Avian Virology : Current Research and Future Trends.

Intro -- Contents -- Current Books of Interest -- Preface -- 1. Avian Influenza Virus -- Introduction -- Historical perspective -- Infectious agent -- Natural hosts and host range -- Clinical features and pathogenesis: LPAIV and HPAIV in poultry -- Adaptive immune responses -- Immune evasion strategies of influenza A viruses -- Virus evolution and reverse genetics -- Diagnosis -- Vaccination -- Public health significance -- Perspective -- 2. Newcastle Disease Virus -- History -- Geographic distribution -- Natural and experimental host range -- Infectious agent -- Genome organization, transcription and RNA replication -- Viral proteins -- Overview of NDV replication -- Genetics -- Reverse genetics -- NDV as a vaccine vector -- NDV as an oncolytic agent -- Antigenic and genetic variations among NDV isolates -- NDV infections in wild birds -- Pigeon paramyxovirus type 1 -- Molecular basis of NDV virulence -- Emergence of virulent NDV -- Transmission and spread -- Clinical signs -- Pathology -- Diagnosis -- Virus characterization -- Immune response to NDV -- Control of ND -- Vaccination -- Future perspectives -- 3. Avian Paramyxoviruses Other Than Newcastle Disease Virus -- Introduction -- Classification -- Antigenic relationships -- Geographic distribution -- Host range -- Disease associated with avian paramyxoviruses -- Isolation and identification of APMVs -- General virion structure and replication strategy -- Viral proteins -- APMVs from genus Orthoavulavirus -- APMVs from genus Metaavulavirus -- APMVs from genus Paraavulavirus -- Reverse genetics -- Role of F protein cleavage site sequence on APMV pathogenesis -- Evaluation as vaccine vectors -- Perspectives and future directions in research -- 4. Avian Metapneumoviruses -- Introduction and history -- Infectious agent -- Viral replication -- Reverse genetics -- Pathogenesis -- Clinical features.

Immune responses -- Epizootiology -- Diagnosis -- Prevention and control -- Perspectives -- 5. Infectious Bronchitis Virus -- History -- Nomenclature -- Morphology -- Propagation -- Genome structure and organization -- Structural proteins: structure and function -- Non-structural and accessory proteins: structure and function -- Stages of viral replication -- Effects on the host cell -- Evolution -- Genetics and reverse genetics -- Pathogenesis and clinical features -- Immune responses -- Epizootiology -- Diagnosis -- Prevention and control -- Perspectives -- 6. Avian Reovirus -- Introduction and history -- Infectious agent -- Primary cell cultures -- Continuous cell lines -- Genetics and reverse genetics -- Pathogenesis -- Clinical features -- Immune responses -- Epizootiology -- Diagnosis -- Prevention and control -- Perspectives -- 7. Infectious Bursal Disease Virus -- Introduction -- Virus characteristics -- IBDV and host interaction -- Control of IBD by vaccination -- Future perspective -- 8. Avian Leukosis Virus -- Introduction and history -- Infectious agent -- Genome structure and organization -- Viral proteins -- Virus replication -- Avian leukosis virus envelope subgroups -- Exogenous and endogenous avian leukosis viruses -- Transmission and epizootiology -- Flock infection -- Spread of infection -- Clinical features and pathogenesis -- Immune responses -- Diagnosis -- Intervention strategies -- Prevention and control procedures -- Perspectives -- 9. Chicken Infectious Anaemia Virus -- Introduction and history -- Infectious agent -- Genetics -- Pathogenesis -- Clinical features and pathology -- Immune responses -- Immunosuppression -- Epizootiology -- Diagnosis -- Economic importance -- Prevention and control -- Perspectives -- 10. Avian Adenoviruses -- Introduction and history -- Infectious agent -- Viral replication.

Effects on the host cell, signalling pathways and apoptosis -- Genome structure and organization -- Phylogeny and evolutionary relationships -- Pathogenesis -- Virulence -- Clinical features -- Immune response -- Epizootiology -- Diagnosis -- Prevention and control -- Aviadenovirus as vaccine and gene delivery vector -- Perspectives -- 11. Infectious Laryngotracheitis Virus -- Introduction -- Molecular biology and viral genetics -- Pathogenesis and immunity -- Clinical features, diagnosis and epizootiology -- Vaccines -- 12. Marek's Disease Virus -- Introduction and history -- Infectious agent -- MDV genome replication -- Molecular oncogenesis -- Genome manipulation -- Life cycle -- Pathogenesis -- Diagnosis -- MDV vaccines -- Perspectives -- 13. Avian Pox Viruses -- Introduction -- Etiological agent -- Immune responses -- Immunoblotting -- Genome -- Genomic differences among avian pox viruses -- Virus replication -- Virus survival strategies -- Host-related functions -- Mixed infections -- Role of REV in the fowlpox virus genome -- Prevention -- Perspectives -- 14. Avian Immune Responses to Virus Infection -- Introduction -- Innate host responses -- The adaptive immune system -- Future prospects -- Index.

This comprehensive book provides a timely update on all of the most important avian viruses: avian influenza virus, infectious bronchitis virus, Newcastle disease virus, infectious bursal disease virus, chicken anemia virus, infectious laryngotracheitis virus, avian adenovirus, Marek's disease virus, avian reovirus, avian pox virus, avian leukosis virus, avian metapneumovirus, and avian paramyxoviruses. The chapters are written by internationally recognized experts from all over the world who have made seminal contributions to their respective field of avian virus research. Each chapter covers the current knowledge on the history, genome organization, viral proteins, genetics, epizootiology, pathogenesis, immunity, diagnosis, prevention and control, and future challenges of these viruses. The book closes with a fascinating chapter that reviews the recent advances on avian immune responses to virus infection. This book is an invaluable reference source of timely information for students, virologists, immunologists, veterinarians, and scientists working on avian diseases. It is also highly recommended for all veterinary school and university libraries.

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Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.