repair, chromosome segregation, cell division, transcription and translation, RNA-mediated regulation, general and regulatory proteolysis, the MreB cytoskeleton, membrane proteins, the cell wall, sporulation, biofilms, multicellularity and social behaviour, competence and transformation, motility and nucleotide regulation. An essential book for anyone involved in Bacillus and an invaluable reference work for those working in fields as diverse as medicine, biotechnology, agriculture, food and industry. A recommended acquisition for all microbiology laboratories.

Description based on publisher supplied metadata and other sources.

Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.