Introduction To Metabolic And Cellular Engineering, An. (Record no. 65810)
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| 000 -LEADER | |
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| fixed length control field | 08662nam a22005053i 4500 |
| 001 - CONTROL NUMBER | |
| control field | EBC3050876 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MiAaPQ |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20240729124408.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS | |
| fixed length control field | m o d | |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr cnu|||||||| |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 240724s2002 xx o ||||0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9789812388773 |
| Qualifying information | (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Canceled/invalid ISBN | 9789810248352 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (MiAaPQ)EBC3050876 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (Au-PeEL)EBL3050876 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (CaPaEBR)ebr10201280 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (CaONFJC)MIL505358 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (OCoLC)922951732 |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | MiAaPQ |
| Language of cataloging | eng |
| Description conventions | rda |
| -- | pn |
| Transcribing agency | MiAaPQ |
| Modifying agency | MiAaPQ |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | TP248.3.I58 2002 |
| 082 0# - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 571 |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Aon, Miguel Antonio. |
| 245 10 - TITLE STATEMENT | |
| Title | Introduction To Metabolic And Cellular Engineering, An. |
| 250 ## - EDITION STATEMENT | |
| Edition statement | 1st ed. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | Singapore : |
| Name of producer, publisher, distributor, manufacturer | World Scientific Publishing Company, |
| Date of production, publication, distribution, manufacture, or copyright notice | 2002. |
| 264 #4 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | ©2002. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 online resource (266 pages) |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Content type code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media type term | computer |
| Media type code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | online resource |
| Carrier type code | cr |
| Source | rdacarrier |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Intro -- Contents -- Preface -- List of Abbreviations -- Introduction -- Introductory Outlines -- Metabolic and Cellular Engineering in the Context of Bioprocess Engineering -- Tools for Metabolic and Cellular Engineering -- Engineering Cells for Specific Biotransformations -- Metabolic Areas that Have Been Subjected to MCE -- From DNA Sequence to Biological Function -- Temporal and Spatial Scaling in Cellular Processes -- Scaling in Microbial and Biochemical Systems -- Views of the Cell -- Black and Grey Boxes: Levels of Description of Metabolic Behavior in Microorganisms -- Transduction and Intracellular Signalling -- Self-organized Emergent Phenomena -- Homeodynamics and Coherence -- Matter and Energy Balances -- Mass Balance -- General Formulation of Mass Balance -- Integral and Differential Mass Balances -- Growth Stoichiometry and Product Formation -- Biomass and Product Yields -- Electron Balance -- Theoretical Oxygen Demand -- Opening the "Black Box". Mass Balance as the Basis of Metabolic Flux Analysis -- Energy Balance -- Forms of Energy and Enthalpy -- Calorimetric Studies of Energy Metabolism -- Heat of Combustion -- An Energetic View of Microbial Metabolism -- Cell Growth and Metabolite Production. Basic Concepts -- Microbial Growth under Steady and Balanced Conditions -- Microbial Energetics under Steady State Conditions -- Growth Kinetics under Steady State Conditions -- The Dilution Rate -- The Dilution Rate and Biomass Concentration -- The Dilution Rate and the Growth-limiting Substrate Concentration -- Biomass and Growth-limiting Substrate Concentration at the Steady State -- Growth as a Balance of Fluxes -- The Flux Coordination Hypothesis -- Toward a Rational Design of Cells -- Redirecting Central Metabolic Pathways under Kinetic or Thermodynamic Control -- Thermodynamic or Kinetic Control of Flux under Steady State Conditions. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Kinetic and Thermodynamic Limitations in Microbial Systems. Case Studies -- Saccharomyces cerevisiae -- Escherichia coli -- Increasing Carbon Flow to Aromatic Biosynthesis in Escherichia coli -- Methods of Quantitation of Cellular "Processes Performance -- Stoichiometry of Growth: The Equivalence between Biochemical Stoichiometries and Physiological Parameters -- A General Formalism for Metabolic Flux Analysis -- A Comparison between Different Methods of MFA -- MFA Applied to Prokaryotic and Lower Eukaryotic Organisms -- MFA as Applied to Studying the Performance of Mammalian Cells in Culture -- Metabolic Fluxes during Balanced and Steady State Growth -- Bioenergetic and Physiological Studies in Batch and Continuous Cultures. Genetic or Epigenetic Redirection of Metabolic Flux -- Introduction of Heterologous Metabolic Pathways -- Metabolic Engineering of Lactic Acid Bacteria for Optimising Essential Flavor Compounds Production -- Metabolic Control Analysis -- Summation and connectivity theorems -- Control and Regulation -- The Control of Metabolites Concentration -- A Numerical Approach for Control Analysis of Metabolic Networks and Nonlinear Dynamics -- The TDA Approach as Applied to the Rational Design of Microorganisms: Increase of Ethanol Production in Yeast -- Phase I: Physiological Metabolic and Bioenergetic Studies of Different Strains of S. cerevisiae -- Phase II: Metabolic Control Analysis and Metabolic Flux Analysis of the Strain under the Conditions Defined in Phase I -- Phases III and IV: To Obtain a Recombinant Yeast Strain with an Increased Dose of PFK and to Assay the Engineered Strain in Chemostat Cultures under the Conditions Specified in Phase I -- Appendix A -- A Simplified Mathematical Model to Illustrate the Matrix Method of MCA -- Appendix B. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Conditions for Parameter Optimization and Simulation of the Mathematical Model of Glycolysis -- Dynamic Aspects of Bioprocess Behavior -- Transient and Oscillatory States of Continuous Culture -- Mathematical Model Building -- Transfer-Function Analysis and Transient-Response Techniques -- Theoretical Transient Response and Approach to Steady State -- Transient Responses of Microbial Cultures to Perturbations of the Steady State -- Dilution Rate -- Feed Substrate Concentration -- Growth with Two Substrates -- Temperature -- Dissolved Oxygen -- The Meaning of Steady State Performance in Chemostat Culture -- Oscillatory Phenomena in Continuous Cultures -- 1. Oscillations as a Consequence of Equipment Artifacts -- 2. Oscillations Derived from Feedback Between Cells and Environmental Parameters -- 3. Oscillations Derived from Intracellular Feedback Regulation -- 4. Oscillations Derived from Interactions between Different Species in Continuous Culture -- 5. Oscillations Due to Synchronous Growth and Division -- Bioprocess Development with Plant Cells -- MCE in Plants: Realities and Potentialities -- Plant Transformation for Studies on Metabolism and Physiology -- Improving Plants through Genetic Engineering -- Improving Plant Resistance to Chemicals Pathogens and Stresses -- Improving Quality and Quantity of Plant Products -- Using Plant Genetic Engineering to Produce Heterologous Proteins -- Tools for the Manipulation and Transformation of Plants -- Plant Metabolism: Matter and Energy Flows and the Prospects of MCA -- Metabolic Compartmentation in Plant Cells -- Carbon Assimilation Partitioning and Allocation -- Carbon Fixation in Higher Plants -- MCA Studies in Plants -- Regulation and Control: Starch Synthesis a Case Study -- Concluding Remarks -- Cellular Engineering -- Outline -- The Global Functioning of Metabolic Networks. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | The Nature of the Carbon Source Determines the Activation of Whole Blocks of Metabolic Pathways with Global Impact on Cellular Energetics -- Carbon Sources that Share Most Enzymes Required to Transform the Substrates into Key Intermediary Metabolites under Similar Growth Rates Bring About Similar Fluxes through the Main Amphibolic Pathways -- Interaction between Carbon and Nitrogen Regulatory Pathways in S. cerevisiae -- Flux Redirection toward Catabolic (Fermentation) or Anabolic (Carbohydrates) Products May Be Generated as a Result of Alteration in Redox and Phosphorylation Potentials -- Temperature-Dependent Expression of Certain Mutations Depend upon the Carbon Source -- There Seems to Exist a General Pattern of Control of the Intracellular Concentration of Metabolites -- Dependence of the Control of Glycolysis on the Genetic Background and the Physiological Status of Yeast in Chemostat Cultures -- Cellular Engineering -- Growth Rate Gl Phase of the Cell Cycle Production of Metabolites and Macromolecules as Targets for Cellular Engineering -- Catabolite Repression and Cell Cycle Regulation in Yeast -- Protein Production as a Function of Growth Rate -- The Selective Functioning of Whole Metabolic Pathways Is Permissive for Differentiation -- Bibliography -- Index. |
| 588 ## - SOURCE OF DESCRIPTION NOTE | |
| Source of description note | Description based on publisher supplied metadata and other sources. |
| 590 ## - LOCAL NOTE (RLIN) | |
| Local note | Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Biochemical engineering. |
| 655 #4 - INDEX TERM--GENRE/FORM | |
| Genre/form data or focus term | Electronic books. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Cortassa, Sonia Del Carmen. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Iglesias, Alberto Alvaro. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lloyd, David. |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Print version: |
| Main entry heading | Aon, Miguel Antonio |
| Title | Introduction To Metabolic And Cellular Engineering, An |
| Place, publisher, and date of publication | Singapore : World Scientific Publishing Company,c2002 |
| International Standard Book Number | 9789810248352 |
| 797 2# - LOCAL ADDED ENTRY--CORPORATE NAME (RLIN) | |
| Corporate name or jurisdiction name as entry element | ProQuest (Firm) |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://ebookcentral.proquest.com/lib/orpp/detail.action?docID=3050876">https://ebookcentral.proquest.com/lib/orpp/detail.action?docID=3050876</a> |
| Public note | Click to View |
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