Pesticides in the Diets of Infants and Children. (Record no. 83809)
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| fixed length control field | 09524nam a22005173i 4500 |
| 001 - CONTROL NUMBER | |
| control field | EBC3376249 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MiAaPQ |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20240729125240.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS | |
| fixed length control field | m o d | |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr cnu|||||||| |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 240724s1993 xx o ||||0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9780309585354 |
| Qualifying information | (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Canceled/invalid ISBN | 9780309048750 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (MiAaPQ)EBC3376249 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (Au-PeEL)EBL3376249 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (CaPaEBR)ebr10055284 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (CaONFJC)MIL19660 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (OCoLC)923262265 |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | MiAaPQ |
| Language of cataloging | eng |
| Description conventions | rda |
| -- | pn |
| Transcribing agency | MiAaPQ |
| Modifying agency | MiAaPQ |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RA1225 -- .N38 1993eb |
| 082 0# - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 615.9/54 |
| 245 10 - TITLE STATEMENT | |
| Title | Pesticides in the Diets of Infants and Children. |
| 250 ## - EDITION STATEMENT | |
| Edition statement | 1st ed. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | Washington, D.C. : |
| Name of producer, publisher, distributor, manufacturer | National Academies Press, |
| Date of production, publication, distribution, manufacture, or copyright notice | 1993. |
| 264 #4 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | ©1993. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 online resource (401 pages) |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Content type code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media type term | computer |
| Media type code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | online resource |
| Carrier type code | cr |
| Source | rdacarrier |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | PESTICIDES in the DIETS OF INFANTS AND CHILDREN -- Copyright -- Preface -- Contents -- Executive Summary -- CONCLUSIONS -- Age-Related Variation in Susceptibility and Toxicity -- Age-Related Differences in Exposure -- A New Approach to Risk Assessment for Infants and Children -- RECOMMENDATIONS -- 1 Background and Approach to the Study -- PESTICIDE USE -- PESTICIDE CONTROL LEGISLATION -- APPROACH TO THE STUDY -- REFERENCES -- 2 Special Characteristics of Children -- GROWTH -- Normal Human Growth -- Human Compared to Animal Infants -- Toxicologic Implications of Growth in Cell Numbers and Size -- Toxicologic Implications of the Growth and Development of Organs -- Toxicologic Implications of Changes in Body Composition -- DEVELOPMENT -- Genetics, Development, and the Environment -- Metabolism -- Developmental Toxicity Studies -- CONCLUSIONS AND RECOMMENDATIONS -- Conclusions -- Recommendations -- REFERENCES -- 3 Perinatal and Pediatric Toxicity -- ACUTE TOXICITY -- NEUROTOXICITY -- Postnatal Effects of Neurotoxicants -- Measuring Neurotoxic Effects in Humans -- The Lead Model -- Pesticides as Neurotoxicants -- Effects of Pesticides in Children -- Levels of Pesticides Affecting Children -- Comparability of Neurotoxicity Effects in Laboratory Animals -- IMMUNOTOXICITY -- Effects of Environmental Agents on the Immune System -- Animal Studies -- Studies in Humans -- CARCINOGENESIS AND MUTAGENESIS -- Carcinogenesis in the Developing Organism -- Animal Studies -- Human Studies -- METABOLISM AND PHARMACOKINETICS -- Dermal and Pulmonary Exposure -- Oral Exposure -- Absorption -- Other Factors Affecting Oral Absorption -- Distribution and Uptake of Chemicals -- Retention -- Metabolism of Xenobiotic Compounds -- Excretion -- SCALING AND REGRESSION ANALYSIS -- Body Weight -- Other Effects of Body Size -- Surface Area -- Metabolic Rate -- Regression Analysis. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | CONCLUSIONS AND RECOMMENDATIONS -- Conclusions -- Recommendations -- REFERENCES -- 4 Methods for Toxicity Testing -- CURRENT METHODS: GENERAL CONSIDERATIONS -- ACUTE TOXICITY STUDIES -- General Description -- EPA's Proposed Changes -- SUBCHRONIC TOXICITY STUDIES -- General Description -- EPA's Proposed Changes -- CHRONIC TOXICITY STUDIES -- General Description -- EPA's Proposed Changes -- DEVELOPMENTAL TOXICITY STUDIES -- General Description -- EPA's Proposed Changes -- REPRODUCTION STUDIES -- General Description -- EPA's Proposed Changes -- MUTAGENICITY STUDIES -- General Description -- EPA's Proposed Changes -- GENERAL METABOLISM STUDIES -- General Description -- EPA's Proposed Changes -- NEUROTOXICITY STUDIES -- General Description -- EPA's Proposed Changes -- SPECIAL TESTING -- CONCLUSIONS AND RECOMMENDATIONS -- Conclusions -- Recommendations -- REFERENCES -- 5 Food and Water Consumption -- FOOD CONSUMPTION SURVEYS -- SURVEY METHODOLOGY -- Retrospective Methods -- The 24-Hour (or 1-Day) Recall Method -- Food Frequency Questionnaires -- Prospective Methods -- Food Records or Diaries -- Combined Retrospective and Prospective Methods -- Methods Used in USDA Surveys -- SURVEY DESIGN -- SAMPLE WEIGHTS -- SAMPLE SIZE -- COMPARISONS OF INTAKE DATA WITH STANDARDS -- VALIDATION OF FOOD CONSUMPTION DATA -- THE STRENGTHS AND WEAKNESSES OF THE FOOD CONSUMPTION DATA BASES IN ESTIMATING PESTICIDE EXPOSURE OF CHILDREN -- WATER INTAKE -- Dietary Sources of Water -- Water Intake Estimates -- QUANTIFICATION OF CONSUMPTION DATA -- AGE-RELATED DIFFERENCES IN DIETARY PATTERNS -- ISSUES RELATED TO THE EVALUATION OF FOOD MONITORING DATA -- Differences in Consumption Among Age Groups -- Differences in Consumption within Age Groups -- CONCLUSIONS AND RECOMMENDATIONS -- Conclusions -- Recommendations -- REFERENCES -- 6 Pesticide Residues -- SOURCES OF DATA ON USAGE. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | THE OCCURRENCE AND FATE OF PESTICIDE RESIDUES -- PESTICIDE REGISTRATION AND THE DEVELOPMENT OF ANALYTICAL METHODS -- Interregional Project Number 4 -- Universities and the ARS -- METHODS FOR SAMPLING AND ANALYSIS -- Sampling -- Analysis -- Single Residue Methods -- Multiresidue Methods -- Criteria for Selecting a Method -- Single Residue Methods or Multiresidue Methods? -- Breadth of Applicability -- Detection Limits -- Accuracy and Precision -- Speed and Cost -- Instrumentation -- Validation -- MONITORING -- Federal Activities -- State Activities -- Food Processing Industry Activities -- Private Laboratories -- QUALITY CONTROLS -- LIMITATIONS OF THE DATA -- Sources of Error -- Other Limitations -- PESTICIDES IN WATER -- Groundwater -- Surface Water -- The Importance of Water Data to Infants and Children -- PESTICIDES IN INFANT FORMULA -- Infant Formula Based on Cow's Milk -- Soy-Based Infant Formula -- Theoretical Maximum Residue Contributions -- PESTICIDES IN HUMAN MILK -- DDT and Metabolites -- Dieldrin -- Lindane -- Hexachlorobenzene -- Other Cyclodiene Pesticides -- Risks to Infants from Pesticides in Human Milk -- PESTICIDES IN FOODS -- The FDA Surveillance Data -- Number of FDA Samples -- Positive Detections -- Residue Levels -- Residue Distribution -- Effects of Processing -- Apple-Based Foods -- Infant Cereal -- CONCLUSIONS AND RECOMMENDATIONS -- Conclusions -- Recommendations -- REFERENCES -- 7 Estimating Exposures -- THE USED OF FOOD CONSUMPTION AND RESIDUE DATA FOR EXPOSURE ASSESSMENT -- Food Consumption Data -- Average Levels of Consumption -- Peak Levels of Consumption -- Residue Monitoring -- Combining Residue and Exposure Data -- LONG-TERM EXPOSURE TO BENOMYL -- The Compound -- The Consumption Data -- The Residue Data -- Estimation of Exposure -- The Manufacturer's Field Trials -- The Manufacturer's Market Basket Survey. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | FDA Surveillance Data -- The Food Industry -- A Certification Business -- Summary -- SHORT-TERM EXPOSURE TO ALDICARB -- The Compound -- Acute Effects of Dietary Aldicarb Exposure -- The Consumption Data -- The Residue Data -- Effects of Assumptions Regarding Residues Below the LOQ -- Estimating Dietary Exposure -- Summary -- MULTIPLE EXPOSURE ASSESSMENT: ORGANOPHOSPHATE INSECTICIDES -- Cholinesterase Inhibition -- Relative Potency of Organophosphates -- Food Consumption Data -- Residue Data -- Exposure Analysis -- Summary -- NONDIETARY EXPOSURE TO PESTICIDES -- Exposure via Parents -- Exposure Through Air -- Outdoor Air -- Indoor Air -- Exposure via Contaminated Surfaces -- Home-Use Products -- Pet Products -- Playground Equipment -- Exposure via Medications and Personal Products -- N,N-Diethyl-m-toluamide -- Lindane and Malathion -- Lanolin -- Occupational Exposures -- Exposure via Accidental Ingestion -- CONCLUSIONS AND RECOMMENDATIONS -- Conclusions -- Recommendations -- REFERENCES -- 8 Estimating the Risks -- GENERAL PRINCIPLES OF RISK ASSESSMENT -- Toxicological Risk Assessment -- Cancer Risk Estimation -- Additivity to Background and Low-Dose Linearity -- Nonlinearity at High Doses -- Molecular Dosimetry -- Mathematical Modeling of Cancer Risk -- Species Conversion -- Benchmark Dose -- RISK ASSESSMENT FOR INFANTS AND CHILDREN -- Pharmacokinetics -- Pregnancy, Lactation, and Nursing -- Neurotoxicity -- Multiple Exposures -- Inert Ingredients -- Considerations Specific to Children -- Exposure and Low Socioeconomic Status -- Age-Dependent Toxicity -- Genetic Susceptibility -- Polymorphism in Metabolism -- Chronic Medical Conditions -- Interactions with Medication -- Acetylcholinesterase Inhibitors -- Antiepileptic Pharmaceuticals -- Other Pharmaceuticals -- Carcinogenesis -- Factors That Might Increase Risk of Cancer Among Infants and Children. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Effects of Age-Dependent Exposures -- Consumption and Exposure Data -- CONCLUSIONS AND RECOMMENDATIONS -- Conclusions -- Recommendations -- REFERENCES -- Index. |
| 588 ## - SOURCE OF DESCRIPTION NOTE | |
| Source of description note | Description based on publisher supplied metadata and other sources. |
| 590 ## - LOCAL NOTE (RLIN) | |
| Local note | Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pediatric toxicology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pesticide residues in food -- United States. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pesticides -- Toxicology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Infant formulas -- Contamination. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Food contamination. |
| 655 #4 - INDEX TERM--GENRE/FORM | |
| Genre/form data or focus term | Electronic books. |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Print version: |
| Main entry heading | |
| Title | Pesticides in the Diets of Infants and Children |
| Place, publisher, and date of publication | Washington, D.C. : National Academies Press,c1993 |
| International Standard Book Number | 9780309048750 |
| 797 2# - LOCAL ADDED ENTRY--CORPORATE NAME (RLIN) | |
| Corporate name or jurisdiction name as entry element | ProQuest (Firm) |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://ebookcentral.proquest.com/lib/orpp/detail.action?docID=3376249">https://ebookcentral.proquest.com/lib/orpp/detail.action?docID=3376249</a> |
| Public note | Click to View |
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