Atlas of Cardiac Innervation.

Intro -- Preface -- Contents -- Contributors -- 1: Anatomy and Molecular Basis of Autonomic Innervation of the Heart -- Introduction -- Distribution of Autonomous Nervous System in the Heart -- Sympathetic Neuronal Synapse in the Heart -- Signal Transduction of the Postsynaptic Cardiac Adrenergic Receptors -- Heterogeneity of Innervation in the Normal Heart -- Reinnervation in the Transplanted Heart -- Molecular Regulation of Cardiac Nerve Development -- Sympathetic Dysfunction in Cardiac Diseases -- Heart Failure -- Cardiomyopathy -- Sudden Cardiac Death -- References -- 2: Neural Control of Cardiac Function in Health and Disease -- Introduction -- Cardiac Motor Neurons: Efferent Control of Cardiac Function -- Cardiac Sensory Neurons -- ICNS: Organ-Level Control -- Cardiac ANS in Disease -- Cardiac ANS Neuromodulation -- References -- 3: Chemistry and Biology of Radiotracers Designed to Target Changes in the Myocardial Sympathetic and Parasympathetic Nervous Systems as a Function of Disease or Treatment -- References -- 4: Neuronal Imaging in Heart Failure -- Introduction -- Physiology and Pharmacokinetics -- MIBG Imaging and the Sympathetic Nervous System in Heart Failure -- Planar MIBG Imaging for Prognostic Assessment -- MIBG SPECT for Arrhythmic Risk Assessment -- Risk Assessment with MIBG Imaging in Conjunction with Other Clinical Measurements and Multivariate Models -- Considerations for Clinical Use of MIBG Imaging in HF Patients -- References -- 5: PET Imaging and Quantitation of Cardiac Innervation -- Cardiac Autonomic Innervation -- PET Radiotracers for Evaluation of Cardiac Autonomic Innervation -- Principles of PET Image Acquisition, Quantitation, and Interpretation -- Quantitation of Myocardial HED Uptake -- Myocardial HED Radiotracer Time-Activity Curve -- HED Retention Index -- Standard Uptake Value.

Polar Map Representation of Tracer Uptake -- Kinetic Modeling of Tracer Uptake and Disposition -- Graphic Method of β-Adrenergic Receptor Density Estimation -- References -- 6: Neuronal Imaging and Reverse Remodeling -- Introduction -- What Is Reverse Remodeling, and Why Is It Important? -- Effects of LVADs on Sympathetic Neuronal Imaging -- Effects of CRT on Sympathetic Neuronal Imaging -- Predicting CRT Response by Using Sympathetic Neuronal Imaging -- Effects of Medical Therapy on Sympathetic Neuronal Imaging -- Predicting Drug Response by Using Sympathetic Neuronal Imaging -- Prognostic Value of Sympathetic Reverse Remodeling -- Positron Emission Tomography to Assess Reverse Remodeling -- References -- 7: Neuronal Imaging, Ventricular Arrhythmias, and Device Therapy in Heart Failure -- References -- 8: Cardiac Sympathetic Innervation and Ablation of Ventricular Tachycardia -- References -- 9: Dysautonomia: From the Brain Disorders to Neuropathies and Including Diabetes -- Introduction -- Neurodegenerative Diseases -- Cardiovascular Autonomic Diabetic Neuropathy -- 123I-MIBG Imaging in CADN -- 123I-MIBG Imaging in the Assessment of Prognosis -- 123I-MIBG Imaging in the Assessment of Treatment -- Other Neuropathies -- Conclusions -- References -- 10: Cardiac Transplantation: Denervation, Reinnervation, and Myocardial Blood Flow -- Cardiac Denervation during Heart Transplantation -- Effect of Reinnervation on Outcome -- References -- Index.

Description based on publisher supplied metadata and other sources.

Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.