Aneuploidy : (Record no. 61514)
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| fixed length control field | 08492nam a22004933i 4500 |
| 001 - CONTROL NUMBER | |
| control field | EBC3022257 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MiAaPQ |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20240729124157.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS | |
| fixed length control field | m o d | |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr cnu|||||||| |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 240724s2012 xx o ||||0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781621002154 |
| Qualifying information | (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Canceled/invalid ISBN | 9781621000709 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (MiAaPQ)EBC3022257 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (Au-PeEL)EBL3022257 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (CaPaEBR)ebr10700434 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (OCoLC)923668350 |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | MiAaPQ |
| Language of cataloging | eng |
| Description conventions | rda |
| -- | pn |
| Transcribing agency | MiAaPQ |
| Modifying agency | MiAaPQ |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | QH461 -- .A54 2012eb |
| 082 0# - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 616/.042 |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Rossi, Salvatore de. |
| 245 10 - TITLE STATEMENT | |
| Title | Aneuploidy : |
| Remainder of title | Etiology, Disorders and Risk Factors. |
| 250 ## - EDITION STATEMENT | |
| Edition statement | 1st ed. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | Hauppauge : |
| Name of producer, publisher, distributor, manufacturer | Nova Science Publishers, Incorporated, |
| Date of production, publication, distribution, manufacture, or copyright notice | 2012. |
| 264 #4 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | ©2012. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 online resource (185 pages) |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Content type code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media type term | computer |
| Media type code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | online resource |
| Carrier type code | cr |
| Source | rdacarrier |
| 490 1# - SERIES STATEMENT | |
| Series statement | Genetics - Research and Issues |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Intro -- ANEUPLOIDY: ETIOLOGY, DISORDERS AND RISK FACTORS -- ANEUPLOIDY: ETIOLOGY, DISORDERS AND RISK FACTORS -- LIBRARY OF CONGRESS CATALOGING-IN-PUBLICATION DATA -- Contents -- Preface -- Chapter I: Aneuploidy: Mechanisms, Cancer and the Role of Environmental Pollutants -- Wise Laboratory of Environmental and Genetic Toxicology, -- Maine Center for Toxicology and Environmental Health, University of Southern Maine -- Department of Applied Medical Science, -- University of Southern Maine, Portland, ME, US -- Abstract -- Introduction -- Centrosomes -- Centrosome Duplication Cycle -- Centrosome Amplification and Cancer -- Mechanisms of Centrosome Amplification -- Spindle Assembly Checkpoint -- Mechanism of the Spindle Assembly Checkpoint -- Spindle Assembly Checkpoint Defects and Cancer -- Kinetochores -- Kinetochore Structure and Function -- Kinetochore Dysfunction and Cancer -- Sister Chromatid Cohesion -- Mechanism of Sister Chromatid Cohesion -- Sister Chromatid Cohesion Defects and Cancer -- Hexavalent Chromium: -- An Aneugenic Environmental and Occupational Carcinogen -- Conclusion -- References -- Chapter II: Ploidy in Mitosis and Meiosis: A Role of MAPK/Erk Network -- EA4479 Laboratoire de Régulation des Signaux de Division University of Lille 1, Cell Signalomics Group, Parc de la Haute Borne, France -- Abstract -- 1. Crucial to Cell Integrity, Genomic Stability Is Controlled Throughout Cell Cycle -- 1.1. Genomic Stability -- 1.2. Failures in the Mitotic Machinery -- 2. MAPK Network Members Are Involved in Genomic Stability -- 2.1. MAPK, a Node in a Network for Signal Integration -- 2.2. Requirement for MAPK/Erk in G2/M Progression in -- Mitotic Models -- 2.3. Antagonistic Effects of Erk Pathway: Towards Genomic Integrity -- 3. MAPK Pathway in G2/M, Lessons from Vertebrates Gametes. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 3.1. MAPK Activation in the South African Clawed Xenopus Oocytes, a Case of Study for Physical Properties of MAPK Activation -- 3.2. Role of MAPK/Erk Network in Spindle Organization -- 4. Mos, Particularities of a MAPKKK in Tumor Cells and Gametes -- 4.1. Transformation and Aneuploidy Driven By Mos -- 4.2. Number of M Phases Cycles: Does Mos Rule the Limits? -- Concluding Remarks -- Acknowledgments -- References -- Chapter III: The Spindle Assembly Checkpoint and Aneuploidy -- 1Centro de Investigação em Ciências da Saúde (CICS), Instituto Superior de Ciências da Saúde - Norte, CESPU, Gandra PRD, Portugal -- 2Life and Health Sciences Research Institute (ICVS), Health Sciences School, University of Minho, Braga, Portugal -- 3Molecular Oncology Research Center, Barretos Cancer Hospital, -- Barretos, São Paulo, Brazil -- 4Centro de Química Medicinal da Universidade do Porto (CEQUIMED-UP), Porto, Portugal -- Abstract -- Introduction -- The Molecular Mechanism of SAC -- SAC Relevance to Aneuploidy and Cancer -- Mouse Models Link SAC Dysfunction, Aneuploidy and Cancer -- SAC Components and Perspectives in Anticancer Therapy -- Conclusion -- Acknowledgments -- References -- Chapter IV: The Role of Centromere Cohesion and Associated Proteins in Alzheimer's Disease: A Relation to Aneuploidy? -- 1Institute of Pharmaceutical Research Galenika, Belgrade, Serbia -- 2Department of Pathology, Case Western University, Cleveland, OH, US -- 3 Faculty of Pharmacy, Institute of Physiology, Department of Biology and Human Genetics, University of Belgrade, Belgrade, Serbia -- 4Laboratory of Molecular Biology and Endocrinology, Institute of Nuclear Sciences ''Vinca'', University of Belgrade, Belgrade, Serbia -- Abstract -- Introduction -- Alteration of Cohesion and Cohesion Related Proteins in Alzheimers Disease Lead to Aneuploidy?. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Cohesin Associated Proteins and Chromosome Stability -- CDK 11 A New Cell Cycle Cyclin in Cohesion Dynamics and APP -- Conclusion -- Acknowledgment -- References -- Chapter V: Cohesins, Genomic Stability, and Cancer -- Cell Proliferation and Development Program, Chromosome Dynamics in Meiosis Laboratory. Centro de Investigaciones Biológicas (CSIC), Madrid, Spain -- Summary -- Introduction -- Cohesins, Chromosome -- Instability and Cancer -- Cohesins, DNA-Damage Repair and Cancer -- Cohesins, Chromosome Segregation and Cancer -- Cohesin Complex Subunits -- Cohesin-Regulators: Cohesion Establishment and Maintaining -- Cohesin-Regulators: Cohesion Dissolution -- Concluding Remarks -- Acknowledgments -- References -- Chapter VI: Adult Neurogenesis and Aneuploidy in Etiology, Pathogenesis and Pathology of Alzheimer's Disease -- School of Biotechnology, Dublin City University, -- Glasnevin, Dublin, Ireland -- Abstract -- Introduction -- Amyloid Plaques, Neurofibrillary -- Tangles and Causative Factors of Alzheimer's Disease -- Aneuploidy in Alzheimer's Disease -- Adult Neurogenesis and Neural Stem Cells -- Neurogenesis and Aneuploid Newly Generated Neuronal Cells in Alzheimer's Disease -- Conclusion and Perspectives -- References -- Chapter VII: Aneuploidy in Cultured Human Multipotent Mesenchymal Stromal Cells -- Research Centre for Medical Genetics, Russian Academy of Medical Sciences, Russia -- Abstract -- Introduction -- Materials and Methods -- Cell Extraction and Cultivation -- MSCs Characterization -- Cytogenetic Analysis -- Results and Discussion -- Conclusion -- References -- Chapter VIII: Somatic and Germ Cell Spontaneous Aneuploidy Level in Healthy Fertile People -- Abstract -- Introduction -- Blood Cell Spontaneous Aneuploidy -- Polar Bodies Aneuploidy -- Sperm Aneuploidy -- Aim -- Materials and Methods -- Investigated groups. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Karyotyping and Blood Cells Preparation -- Semen Preparation -- Polar Bodies Preparation -- FISH Analysis -- Scoring Criteria of FISH Signals -- Statistical Analysis -- Results and Discussion -- Comparison of Cultivated and Uncultivated Cells as well as Direct and Indirect Labeling -- Sperm and Lymphocyte Aneuploidy in Men -- Polar Body Aneuploidy -- Conclusions -- References -- Chapter IX: Sperm Aneuploidy and Male Fertility -- Abstract -- Estimation of Aneuploidy Frequency in Spermatozoa -- 1. The Occurrence of Sperm Aneuploidy in Fertile Men is Varying with Male Age, Life Style, and Chemicals Exposure -- 2. The Occurrence of Sperm Aneuploidy in Infertile Men Is Higher than Those of Fertile Men -- 3. Some Chromosomes Showing Higher Incidences of Aneuploidy than the Other Chromosomes -- 4. Sex Chromosomes Showing Higher Incidences of Aneuploidy than the Autosomes and Most of these Errors Ocurrs in Meiosis I -- Chromosomal Abnormalities and Fertility Risk -- Genetic Control of Aneuploidy -- Characteristics of Aneuploid Spermatozoa and New Trends to Overcome Infertility Problem -- Conclusion -- References -- Index. |
| 588 ## - SOURCE OF DESCRIPTION NOTE | |
| Source of description note | Description based on publisher supplied metadata and other sources. |
| 590 ## - LOCAL NOTE (RLIN) | |
| Local note | Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Aneuploidy. |
| 655 #4 - INDEX TERM--GENRE/FORM | |
| Genre/form data or focus term | Electronic books. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bianchi, Filippo. |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Print version: |
| Main entry heading | Rossi, Salvatore de |
| Title | Aneuploidy: Etiology, Disorders and Risk Factors |
| Place, publisher, and date of publication | Hauppauge : Nova Science Publishers, Incorporated,c2012 |
| International Standard Book Number | 9781621000709 |
| 797 2# - LOCAL ADDED ENTRY--CORPORATE NAME (RLIN) | |
| Corporate name or jurisdiction name as entry element | ProQuest (Firm) |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | Genetics - Research and Issues |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://ebookcentral.proquest.com/lib/orpp/detail.action?docID=3022257">https://ebookcentral.proquest.com/lib/orpp/detail.action?docID=3022257</a> |
| Public note | Click to View |
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