Possible Long-Term Health Effects of Short-Term Exposure to Chemical Agents : (Record no. 85267)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 07964nam a22004573i 4500 |
| 001 - CONTROL NUMBER | |
| control field | EBC3377964 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MiAaPQ |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20240729125320.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS | |
| fixed length control field | m o d | |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr cnu|||||||| |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 240724s1982 xx o ||||0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9780309593786 |
| Qualifying information | (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Canceled/invalid ISBN | 9780309077590 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (MiAaPQ)EBC3377964 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (Au-PeEL)EBL3377964 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (CaPaEBR)ebr10085524 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (OCoLC)923274692 |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | MiAaPQ |
| Language of cataloging | eng |
| Description conventions | rda |
| -- | pn |
| Transcribing agency | MiAaPQ |
| Modifying agency | MiAaPQ |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RM323.3.A68 1982 |
| 245 10 - TITLE STATEMENT | |
| Title | Possible Long-Term Health Effects of Short-Term Exposure to Chemical Agents : |
| Remainder of title | Volume 1. |
| 250 ## - EDITION STATEMENT | |
| Edition statement | 1st ed. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | Washington, D.C. : |
| Name of producer, publisher, distributor, manufacturer | National Academies Press, |
| Date of production, publication, distribution, manufacture, or copyright notice | 1982. |
| 264 #4 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | ©1982. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 online resource (298 pages) |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Content type code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media type term | computer |
| Media type code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | online resource |
| Carrier type code | cr |
| Source | rdacarrier |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | POSSIBLE LONG-TERM HEALTH EFFECTS OF SHORT-TERM EXPOSURE TO CHEMICAL AGENTS -- Copyright -- ACKNOWLEDGEMENTS -- PREFACE -- EXECUTIVE SUMMARY -- ANTICHOLINESTERASE CHEMICALS -- ANTICHOLINERGIC CHEMICALS -- MORTALITY -- MORBIDITY -- Contents -- 1 INTRODUCTION -- HISTORY OF THE EDGEWOOD TESTING PROGRAM -- PROCEDURES USED AT THE EDGEWOOD CHEMICAL TESTING PROGARM -- RECRUITMENT OF VOLUNTEERS -- GUIDELINES FOLLOWED IN THE PROTECTION OF SUBJECTS -- INVESTIGATORS -- SELECTION OF DOSES FOR HUMAN TESTS -- RANGE OF DOSES -- SAFETY MARGIN -- 2 ANTICHOLINESTERASES -- CHEMISTRY OF ANTICHOLINESTERASES -- "REVERSIBLE" INHIBITORS -- ORGANOPHOSPHORUS (OP) INHIBITORS -- ABSORPTION, FATE, AND EXCRETION OF ANTI-CHES -- MECHANISMS OF ACTION -- INHIBITION OF ACETYLCHOLINESTERASE BY ANTICHOLINESTERASES -- REACTIVATION OF ACHE -- AGING OF INHIBITED ACHE -- CHOLINERGIC RECEPTOR AND ACH CHANNEL -- PRESYNAPTIC ACTION -- NERVE MEMBRANE -- CENTRAL NERVOUS SYSTEM -- "NEUROTOXIC" ESTERASE (NTE) -- BIOCHEMICAL AND METABOLIC CHANGES -- OP ALKYLATION -- BIOLOGIC AND CLINICAL EFFECTS -- ACUTE EFFECTS: PHARMACOLOGY -- Eye -- Gastrointestinal Tract -- Actions at Other Autonomic Sites -- Neuromuscular Junction -- Brain -- ACUTE TOXIC EFFECTS -- DELAYED NEUROPATHY (CNS-PNS DISTAL AXONOPATHY) -- Clinical Features -- Neuropathologic Features -- Neuropathic Potency -- LONG-TERM BRAIN DYSFUNCTION -- JUNCTIONAL NEUROMYOPATHY -- OTHER ADVERSE HEALTH EFFECTS -- Mutagenicity -- Carcinogenicity -- Fetal and Teratogenic Effects -- Effects on Male Reproduction -- Cataractogenic Effects -- Hemocoagulation -- IMMEDIATE AND DELAYED EFFECTS IN VOLUNTEERS AFTER SINGLE OR REPEATED EXPOSURE TO ANTI-CHES AT EDGEWOOD -- MORTALITY DATA -- EVALUATION OF THE LIKELIHOOD OF LONG-TERM ADVERSE HEALTH EFFECTS -- BRAIN DYSFUNCTION -- JUNCTIONAL NEUROMYOPATHY AND DELAYED NEUROPATHY -- OTHER ADVERSE HEALTH EFFECTS. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Mutagenicity, Carcinogenicity, and Male Reproductive Effects -- Cataractogenicity -- Blood Changes -- CONCLUSIONS -- REFERENCES -- 3 ANTICHOLINERGICS -- ATROPINE, SCOPOLAMINE, AND RELATED THERAPEUTIC ANTICHOLINERGIC CHEMICALS -- SITES OF ACTION -- PERIPHERAL EFFECTS -- CENTRAL EFFECTS -- POISONING BY BELLADONNA ALKALOIDS -- SYMPTOMS AND SIGNS OF ATROPINE POISONING -- TREATMENT -- MECHANISM OF ACTION -- ABSORPTION, FATE, AND EXCRETION -- PHARMACOLOGICAL PROPERTIES OF SYNTHETIC ATROPINE DERIVATIVES -- ROLE OF DRUG DISPOSITION IN EXPLAINING DIFFERENCES AMONG ANTICHOLINERGIC COMPOUNDS -- ATROPINE -- BZ -- ANIMAL TOXICOLOGY OF ANTICHOLINERGIC COMPOUNDS -- IMMEDIATE EFFECTS -- EA 3443 -- EA 3834 -- LONG-TERM AND DELAYED EFFECTS -- Atropine -- Clidinium (Quartzan) -- Other Data -- HUMAN TOXICOLOGY OF ANTICHOLINERGIC COMPOUNDS -- DOSING CONSIDERATIONS -- Atropine -- Other Anticholinergic Compounds -- USE OF ANTIDOTES -- IMMEDIATE EFFECTS -- Peripheral and Behavioral Effects -- EEG Effects -- BZ Case Reports -- EA 3834 -- Overall Evaluation of Immediate Adverse Effects -- LONG-TERM AND DELAYED EFFECTS -- MORTALITY -- SUMMARY -- CONCLUSIONS -- REFERENCES -- 4 MORTALITY -- METHOD OF ANALYSIS -- RESULTS -- REFERENCE -- APPENDIX A MASTER FILE-ANTICHOLINESTERASE CHEMICALS -- APPENDIX B MASTER FILE-ANTICHOLINERGIC CHEMICALS -- APPENDIX C LIST OF DOCUMENTS SUPPLIED TO ANTICHOLINESTERASE PANEL -- APPENDIX D LIST OF DOCUMENTS SUPPLIED TO ANTICHOLINERGIC PANEL -- APPENDIX E CASE-FILE DATA ON EDGEWOOD SUBJECTS -- SUMMARY OF VOLUNTEER TESTING WITH GB (A1) -- SUMMARY OF VOLUNTEER TESTING WITH VX (A2) -- SUMMARY OF VOLUNTEER TESTING WITH GA (A3) -- SUMMARY OF VOLUNTEER TESTING WITH GD (A5) -- SUMMARY OF VOLUNTEER TESTING WITH DFP (A6) -- SUMMARY OF VOLUNTEER TESTING WITH EA 3148 (A7) -- SUMMARY OF VOLUNTEER TESTING WITH THA (A9), TACRINE. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | SUMMARY OF VOLUNTEER TESTING WITH PHYSOSTIGMINE (A10) -- SUMMARY OF VOLUNTEER TESTING WITH PROSTIGMINE (A11) -- SUMMARY OF VOLUNTEER TESTING WITH HEXAFLUORENIUM (MYLAXINR) (A12) -- SUMMARY OF VOLUNTEER TESTING WITH MALATHION (A14) -- SUMMARY OF VOLUNTEER TESTING WITH METHACHOLINE (A20) -- SUMMARY OF VOLUNTEER TESTING WITH URECHOLINE (A21) -- APPENDIX F EXCERPTS FROM BZ DATA -- CONTENTS -- APPENDIX G SUMMARY OF ACUTE-AND CHRONIC-TOXICITY DATA IN VARIOUS MAMMALS