Metabolomics : (Record no. 61411)
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| fixed length control field | 10178nam a22005173i 4500 |
| 001 - CONTROL NUMBER | |
| control field | EBC3021902 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MiAaPQ |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20240729124154.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS | |
| fixed length control field | m o d | |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr cnu|||||||| |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 240724s2010 xx o ||||0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781621000402 |
| Qualifying information | (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Canceled/invalid ISBN | 9781616680060 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (MiAaPQ)EBC3021902 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (Au-PeEL)EBL3021902 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (CaPaEBR)ebr10686225 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (OCoLC)759117255 |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | MiAaPQ |
| Language of cataloging | eng |
| Description conventions | rda |
| -- | pn |
| Transcribing agency | MiAaPQ |
| Modifying agency | MiAaPQ |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | QP171 -- .M3823 2011eb |
| 082 0# - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 612.3/9 |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Knapp, Justin S. |
| 245 10 - TITLE STATEMENT | |
| Title | Metabolomics : |
| Remainder of title | Metabolites, Metabonomics, and Analytical Technologies. |
| 250 ## - EDITION STATEMENT | |
| Edition statement | 1st ed. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | Hauppauge : |
| Name of producer, publisher, distributor, manufacturer | Nova Science Publishers, Incorporated, |
| Date of production, publication, distribution, manufacture, or copyright notice | 2010. |
| 264 #4 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | ©2011. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 online resource (277 pages) |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Content type code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media type term | computer |
| Media type code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | online resource |
| Carrier type code | cr |
| Source | rdacarrier |
| 490 1# - SERIES STATEMENT | |
| Series statement | Genetics - Research and Issues |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Intro -- METABOLOMICS: METABOLITES, METABONOMICS, AND ANALYTICAL TECHNOLOGIES -- METABOLOMICS: METABOLITES, METABONOMICS, AND ANALYTICAL TECHNOLOGIES -- LIBRARY OF CONGRESS CATALOGING-IN-PUBLICATION DATA -- CONTENTS -- PREFACE -- Chapter 1 CORRELATIONS- AND DISTANCES-BASED APPROACHES TO STATIC ANALYSIS OF THE VARIABILITY IN METABOLOMIC DATASETS. APPLICATIONS AND COMPARISONS WITH OTHER STATIC AND KINETIC APPROACHES -- Abstract -- I. Introduction -- II. Diversity and Intrinsic Variability of Metabolomic Datasets -- II.1. Presentation of Metabolomic Datasets -- II.2. Repeated Experiments for Highlighting of Metabolic States -- III. General presentation of Different Metabolomic Approaches and Parameters -- III.1. Classification of Metabolomic Approaches Based on Different Criteria -- III.2. Boolean Matrix Based Approaches -- III.3. Transition Matrix Based Approaches -- III.4. Stoichiometric Matrix Based Approaches -- III.5. Jacobian Matrix Based Approach -- III.6. Scheffe Matrix Based Approach -- IV. Metabolomic Approaches Based on Distance and Correlation Matrices -- IV.1. Correlation Based Approaches -- IV.1.1. Graphical Identification of Correlation Models -- IV.1.2. Data Transformation to Application of Linear Model -- IV.1.3. Correlation Coefficient Computation -- IV.1.3.1. Pearson Correlation Computation -- IV.1.3.2. Matrix Correlation Computation -- IV.1.3.3. Spearman Correlation Calculation -- IV.1.4. Origins and Interpretation of Correlations in Metabolic Systems -- IV.1.4.1. Chemical Equilibrium -- IV.1.4.2. Mass Conservation -- IV.1.4.3. Assymetric Control -- IV.1.4.4. Unusually High Variance in the Expression of a Single Gene -- IV.1.5. Scale-Dependent Interpretations of Correlations -- IV.1.6. Multidimensional Correlation Screening by Means of Principle Component Analysis -- IV.1.6.1. Aim -- IV.1.6.2. General Principle of PCA. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | IV.1.6.3. Computation of Eigenvalues, Eigenvectors and Principle Components -- IV.1.6.4. Graphical Interpretation of Factorial Plans -- IV.1.6.5. Different Types of PCA -- IV.1.6.6. Numerical Application and Interpretation of Standardized PCA -- IV.2. Distance Matrix-Based Approach: Cluster Analysis -- IV.2.1. Introduction -- IV.2.2 Goal of Cluster Analysis -- IV.2.3. General Protocols in Hierarchical Cluster Analysis (HCA) -- IV.2.4. Dissimilarity Measures -- IV.2.4.1. Continuous Data and Distance Computation -- IV.2.4.1.1. Euclidean Distance -- IV.2.4.1.2. Chi-Square Distance -- IV.2.4.2. Qualitative Variables and Similarity Indices -- IV.2.5. Clustering Techniques -- IV.2.5.1. Single Link-Based Clustering -- IV.2.5.2. Complete Link-Based Clustering -- IV.2.5.3. Centroid Link-Based Clustering -- IV.2.5.4. Average Link-Based Clustering -- IV.2.5.5. Variance Criterion Clustering: Ward Method -- IV.2.6. Identification and Interpretation of Clusters from Dendrogram -- V. Outlier Analyses -- V.1. Introduction -- V.2. Different Types of Outliers -- V.3. Statistical Criteria for Identification of Outliers -- V.4. Graphical Identification of Univariate Outliers -- V.5. Graphical Identification of Bivariate Outliers -- V.6. Identification of Multivariate Outliers Based on Distance Computations -- V.6.1. Standard Mahalanobis Distance Computation -- V.6.2. Jackknifed Mahalanobis Distance Computation -- V.6.3. Outlier Screening from Correspondence Analysis -- V.6.3.1. General Concepts of Correspondence Analysis -- V.6.3.2 Basic Computations in Correspondence Analysis -- V.6.3.3. Graphical Interpretation of CA Results and Outlier Diagnostic -- V.6.4. Outlier Diagnostic Based on Andrews Curves -- V.6.4.1. General Concepts -- V.6.4.2. Computation of Andrews Curves -- V.6.4.3. Graphical Outlier Diagnostic Based on Andrews Curves -- References. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Chapter 2 METABOLOMIC PROFILE AND FRACTAL DIMENSIONS IN BREAST CANCER CELLS -- Abstract -- Introduction -- Metabolomics and Cancer -- Cancer Metabolism -- Metabolism and Cancer: Cause or Epiphenomenon? -- Phenotype Metabolism, Cell Shape and Microenvironment -- Cancer Cell Shape -- Cell Shape and Metabolic Phenotype -- Conclusion -- References -- Chapter 3 FROM METABOLIC PROFILING TO METABOLOMICS: FIFTY YEARS OF INSTRUMENTAL AND METHODOLOGICAL IMPROVEMENTS -- Abstract -- Introduction -- Origins and Development: Looking Back -- Chromatographic Separation Techniques - Mass Spectrometry -- GC-MS -- Sample Preparation -- GC-MS Analysis -- LC-MS -- Sample Preparation -- LC-MS Analysis -- Direct Infusion MS and MS/MS -- Desorption and Imaging MS -- Data Handling -- Future Perspectives -- References -- Chapter 4 PLANT ENVIRONMENTAL METABOLOMICS -- Introduction -- Environment - Abiotic Interactions -- Nitrogen Deposition -- Nutrient Deficiency -- Salinity -- Drought -- Metals and Soil Pollution -- Atmospheric Carbon Dioxide (CO2) -- Ozone -- Photoperiod -- UltraViolet Radiation -- Temperature -- Ecology -- Herbivory -- Competition -- Floral Scents -- Populations, Evolution and Genetics -- Genetic versus Environmental Influences on the Metabolome -- Populations -- Conclusion -- Abbreviations -- References -- Chapter 5 MICROBIAL METAGENOMICS: CONCEPT, METHODOLOGY AND PROSPECTS FOR NOVEL BIOCATALYSTS AND THERAPEUTICS FROM THE MAMMALIAN GUT MICROBIOME -- Abstract -- Introduction -- The Concept of Genomics in Microbial Ecology -- What is Metagenomics? -- Microbial Metagenomics: Major Procedural Steps -- Sampling and Microbial Nucleic Acids Extraction -- Microbial Genome- and Gene-Enrichment -- Metagenome Cloning and Targeting -- Screening and Analysis of Metagenomic Libraries -- The Function-Driven Analysis -- The Sequence-Driven Analysis. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Genomics in Mammalian Gut Microbial Diversity -- Metagenomics in Rumen Microbiome-Motives and Applications -- 1. Rumen Microbes as Sources of Valuable Hydrolytic Enzymes -- 2. Direct Fed Microbials (DFM) from the Rumen -- 3. Rumen-Originated Antimicrobial Products -- 4. Lowering Methane Emissions -- 5. Determining the Protozoal Ecology of the Rumen -- 6. Genes and Genetic Engineering Tools from Rumen Microbiome -- Bottlenecks of the Technology -- Conclusion -- References -- Chapter 6 NUTRIGENOMICS, METABOLOMICS AND METABONOMICS: EMERGING FACES OF MOLECULAR GENOMICS AND NUTRITION -- Abstract -- Introduction -- Nutrigenomics Concept -- Nutrient-Gene Interaction -- Nutrigenomics in Livestock Perspective -- What is Metabolomics? -- Techniques and Data Analysis in Metabolomics -- What Is Metabonomics? -- Sample Analysis and Data Processing in Metabonomics -- Conclusion -- References -- Chapter7MACHINERECONSTRUCTIONOFMETABOLICNETWORKSFROMMETABOLOMICDATATHROUGHSYMBOLIC-STATISTICALLEARNING -- Abstract -- 1.Introduction -- 2.MetabolicPathways -- 3.TheSymbolic-StatisticalFrameworkPRISM -- 4.ModelingBisphenolADegradationPathwayinPRISM -- 5.ReconstructingPathwaysfromSequencesofReactions -- 6.RelatedWork -- 7.ConclusionandFutureWork -- References -- Chapter 8 METABOLOMICS -- Introduction to Metabolomics -- A. General Information on Metabolomics -- B. Database and Tool in Metabolomics -- MSFACTs [13] -- HybGFS [14] -- HMDB [15] -- aMAZE LightBench [16] -- BioSilico [17] -- Eco Cyc [18 - 21] -- Patikaweb [22] -- PathAligner [23] -- MetaCys [24 - 26] -- Golm Metabolome Database [27] -- C. Application of Metabolomics -- 1. Application in Oncology -- 2. Application in Pharmacology -- 3. Application in Genetics -- Pathway and Metabolism -- A. What is Metabolism? -- B. Pathway Drawing -- 1. PathFinder [42] -- 2. MetaViz [43]. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 3. FluxAnalyzer [44] -- 4. ePath3D -- C. Usefulness of Pathway Analysis -- D. Pathway Analysis Tool -- 1. Pathway Miner [53] -- 2. WholePathwayScope [54] -- 3. ArrayxPath [55] -- 4. Genome Expression Pathway Analysis Tool [56] -- Introduction to Metabolonics -- References -- Chapter 9 THE ROLE OF SPECIFIC ESTROGEN METABOLITES IN THE INITIATION OF BREAST AND OTHER HUMAN CANCERS -- Introduction -- Catechol Estrogen Quinones as Mutagens Initiating Breast, Prostate and Other Human Cancers -- Imbalance in Estrogen Homeostasis -- The Kidney of Syrian Golden Hamsters -- The Mammary Gland of ERKO/Wnt-1 Mice -- The Prostate of Noble Rats -- The Breast of Women with Breast Carcinoma -- Estrogen-Induced Mutations and Cell Transformation -- Conclusions -- Acknowledgments -- References -- INDEX. |
| 588 ## - SOURCE OF DESCRIPTION NOTE | |
| Source of description note | Description based on publisher supplied metadata and other sources. |
| 590 ## - LOCAL NOTE (RLIN) | |
| Local note | Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Metabolism -- Regulation. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Functional genomics. |
| 655 #4 - INDEX TERM--GENRE/FORM | |
| Genre/form data or focus term | Electronic books. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Cabrera, William L. |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Print version: |
| Main entry heading | Knapp, Justin S. |
| Title | Metabolomics: Metabolites, Metabonomics, and Analytical Technologies |
| Place, publisher, and date of publication | Hauppauge : Nova Science Publishers, Incorporated,c2010 |
| International Standard Book Number | 9781616680060 |
| 797 2# - LOCAL ADDED ENTRY--CORPORATE NAME (RLIN) | |
| Corporate name or jurisdiction name as entry element | ProQuest (Firm) |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | Genetics - Research and Issues |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://ebookcentral.proquest.com/lib/orpp/detail.action?docID=3021902">https://ebookcentral.proquest.com/lib/orpp/detail.action?docID=3021902</a> |
| Public note | Click to View |
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