Neural Mechanisms of Addiction. (Record no. 4670)
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| fixed length control field | 11025nam a22004933i 4500 |
| 001 - CONTROL NUMBER | |
| control field | EBC5501834 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MiAaPQ |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20240724113326.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS | |
| fixed length control field | m o d | |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr cnu|||||||| |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 240724s2018 xx o ||||0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9780128123317 |
| Qualifying information | (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Canceled/invalid ISBN | 9780128122020 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (MiAaPQ)EBC5501834 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (Au-PeEL)EBL5501834 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (CaPaEBR)ebr11603401 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (OCoLC)1051141328 |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | MiAaPQ |
| Language of cataloging | eng |
| Description conventions | rda |
| -- | pn |
| Transcribing agency | MiAaPQ |
| Modifying agency | MiAaPQ |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RC341 .N487 2019 |
| 082 0# - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 616.8 |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Torregrossa, Mary. |
| 245 10 - TITLE STATEMENT | |
| Title | Neural Mechanisms of Addiction. |
| 250 ## - EDITION STATEMENT | |
| Edition statement | 1st ed. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | San Diego : |
| Name of producer, publisher, distributor, manufacturer | Elsevier Science & Technology, |
| Date of production, publication, distribution, manufacture, or copyright notice | 2018. |
| 264 #4 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | ©2019. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 online resource (308 pages) |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Content type code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media type term | computer |
| Media type code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | online resource |
| Carrier type code | cr |
| Source | rdacarrier |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Front Cover -- Neural Mechanisms of Addiction -- Copyright -- Contents -- Contributors -- Chapter 1: Introduction to the Neural Basis of Addiction -- Chapter 2: Animal Models of Addiction -- Introduction -- Volitional Control Over Drug Exposure -- Pavlovian Models of Rewarding and Aversive Drug Effects -- Models of Drug-Induced Interoceptive Effects and Affective States -- Consummatory and Quasiinstrumental Models of Drug Reinforcement -- Instrumental Models of Drug Reinforcement -- Models of Excessive Drug Intake -- Models of Compulsive and Habitual Drug Taking and Drug Seeking -- Models of Cue-Induced Drug Seeking -- Models of Cue-Induced Drug Relapse -- Models of Stress-Induced Drug Relapse -- Models of Drug-Primed Drug Relapse -- Models of Cocaine Seeking Following Abstinence -- Conclusion -- Acknowledgments -- References -- Chapter 3: Transcriptional and Epigenetic Regulation of Reward Circuitry in Drug Addiction -- Introduction -- Models of Addiction -- The Reward Circuitry -- Transcription Factors Involved in Addiction -- CREB -- SRF -- NF-κB -- MEF2 -- ΔFosB -- Additional Transcription Factors -- Epigenetic Mechanisms -- Posttranslational Histone Modifications -- DNA methylation -- Conclusions -- References -- Chapter 4: Neural Circuit Plasticity in Addiction -- Introduction -- Ventral Tegmental Area -- Structure, Function, and Anatomical Connectivity -- Excitatory Plasticity -- Timeline of VTA Excitatory Plasticity -- Mechanisms Underlying VTA Excitatory Plasticity -- Inhibitory Plasticity -- Timeline of VTA Inhibitory Plasticity -- Mechanisms Underlying VTA Inhibitory Plasticity -- Nucleus Accumbens -- Structure, Function, and Anatomical Connectivity -- Time-Dependent Plasticity in the NAc: An Overview -- Acute Exposure and Withdrawal -- Repeated Exposure and Withdrawal -- Short-Term Synaptic Plasticity Associated With Relapse. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Afferent- and Cell-Specific Plasticity -- Presynaptic Plasticity -- NAc Shell -- NAc core -- Postsynaptic Plasticity -- Cortico-Accumbens Plasticity -- Allocortical-Accumbens Plasticity -- Relevance of Long- and Short-Term Accumbens Plasticity -- Cortico-Accumbens Plasticity -- Accumbens Microcircuit Plasticity -- Potential Targets for Opioid Dependence and Relapse -- Prefrontal Cortex -- Structure, Function, and Physiology -- Drug-Induced Adaptations in the mPFC -- Effects on Pyramidal Neuron Activity -- Excitatory and Inhibitory Plasticity -- Pathway-Specific Plasticity -- Alterations in Ionic Conductance in mPFC Neurons -- Short-Term Plasticity -- Summary -- References -- Chapter 5: Glutamatergic Neuroplasticity in Addiction -- Introduction -- Animal Models of Relapse -- The Neurocircuitry of Addiction -- Glutamatergic Alterations Induced by Chronic Drug Use -- GLT-1 -- Cocaine -- Nicotine -- Ethanol -- Heroin -- xCT -- Cocaine -- Nicotine -- Ethanol -- Heroin -- mGlu2/3 -- Cocaine -- Nicotine -- Ethanol -- Heroin -- mGlu5 -- Cocaine -- Nicotine -- Ethanol -- Heroin -- AMPA Receptor Subunit 1 and 2 (GluA1/2) -- Cocaine -- Nicotine -- Ethanol -- Heroin -- NMDA Receptors -- Cocaine -- Nicotine -- Ethanol -- Heroin -- Glutamatergic Pharmacotherapies for Relapse Prevention -- GLT and xCT Targets -- Ceftriaxone -- N-Acetylcysteine (NAC) -- Augmentin -- AMPAR and NMDAR Targets -- mGluR Targets -- Clinical Evidence of Glutamatergic Neuroplasticity in Addiction -- Conclusion -- References -- Chapter 6: Fos-Expressing Neuronal Ensembles in Addiction Research -- Neuronal Ensembles in Addiction -- Behavioral Models Used to Study Ensembles in Addiction Research -- Techniques Used to Study Neuronal Ensembles in Addiction Research -- Striatal Neuronal Ensembles Mediate Learned Behaviors in Addiction Research Models. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Prefrontal Cortex Neuronal Ensembles Mediate Learned Behaviors in Addiction Research Models -- Amygdala Neuronal Ensembles Mediate Learned Behaviors in Addiction Research Models -- General Conclusions About Fos-Expressing Neuronal Ensembles in Addiction Research -- Unique Gene Expression Alterations Within Fos-Expressing Neuronal Ensembles -- Unique Electrophysiological Alterations Within Fos-Expressing Neuronal Ensembles -- Unique Dendritic Spine Alterations on Fos-Expressing Neuronal Ensembles -- Fos-Expressing Neuronal Ensembles are Likely a Subset of All Neurons Activated During Behavior or Memory Recall -- Manipulating Fos-Expressing Neuronal Ensembles to Treat Human addiction? -- Conflict of Interest -- Acknowledgments -- References -- Chapter 7: Interoceptive Stimulus Effects of Drugs of Abuse -- Body Perception and Emotional Processing -- Interoception, Drug Consumption, and the Insula -- Drug Craving as Interoception -- Operant Conditioning of Interoception -- Pavlovian Conditioning of Interoception -- Interactions of Interoception and Self-Administration -- Closing Reflections: Interoception and Intervention -- Acknowledgments -- References -- Chapter 8: Maladaptive Memory Mechanisms in Addiction and Relapse -- Introduction -- Animal Models of Relapse -- Neuroanatomical Basis for Maladaptive Memory and Relapse -- Neuroanatomical Basis of Reinstatement -- Neuroanatomical Basis of Incubation of Craving -- Neuroanatomical Basis for Maladaptive Habit Memory in Addiction -- Neural Mechanisms Underlying Maladaptive Memory and Relapse -- Molecular Mechanisms of Drug-Associated Memory Formation and Maintenance -- Molecular Mechanisms of Incubation of Craving -- Neuronal Ensembles as an Emerging Model of Drug-Associated Memory Formation -- Emerging Strategies for Relapse Prevention -- Extinction as a Memory Process that Opposes Relapse. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Molecular Mechanisms Underlying Extinction -- Bidirectional Targeting of Reconsolidation and Extinction -- Translational Approaches for Enhancing Extinction/Inhibiting Reconsolidation -- Brain Stimulation -- Summary -- References -- Chapter 9: Neural Morphology and Addiction -- Dendritic Spines -- Actin Cycling in Dendritic Spines -- Approaches to Analyze Cell Morphology -- Alcohol -- Psychostimulants -- Opioids -- Inhalants -- Limitations and Future Directions -- References -- Chapter 10: Mechanisms Regulating Compulsive Drug Behaviors -- Introduction -- Impulsivity and Compulsivity -- Preclinical Compulsive Drug Models -- Escalation of Drug Intake as a Model of Compulsive Drug Taking -- Three-Criteria Addiction-like Behavior -- Compulsive Drug Seeking in the Face of Probabilistic Punishment -- Chronic Self-Administration and Incubated Drug Craving -- Theories of Compulsivity -- Opponent Process Theory -- Aberrant Habitual Learning Theory of Compulsive Drug Behavior -- Incentive Sensitization Theory of Drug Addiction -- Inhibitory Control -- Neural Circuitry -- Prefrontal Cortex -- Ventral and Dorsal Striatum -- Extended Amygdala -- Neurotransmission -- Dopamine -- Glutamate -- Serotonin -- Pro- and Antistress Neurotransmitter Systems -- Epigenetic Mechanisms of Compulsive-Related Behaviors -- Chromatin Dynamics Following Chronic Drug Exposure -- Histone Acetylation -- Histone Methylation -- DNA Methylation and Other Histone Modifications -- MicroRNAs -- Conclusion -- References -- Chapter 11: Role of Stress-Associated Signaling in Addiction -- Introduction -- Stress and Addiction -- Stress and the Progression and Cycle of Drug Use in Addiction -- Addiction-Related Neurocircuitry -- Chapter Goals -- Overview of Stress Influence on Addiction -- Overview of the Stress Response -- Modes of Stress Regulation of Addiction. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Primary Stress Response Signaling and Circuitry -- Secondary Stress Circuitry -- Neuropeptide Mediators of Stress Responses -- Influence of Stress on Addiction Process -- Initiation/Predisposition -- Early Life -- Prenatal/Perinatal Stress -- Juvenile/Adolescent Stress -- Adulthood -- Acquisition -- Escalation -- Relapse -- Stress-Triggered Relapse -- Stress-Potentiated Relapse -- Withdrawal -- Summary of the Contribution of Stress to Cocaine Addiction -- Stress Signaling Mechanisms in Addiction -- Initiation/Predisposition -- Early Life -- Adulthood -- Acquisition -- Escalation -- Relapse -- Stress-Triggered Relapse -- The Extended Amygdala -- Central Amygdala -- Bed Nucleus of the Stria Terminalis -- The Mesocorticolimbic System -- Ventral Tegmental Area -- Prefrontal Cortex -- Nucleus Accumbens -- NAc-core -- NAc-shell -- Stress-Potentiated Reinstatement -- Drug-Induced Adaptations in Stress-Signaling Mechanisms -- Escalating Use Patterns -- Withdrawal -- Heightened Stressor Reactivity -- Glucocorticoid Regulation -- Mechanistic Contrasts in Stress-Associated Signaling Between Drug Classes -- Consideration of Sex Differences in Stress-Associated Signaling in Addiction -- Treatment Implications -- Summary -- References -- Chapter 12: Negative Reinforcement Mechanisms in Addiction -- Psychopathological Framework -- Stages of the Addiction Cycle -- From Positive to Negative Reinforcement -- Neurobiological Mechanisms of Negative Reinforcement -- Within-System Neuroadaptations -- Between-System Neuroadaptations -- Individual Differences -- Negative Emotional States and the Extended Amygdala -- Pain and the Opioid Spinomesothalamocortical System -- Implications for Personalized Medicine -- Conclusions -- References -- Chapter 13: Circadian Rhythms and Addiction -- Introduction -- The Circadian Timing System. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Hierarchical Organization of the Circadian System. |
| 588 ## - SOURCE OF DESCRIPTION NOTE | |
| Source of description note | Description based on publisher supplied metadata and other sources. |
| 590 ## - LOCAL NOTE (RLIN) | |
| Local note | Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Neuropsychiatry. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drug addiction-Psychological aspects. |
| 655 #4 - INDEX TERM--GENRE/FORM | |
| Genre/form data or focus term | Electronic books. |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Print version: |
| Main entry heading | Torregrossa, Mary |
| Title | Neural Mechanisms of Addiction |
| Place, publisher, and date of publication | San Diego : Elsevier Science & Technology,c2018 |
| International Standard Book Number | 9780128122020 |
| 797 2# - LOCAL ADDED ENTRY--CORPORATE NAME (RLIN) | |
| Corporate name or jurisdiction name as entry element | ProQuest (Firm) |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://ebookcentral.proquest.com/lib/orpp/detail.action?docID=5501834">https://ebookcentral.proquest.com/lib/orpp/detail.action?docID=5501834</a> |
| Public note | Click to View |
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