WITH THE ANTICHOLINERGIC TEST AGENTS (DITRAN,… -- TOXICITY -- BLOOD (RATS) -- HISTOPATHOLOGY -- OTHER DRUGS -- CONCLUSION -- APPENDIX H EVALUATION OF DATA FROM SHORT-TERM GENETIC TESTING OF ANTICHOLINERGIC CHEMICALS -- 3-QUINUCLIDINYL BENZILATE -- SCOPOLAMINE -- ATROPINE -- CONCLUSIONS -- REFERENCES -- APPENDIX I DIGEST REPORT-ANTICHOLINERGIC CHEMICALS -- INTRODUCTION -- APPENDIX I DIGEST REPORT ANTICHOLINERGIC CHEMICALS -- INTRODUCTION -- ESTERS OF TROPIC ACID -- STUDIES IN ANIMALS -- HUMAN DATA FROM THE GENERAL LITERATURE -- HUMAN DATA FROM EDGEWOOD ARSENAL -- SUMMARY -- ESTERS OF BENZILIC ACID -- STUDIES IN ANIMALS -- 3-QUINUCLIDINYL BENZILATE (BZ, EA 2277) -- DIETHYLAMINOETHYL BENZILATE -- EFFECTS ON MAN -- SUMMARY -- ESTERS OF PHENYLCYCLOPENTYLGLYCOLIC ACID -- N-METHYL-4-PIPERIDINYL-(PHENYLCYCLOPENTYL)-GLYCOLATE (EA 3443) -- DITRAN (CS 4297) -- 3-QUINUCLIDINYL-(PHENYLCYCLOPENTYL)-GLYCOLATE (EA 3167) -- L-2-ALPHA-TROPINYL-L-(PHENYLCYCLOPENTYL)-GLYCOLATE (226,086) -- 2-METHYL-3-QUINUCLIDINYL-(PHENYLCYCLOPENTYL)-GLYCOLATE (301,060) -- ESTERS OF PHENYLISOPROPYLGLYCOLIC ACID -- N-METHYL-4-PIPERIDINYL-(PHENYLISOPROPYL)-GLYCOLATE (EA 3834) -- 4-(1-METHYL-1,2,3,6-TETRAHYDROPYRIDINYL)-PHENYLISOPROPYLGLYCOLATE (302,668) -- ESTERS OF 1-PROPYNYLCYCLOPENTYLGLYCOLIC ACID -- N-METHYL-4-PIPERIDYL-(PHENYLCYCLOBUTYL)-GLYCOLATE (EA 3580) -- MISCELLANEOUS ESTERS -- 302,282 -- 302,537 -- WIN2299. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | NONESTER ANTICHOLINERGIC COMPOUNDS -- BENZETIMIDE -- MEPIPERPHENIDOL -- "TAB" MIXTURE -- DISCUSSION -- REFERENCES -- APPENDIX J ANTICHOLINERGIC DRUGS AND THE EEG -- LITERATURE REVIEW -- MILITARY DATA -- Conclusions -- REFERENCES -- APPENDIX K BIOCHEMICAL ASPECTS OF ANTICHOLINERGIC CHEMICALS -- CONCLUSION -- REFERENCES -- APPENDIX L STRUCTURE-ACTIVITY RELATIONS OF THE CENTRALLY ACTIVE ANTICHOLINERGIC AGENTS -- STEREOSPECIFICITY -- COMPARISON OF ANIMAL AND HUMAN DATA WITH VARIOUS ANTICHOLINERGIC DRUGS -- SITES OF ANTICHOLINERGIC ACTION IN BRAIN -- COMPETITION BETWEEN BEHAVIORAL POTENCY AND RECEPTOR AFFINITY -- REFERENCES. |
| 588 ## - SOURCE OF DESCRIPTION NOTE | |
| Source of description note | Description based on publisher supplied metadata and other sources. |
| 590 ## - LOCAL NOTE (RLIN) | |
| Local note | Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Chemical warfare. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cholinesterase inhibitors. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Parasympatholytic agents. |
| 655 #4 - INDEX TERM--GENRE/FORM | |
| Genre/form data or focus term | Electronic books. |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Print version: |
| Main entry heading | |
| Title | Possible Long-Term Health Effects of Short-Term Exposure to Chemical Agents |
| Place, publisher, and date of publication | Washington, D.C. : National Academies Press,c1982 |
| International Standard Book Number | 9780309077590 |
| 797 2# - LOCAL ADDED ENTRY--CORPORATE NAME (RLIN) | |
| Corporate name or jurisdiction name as entry element | ProQuest (Firm) |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://ebookcentral.proquest.com/lib/orpp/detail.action?docID=3377964">https://ebookcentral.proquest.com/lib/orpp/detail.action?docID=3377964</a> |
| Public note | Click to View |
No items available.